Navigation Links
Psoriasis, High Blood Pressure May Be Linked
Date:5/20/2011

FRIDAY, May 20 (HealthDay News) -- People who have psoriasis and hypertension are more likely to have more severe high blood pressure, requiring more medications to control it, a new study suggests.

About 4 percent of the U.S. population has psoriasis, which causes itchy, thickened, dry, red patches on the skin.

Researchers from the University of California, Davis Health System examined 835 patients who had psoriasis and hypertension. Their cases were compared with more than 2,400 people who had hypertension but not psoriasis.

The patients with psoriasis were more likely to need the highest level of blood pressure treatment, which relies on a central-acting agent (also known as adrenergic inhibitors) that's used in people whose high blood pressure can't be controlled with conventional medications.

Hypertensive patients with psoriasis were also nearly 20 times more likely to be on four drugs or on a central-acting agent than hypertensive patients without psoriasis.

The study is published online in PLoS One.

The study's authors noted the findings were significant even after other risk factors associated with hypertension, including diabetes, smoking and high cholesterol, were taken into account. The researchers also pointed out it is unlikely that drugs used to treat psoriasis are responsible for the increased severity of hypertension.

"Our study makes a strong case that psoriasis is not just a skin-deep disease," said lead study author Dr. April W. Armstrong, UC Davis assistant clinical professor of dermatology, in a university news release. "We are beginning to find that psoriasis may represent a window into detecting cardiovascular conditions, including hypertension."

Armstrong added that the findings may alert physicians who treat hypertension, a risk factor for heart disease and stroke. "Hypertensive patients who also have psoriasis are likely to need closer monitoring and a more aggressive drug regimen to achieve adequate blood-pressure control," she said.

Over the past four decades, researchers have developed several theories to explain the link between psoriasis and hypertension, including:

  • People with psoriasis may be more likely to develop constricted blood vessels, which increases blood pressure.
  • Patients with psoriasis have elevated levels of a protein produced by skin cells (endothelin I), which constricts blood vessels and increases blood pressure.
  • As an inflammatory disease, psoriasis can result in damage to blood vessels and the heart.

"Our understanding of psoriasis as a systemic disease is rapidly evolving," concluded Armstrong. "A better appreciation of the other conditions that tend to accompany psoriasis could potentially drive our therapy of the disease in the future."

While the new study found an association between psoriasis and high blood pressure, it did not demonstrate a cause-and-effect.

More information

The U.S. National Institutes of Health offers more detailed information on psoriasis.

-- Mary Elizabeth Dallas

SOURCE: UC Davis Health System, news release, May 12, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Extremely obese children have higher prevalence of psoriasis, higher heart disease risk
2. Research provides insight into quality of stored blood used for transfusions
3. Unnecessary Blood Tests Plunge After Cost Reminders: Study
4. Findings could lead to a blood test for lung cancer
5. Study reveals origins of a cancer affecting the blood and bone marrow
6. Chronic Tylenol Use May Be Linked to Blood Cancer, Study Suggests
7. Blood test for colon cancer screening beneficial for some seniors, but not for many others
8. Adalimumab levels detected in cord blood and infants exposed in utero
9. Blood Pressure May Hint at Kidney Cancer Outcome
10. Structured Exercise Programs Help Lower Blood Sugar, Study Finds
11. Religion Doesnt Help Lower Blood Pressure, Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/26/2017)... ... July 26, 2017 , ... ... Solutions as part of their continued efforts to provide innovative offerings to their ... best IT resources and build dynamic, high-performing teams to address healthcare IT’s biggest ...
(Date:7/26/2017)... ... July 26, 2017 , ... The ... Process Validation and Process Validation Statistics Conferences in Bethesda, Maryland, 12 – ... challenges faced by process validation professionals and statisticians today. , “These conferences ...
(Date:7/26/2017)... (PRWEB) , ... July 26, 2017 , ... “We are ... offer the ability for patients to schedule an appointment online in real time,” said ... the Six Month Smiles provider directory will bring more Six Month Smiles patients to ...
(Date:7/26/2017)... ... , ... The Amnesty Rally 2017 will be held on Saturday, July 29 ... Drive in Monroe (adjacent to the Louisiana Purchase Gardens & Zoo). , The ... Monroe. Citizens can turn in unregistered, illegally-held and imitation guns to law enforcement officers ...
(Date:7/25/2017)... St. Louis, MO (PRWEB) , ... July 25, 2017 , ... ... (HDIS) in St. Louis, Missouri. The company has achieved record-breaking sales for ... multiple departments over the next 12 months. , The upcoming year offers excitement and ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... know that PhRMA member companies invested $65.5 billion in research and ... generics and the supply chain account for 14 percent of total ... (7 percent)? Or that the United States ... high-growth biopharmaceutical startups? ... The biopharmaceutical industry accounts for 1 ...
(Date:7/17/2017)... , July 17, 2017  MedX Holdings, Inc., ... medical testing, strengthening and rehabilitation equipment, today announced the ... Program. MedX is considered the gold standard for the ... in specialized medical strengthening equipment. ... lease with the physician or practice who prescribe the ...
(Date:7/14/2017)... It should come as no surprise to anyone that ... of a crippling opioid epidemic. According to the Center ... deaths from opiate-based medications has quadrupled, Says, Dr. David ... 2001 to 2015". During this time, the prescription rate for ... a compelling link between prescription and eventual addiction. The problem ...
Breaking Medicine Technology: