Navigation Links
Prune juice not necessary: New research should make bowel movements easier
Date:4/8/2009

If you hate prune juice and chalky fiber supplements, just sit down and relax. Help is on the way. In a research report published online in The FASEB Journal (http://www.fasebj.org), a team of researchers has discovered a new way to make it a lot easier to go to the bathroom, especially when all other methods fail. Specifically, they have found a group of nerve ending receptors which, when stimulated, causes the bowels to pass waste, and the specific receptor needed to activate bowel clearance. Furthermore, they tested chemicals that work with those receptors, providing a blueprint for the development of new laxatives.

"We hope that the receptor identified by our study would be exploited more in the design of drugs to treat constipation," said Bindu Chandrasekharan, a researcher from Emory University who was involved in the study.

The research involved two groups of mice, focusing on a type of receptor also present on human nerves in the gut (a type of adenosine receptor). The first group of mice had normal adenosine receptors on these nerves and normal bowel movements. The second group of mice completely lacked these adenosine receptors and showed familiar signs of constipation. The researchers started with simple experiments such as comparing the wet weight, dry weight, and water content in the stools of both groups. The mice were also made to drink a dye not absorbed by the body to see how it passed or did not pass. In addition, the researchers used microscopic lasers to separate the nerve cells from the bowel to determine exactly where the receptors are located. Then they tested various chemicals that can activate or inhibit the nerve receptors.

"I actually like prune juice, but I find the study to be very compelling," said Gerald Weissmann, M.D, Editor-in-Chief of The FASEB Journal. "Here's why: First, we can look forward to a solution to what is sometimes a serious problem, especially infants and the elderly. Second, it's the first definitive proof that these receptors, the adenosine receptors, control bowel function. This discovery promises to yield agents that will permit us to sit down and ease up in the middle of a busy day."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related medicine news :

1. From Early Brain Development to Digestive Health, New Juicy Juice Beverages Aid Children Through Different Stages of Growth and Development
2. Diabetics May Soon Have Low-Sugar Vegetable Juice
3. CEO of iZO Cleanze Completes Day 50 of 100-Day Juice Cleanse
4. Precautionary Allergy Alert on Undeclared Milk Protein in Expired Codes of Broughton Foods Pints of Orange Juice, Citrus Punch, Fruit Punch and Iced Tea Products
5. ABC Releases Monograph on Scientific Research of POM Wonderful(R) Pomegranate Juice
6. Cranberry juice creates energy barrier that keeps bacteria away from cells, study shows
7. Nestle Juicy Juice Kicks Off Summer Promoting Nutritious, Active Lifestyle Choices Among Latino Children, Families
8. AVP Crocs Tour Announces Season-Long Contract With Naked Juice
9. Kagomes Yellow Mango Orchard Blended Juice Named One of Americas Healthiest Buys
10. Reported Health Benefits of Tart Cherry Boosts Juice Distribution in Southern U.S.
11. Fruit Juice May Be Healthy for Kids: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Abilene, Texas (PRWEB) , ... October 13, 2017 , ... ... publication this week that explains one of the most popular and least understood books ... seems like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
(Date:10/12/2017)... ... , ... The American College of Medical Informatics (ACMI) will present the 2017 ... Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is ... pioneer in the field of medical informatics, this prestigious award is presented to an ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at ... for the 49th Congress of the International Society of Paediatric Oncology (SIOP) ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. ...
(Date:10/12/2017)... ... 2017 , ... Vohra Chief Medical Officer Dr. Shark Bird, ... nursing facility medical directors and other clinicians at various events in October. His ... many of these conferences we get to educate other physicians, facility nurses, corporate ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 ... mobile health and big data solutions, today announced that its MyDario product ... check your local TV listings for when The Dr. Oz Show airs ... The ... this month. ...
(Date:9/22/2017)... -- As the latest Obamacare repeal effort moves is debated, ... and Lindsey Graham (R-SC) medical device market ... is in an odd place.  The industry wants repeal ... on medical device sales passed along with the Affordable ... visits and hospital customers with the funding to invest ...
(Date:9/18/2017)... ALLENTOWN , Pa. and KALAMAZOO, Mich. ... Allentown, Penn. , and OptiMed Specialty Pharmacy ... a business partnership to offer a strategic hub service ... PMD Healthcare,s highly sought-after personal spirometer, Spiro PD 2.0, ... A spirometer is a medical device used ...
Breaking Medicine Technology: