Navigation Links
Psoriasis is associated with impaired HDL function, Penn study finds
Date:11/16/2011

Orlando - Collaborative research from Perelman School of Medicine at the University of Pennsylvania has shown that psoriasis patients have an increased risk of heart attack, stroke and cardiovascular death, especially if the psoriasis is moderate to severe. Now, Penn researchers have discovered the potential underlying mechanism by which the inflammatory skin disease impacts cardiovascular health. In two new studies presented at the 2011 American Heart Association Scientific Sessions, Penn researchers show that the systemic inflammatory impact of psoriasis may alter both the makeup of cholesterol particles and numbers, as well as impair the function of high density lipoprotein (HDL), the "good" cholesterol.

"Anecdotally, many researchers have observed that HDL levels may be lower in states of inflammation, such as rheumatoid arthritis, psoriasis and even obesity," said lead study author Nehal Mehta, MD, MSCE, director of Inflammatory Risk in Preventive Cardiology at Penn. "However, these new findings suggest that in addition to lower levels, chronic inflammation associated with conditions like psoriasis may change the composition and decrease the function of HDL as well."

In the current studies, researchers enrolled 78 patients with psoriasis and 84 control subjects. In the first study, the authors measured fasting lipid levels and examined the number and size of cholesterol particles using nuclear magnetic resonance (NMR) spectroscopy. This analysis revealed that patients with psoriasis had a higher number of smaller LDL particles, or "bad" cholesterol, which was independent of traditional risk factors and obesity. "It was striking that the NMR profiles from patients with psoriasis resembled those seen in patients with diabetes, and that these patients with psoriasis had otherwise normal traditional lipid panels" Dr. Mehta added.

In the second study, the researchers measured HDL efflux, which is the ability of a patient's HDL t
'/>"/>

Contact: Jessica Mikulski
jessica.mikulski@uphs.upenn.edu
215-796-4829
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Experimental Psoriasis Drug Bests Older Treatment
2. 1 in 4 With Psoriasis May Have Undiagnosed Arthritis
3. Kids With Psoriasis Get Inconsistent Care
4. Injectable Psoriasis Drugs May Not Hike Heart Risks: Study
5. Scientists Close in on Origins of Psoriasis, Eczema
6. Some Drugs for Rheumatoid Arthritis, Psoriasis May Cut Diabetes Risk
7. Multitasking meds: Scientists discover how drug for leukemia, psoriasis, may tackle vascular disease
8. Study Sees Link Between Psoriasis, Obesity in Kids
9. Psoriasis, High Blood Pressure May Be Linked
10. Extremely obese children have higher prevalence of psoriasis, higher heart disease risk
11. Severe psoriasis linked to major adverse cardiovascular events
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... California (PRWEB) January 22, 2015 The City of ... at 10 a.m., to commemorate the 42nd anniversary of the Supreme ... States. , “It’s been 42 years since the Roe vs. Wade ... is still as present as ever,” said City of West Hollywood ...
(Date:1/22/2015)... is a seasoned and trusted leader who consistently delivers trendy ... have it lead the wedding dress industry into the future. ... for the global market. , “The CEO of VogueQueen is ... on continuing the goal of operational excellence and giving back ...
(Date:1/22/2015)... 23, 2015 AngelWeddingDress, the premier women’s ... maternity wedding dresses. View website of AngelWeddingDress.com ... for maternity wedding dresses online for a bridal party. ... high quality for them. Its maternity wedding dresses are ...
(Date:1/22/2015)... New York (PRWEB) January 22, 2015 ... after Fresenius Medical Care recalled its GranuFlo and NaturaLyte ... multidistrict litigation underway in U.S. District Court, District of ... dated January 20th, the Court has remanded a case ...
(Date:1/22/2015)... January 22, 2015 Joan Lunden, award-winning ... speaker at the upcoming 32nd Annual Miami Breast ... Physicians’ Education Resource®, LLC (PER®) , shares that “a ... gone undetected if she had not followed up her ...
Breaking Medicine News(10 mins):Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... Scientific Pioneers Invest in Evolving Field of Protein ... Millennium,Pharmaceuticals, Inc. (Nasdaq: MLNM ) and Harvard ... innovative collaboration,agreement to pursue a research program in ... field of cancer biology. Under the terms of ...
... throughout Minnesota, MINNEAPOLIS, Jan. 31 A ... 76 percent of Minnesotans support the,statewide smoke-free law, ... provides evidence of strong support among all leading,demographics, ... gender. The survey was conducted by Minneapolis research,firm ...
... - New Information Strengthens Community,s Demand to Save St. ... ... Sutter Health told the San,Francisco Chronicle in a January 27 article the ... St. Luke,s,Hospital, the South of Market facility they are trying to close:, ...
... The Company,s first acne product enters the ... Jan. 30 Skinvisible, Inc. (OTC,Bulletin Board: ... company focused on formulating and enhancing patented,dermatology ... announced it has signed an exclusive licensing ...
... Survey of User Satisfaction puts IDC on top ... /PRNewswire-FirstCall/ - IDC (Imaging Dynamics,Company, Ltd.) (TSX: IDL), ... today announced that for the third consecutive,quarter it ... digital,detector radiography systems among 11 vendors in the ...
... N.Y., Jan. 30 Moog Inc. (NYSE:,MOG.A and MOG.B) ... John,Scannell, CFO, will present at the 29th Annual Cowen ... 2008 at 11:10 a.m. EST., Listeners can access ... . Please allow 15 minutes prior,to the call to ...
Cached Medicine News:Health News:Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology 2Health News:Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology 3Health News:Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology 4Health News:Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology 5Health News:Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology 6Health News:New Survey Finds 76 Percent of Minnesotans Support Smoke-Free Law 2Health News:Skinvisible Announces Licensing Agreement for Adapalene 2Health News:Skinvisible Announces Licensing Agreement for Adapalene 3Health News:IDC Digital radiography systems Ranked #1 for third consecutive quarter 2
(Date:1/23/2015)... , January 23, 2015 Heptares Therapeutics, the ... to announce that the Malcolm Campbell Memorial Prize ... (Vice President of Chemistry), Fiona Marshall (Chief Scientific ... Officer and co-founder) for the seminal contributions to GPCR drug ...
(Date:1/22/2015)... DIEGO, Jan. 22, 2015  ResMed Inc. (NYSE: RMD ... 2014. Revenue for the quarter was $423.0 million, a 10 ... (a 14 percent increase on a constant currency basis). Net ... to the quarter ended December 31, 2013. Diluted earnings per ...
(Date:1/22/2015)... Calif. , Jan. 22, 2015 Increasing sophistication ... continued consolidation of localization purchasing in 2015, says ... According to a recent study by market research firm ... a single-source solution for their translation and localization needs. ...
Breaking Medicine Technology:Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 11Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2
... NEW YORK, Nov. 3, 2011 Intellect Neurosciences, ... the discovery and development of disease-modifying therapeutic agents ... diseases announced today that it has filed a ... its antibody methods application Serial  No. 10/084,380, one ...
... 2011 Savient Pharmaceuticals, Inc. (NASDAQ: SVNT ) ... ended September 30, 2011, which reflect the Company,s continuing investment ... quarter with $202.7 million in cash and short-term investments, a ... quarter of 2011, the Company had a net loss of ...
Cached Medicine Technology:Intellect Neurosciences Responds to Official Action by United States Patent and Trademark Office in Relation to its ANTISENILIN® Alzheimer's Patent Application 2Intellect Neurosciences Responds to Official Action by United States Patent and Trademark Office in Relation to its ANTISENILIN® Alzheimer's Patent Application 3Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 2Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 3Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 4Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 5Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 6Savient Pharmaceuticals Reports Third Quarter 2011 Financial Results 7
... offer a wide range of storage capacities. ... storage platform to agitate smoothly, eliminating the ... and squeak. Sturdy, one-piece perforated drawers with ... for your platelets., ,i.Series platelet agitators feature ...
Platelet agitator....
Reciprocating shaker specifically for platelet bags....
... the quantitative determination of ... serum. Progesterone EIA ... principle of competitive binding ... test specimen and progesterone-HRP ...
Medicine Products: