Navigation Links
Psoriasis Raises Risk of Heart Attack, Stroke, Death
Date:6/15/2009

Inflammation looks like common thread, researcher says

MONDAY, June 15 (HealthDay News) -- People with psoriasis face an increased risk of major cardiovascular disease and death, a new study finds.

The research, which included data from a Veterans Administration medical facility study to compare 3,236 people suffering from the skin disease to 2,500 psoriasis-free individuals, found a 78 percent higher incidence of heart disease, a 70 percent higher incidence of stroke and a 98 percent higher incidence of peripheral arterial disease (blockage of arteries in the legs) in the psoriasis group.

The overall death rate for those with psoriasis was 86 percent higher than for those without the disease. In the 20 years covered by the study, 19.6 percent of those with psoriasis died, compared to 9.9 percent of those without the disease.

The cardiovascular disease calculations included effects of known risk factors such as obesity, smoking, diabetes and high blood cholesterol, said study co-author Dr. Robert S. Kirsner, vice chairman of dermatology at the University of Miami Miller School of Medicine. The team reports the finding in the June issue of the Archives of Dermatology.

"In and of itself, psoriasis imparts a risk of cardiac disease, stroke and peripheral arterial disease," Kirsner said. "Psoriasis imposes the same level of risk as high blood lipids and smoking."

The risk appears to stem from the chronic inflammation associated with psoriasis, he explained. "This systemic inflammation causes damage to blood vessels, leading to increased risk," he said.

The medical lesson of the study is that "it is critical for people who have psoriasis to understand their increased risk and have their other risk factors addressed," he said.

Cardiovascular risk is linked to the severity of the skin disease, Kirsner said, and "there are some data suggesting that treating psoriasis can lower the risk."

However, the data are only suggestive, noted Dr. Joel M. Gelfand, medical director of the University of Pennsylvania's department of dermatology clinical studies unit, which has published several reports showing the same association.

One of his group's studies, using British data, found a 55 percent increased cardiovascular risk and a 78 percent higher death rate in persons with psoriasis, Gelfand said. "But we don't have enough data to know if controlling psoriasis would also control those risks," he said. "This is a key public health question best answered in a randomized, controlled trial."

Like Kirsner, Gelfand stressed the need to address traditional cardiovascular risk factors in people with psoriasis. "Patients who have psoriasis, especially severe cases, should be screened for modifiable risk factors," Gelfand said. "We have a plan in place for our patients to achieve a healthy lifestyle, a plan that includes weight control and exercise."

Psoriasis affects 2 percent to 3 percent of the world's population, including 7 million Americans, the new report estimated.

More information

Details on psoriasis can be found at the U.S. National Library of Medicine.



SOURCES: Robert S. Kirsner, M.D., Ph.D., professor and vice chairman, dermatology, University of Miami Miller School of Medicine; Joel M. Gelfand, M.D., medical director, University of Pennsylvania department of dermatology clinical studies unit, Philadelphia; June 2009 Archives of Dermatology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
2. Americas Next Top Model Steps up for Psoriasis Awareness
3. Chicagoland Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
4. Psoriasis Cure Now Rolls Out First National Short Sleeve Day Saturday
5. DC Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
6. Salt Lake City Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day
7. San Francisco Psoriasis Event Tonight Will Celebrate First National Short Sleeve Day
8. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
9. National Psoriasis Foundation Marks World Psoriasis Day With Call to Support Psoriasis Legislation
10. New study shows smoking increases risk of psoriasis
11. $6.37 million from National Institutes of Health to find new ways to treat psoriasis
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Psoriasis Raises Risk of Heart Attack, Stroke, Death
(Date:6/26/2016)... ... 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop ... The fitness app plans to fix the two major problems leading the fitness industry today:, ... all type program , They don’t eliminate all the reasons people quit their ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
(Date:6/23/2016)... a startling report released today, National Safety Council research ... proven plan to eliminate prescription opioid overdoses. Prescription Nation ... tackling the worst drug crisis in recorded U.S. history, assigned a ... , New Mexico , Tennessee ... failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
Breaking Medicine Technology: