Navigation Links
Psoriasis Raises Risk of Heart Attack, Stroke, Death

Inflammation looks like common thread, researcher says

MONDAY, June 15 (HealthDay News) -- People with psoriasis face an increased risk of major cardiovascular disease and death, a new study finds.

The research, which included data from a Veterans Administration medical facility study to compare 3,236 people suffering from the skin disease to 2,500 psoriasis-free individuals, found a 78 percent higher incidence of heart disease, a 70 percent higher incidence of stroke and a 98 percent higher incidence of peripheral arterial disease (blockage of arteries in the legs) in the psoriasis group.

The overall death rate for those with psoriasis was 86 percent higher than for those without the disease. In the 20 years covered by the study, 19.6 percent of those with psoriasis died, compared to 9.9 percent of those without the disease.

The cardiovascular disease calculations included effects of known risk factors such as obesity, smoking, diabetes and high blood cholesterol, said study co-author Dr. Robert S. Kirsner, vice chairman of dermatology at the University of Miami Miller School of Medicine. The team reports the finding in the June issue of the Archives of Dermatology.

"In and of itself, psoriasis imparts a risk of cardiac disease, stroke and peripheral arterial disease," Kirsner said. "Psoriasis imposes the same level of risk as high blood lipids and smoking."

The risk appears to stem from the chronic inflammation associated with psoriasis, he explained. "This systemic inflammation causes damage to blood vessels, leading to increased risk," he said.

The medical lesson of the study is that "it is critical for people who have psoriasis to understand their increased risk and have their other risk factors addressed," he said.

Cardiovascular risk is linked to the severity of the skin disease, Kirsner said, and "there are some data suggesting that treating psoriasis can lower the risk."

However, the data are only suggestive, noted Dr. Joel M. Gelfand, medical director of the University of Pennsylvania's department of dermatology clinical studies unit, which has published several reports showing the same association.

One of his group's studies, using British data, found a 55 percent increased cardiovascular risk and a 78 percent higher death rate in persons with psoriasis, Gelfand said. "But we don't have enough data to know if controlling psoriasis would also control those risks," he said. "This is a key public health question best answered in a randomized, controlled trial."

Like Kirsner, Gelfand stressed the need to address traditional cardiovascular risk factors in people with psoriasis. "Patients who have psoriasis, especially severe cases, should be screened for modifiable risk factors," Gelfand said. "We have a plan in place for our patients to achieve a healthy lifestyle, a plan that includes weight control and exercise."

Psoriasis affects 2 percent to 3 percent of the world's population, including 7 million Americans, the new report estimated.

More information

Details on psoriasis can be found at the U.S. National Library of Medicine.

SOURCES: Robert S. Kirsner, M.D., Ph.D., professor and vice chairman, dermatology, University of Miami Miller School of Medicine; Joel M. Gelfand, M.D., medical director, University of Pennsylvania department of dermatology clinical studies unit, Philadelphia; June 2009 Archives of Dermatology

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
2. Americas Next Top Model Steps up for Psoriasis Awareness
3. Chicagoland Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
4. Psoriasis Cure Now Rolls Out First National Short Sleeve Day Saturday
5. DC Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
6. Salt Lake City Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
7. San Francisco Psoriasis Event Tonight Will Celebrate First National Short Sleeve Day
8. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
9. National Psoriasis Foundation Marks World Psoriasis Day With Call to Support Psoriasis Legislation
10. New study shows smoking increases risk of psoriasis
11. $6.37 million from National Institutes of Health to find new ways to treat psoriasis
Post Your Comments:
Related Image:
Psoriasis Raises Risk of Heart Attack, Stroke, Death
(Date:11/27/2015)... ... November 27, 2015 , ... A simply groundbreaking television series, "Voices ... show that delves into an array of issues that are presently affecting Americans. Dedicated ... open dialogue, this show is changing the subjects consumers focus on, one episode at ...
(Date:11/27/2015)... ... 2015 , ... Dr. Thomas Dunlap and Dr. Patrick Coleman ... with Emergency Medicine at St., Joseph Health System’s Santa Rosa Memorial Hospital , ... in similar ways and require time-critical intervention to avoid large area heart damage and ...
(Date:11/26/2015)... ... November 26, 2015 , ... CognisantMD ... for diagnostic imaging in the Waterloo region. Using the Ocean Platform, family physicians ... directly from their electronic medical record (EMR) without the need for redundant patient ...
(Date:11/26/2015)... ... November 26, 2015 , ... WorldCare International, Inc., ... the 61st annual Employee Benefits Conference. The Employee Benefits Conference was hosted by ... through Wednesday, November 11th, 2015. The conference was held at the Hawaii Convention ...
(Date:11/25/2015)... IN (PRWEB) , ... November 25, 2015 , ... ... water accessible for all, Water For Empowerment ™ attracts volunteers together who ... clean water by empowering women as key stakeholders in the process. The non-profit ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)...  Linden Care, LLC, a retail specialty pharmacy focused ... suffering from chronic pain, said today that it is ... (TRO) enjoining Express Scripts from unilaterally terminating the Pharmacy ... --> --> The company said that ... --> --> In ...
(Date:11/25/2015)... USA , Inc., a leader in ... accuracy of its blood glucose meter systems. Last week ... Cardiovascular Disease in Los Angeles , ... 01 meter and the Assure ® Prism multi-user ... measure glucose levels in blood is essential for people ...
(Date:11/25/2015)... DUBLIN , Nov. 25, 2015 Allergan plc ... an agreement with the New York State ... 2 of the Sherman Act, and other statutes with the ... in February 2014, to cease marketing and selling the now ... of settlement, Allergan admits no liability, has released its counterclaims ...
Breaking Medicine Technology: