Navigation Links
Psoriasis, High Blood Pressure May Be Linked
Date:5/20/2011

FRIDAY, May 20 (HealthDay News) -- People who have psoriasis and hypertension are more likely to have more severe high blood pressure, requiring more medications to control it, a new study suggests.

About 4 percent of the U.S. population has psoriasis, which causes itchy, thickened, dry, red patches on the skin.

Researchers from the University of California, Davis Health System examined 835 patients who had psoriasis and hypertension. Their cases were compared with more than 2,400 people who had hypertension but not psoriasis.

The patients with psoriasis were more likely to need the highest level of blood pressure treatment, which relies on a central-acting agent (also known as adrenergic inhibitors) that's used in people whose high blood pressure can't be controlled with conventional medications.

Hypertensive patients with psoriasis were also nearly 20 times more likely to be on four drugs or on a central-acting agent than hypertensive patients without psoriasis.

The study is published online in PLoS One.

The study's authors noted the findings were significant even after other risk factors associated with hypertension, including diabetes, smoking and high cholesterol, were taken into account. The researchers also pointed out it is unlikely that drugs used to treat psoriasis are responsible for the increased severity of hypertension.

"Our study makes a strong case that psoriasis is not just a skin-deep disease," said lead study author Dr. April W. Armstrong, UC Davis assistant clinical professor of dermatology, in a university news release. "We are beginning to find that psoriasis may represent a window into detecting cardiovascular conditions, including hypertension."

Armstrong added that the findings may alert physicians who treat hypertension, a risk factor for heart disease and stroke. "Hypertensive patients who also have psoriasis are likely to need closer monitoring and a more aggressive drug regimen to achieve adequate blood-pressure control," she said.

Over the past four decades, researchers have developed several theories to explain the link between psoriasis and hypertension, including:

  • People with psoriasis may be more likely to develop constricted blood vessels, which increases blood pressure.
  • Patients with psoriasis have elevated levels of a protein produced by skin cells (endothelin I), which constricts blood vessels and increases blood pressure.
  • As an inflammatory disease, psoriasis can result in damage to blood vessels and the heart.

"Our understanding of psoriasis as a systemic disease is rapidly evolving," concluded Armstrong. "A better appreciation of the other conditions that tend to accompany psoriasis could potentially drive our therapy of the disease in the future."

While the new study found an association between psoriasis and high blood pressure, it did not demonstrate a cause-and-effect.

More information

The U.S. National Institutes of Health offers more detailed information on psoriasis.

-- Mary Elizabeth Dallas

SOURCE: UC Davis Health System, news release, May 12, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Extremely obese children have higher prevalence of psoriasis, higher heart disease risk
2. Research provides insight into quality of stored blood used for transfusions
3. Unnecessary Blood Tests Plunge After Cost Reminders: Study
4. Findings could lead to a blood test for lung cancer
5. Study reveals origins of a cancer affecting the blood and bone marrow
6. Chronic Tylenol Use May Be Linked to Blood Cancer, Study Suggests
7. Blood test for colon cancer screening beneficial for some seniors, but not for many others
8. Adalimumab levels detected in cord blood and infants exposed in utero
9. Blood Pressure May Hint at Kidney Cancer Outcome
10. Structured Exercise Programs Help Lower Blood Sugar, Study Finds
11. Religion Doesnt Help Lower Blood Pressure, Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... , ... January 20, 2017 , ... “The Angel”: ... Lord has set out for each of his children. “The Angel” is the creation ... of Music in New York City, and impassioned writer. , When asked of her ...
(Date:1/20/2017)... ... ... beautiful and enchanting tale that teaches children the true meaning of Christmas. “Journey to Christmas” ... and a devoted woman of faith. , “Becoming a parent changes you. In my ... mind for years, but actually doing it might have been a while in coming if ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... On-demand E-learning system for Clinical and Regulatory education for Physicians, Physician Advisors, ... Aerolib`s successful education methodology of Disease Specific Documentation Improvement. , The Aerolib ...
(Date:1/19/2017)... (PRWEB) , ... January 19, 2017 , ... ... for tech innovators, engineers, and scientists from around the world, announces the launch ... users a quick and easy portal to research breakthroughs and trending news, vital ...
(Date:1/19/2017)... ... January 19, 2017 , ... Catalent Pharma Solutions, the ... and consumer health products, today announced that it will be co-hosting a workshop ... excipients and drug delivery solutions to health industries worldwide. The one day event ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... 19, 2017 Pfizer joins ... Milner Therapeutics Consortium   Major research ... Cambridge   The Milner Therapeutics ... ) as a partner to the Milner Therapeutics Consortium. ... the efficient transfer of materials between industry and academia ...
(Date:1/19/2017)... The global  pacemaker market  is expected to reach USD 12.3 billion by ... prevalence of cardiac conditions coupled with the availability of medical coverage is a ... in these devices are supporting the expansion of this vertical. ... ... View Research Logo ...
(Date:1/19/2017)... 18, 2017 The Global Therapy Partnering Terms ... to partnering deals and agreements entered into by the ... deals - Top deals by value - Deals listed ... type The report provides understanding and access to ... world,s leading healthcare companies. The report provides an ...
Breaking Medicine Technology: