Navigation Links
Prozac Reduces Disease Activity in MS Patients

Small study finds antidepressant cut inflammation in relapsing remitting illness

WEDNESDAY, April 30 (HealthDay News) -- Prozac may help reduce disease activity in people with the relapsing remitting form of multiple sclerosis (MS), a new study suggests.

Forty patients with the disease were randomly selected to receive either 20 milligrams a day of fluoxetine (Prozac) or a placebo for 24 weeks. MRI brain scans were conducted every four weeks to monitor the patients for new areas of neurological inflammation, a hallmark of disease activity.

Of the 38 patients (19 in each group) who completed the study, those who took the placebo had more new areas of inflammation (average of more than five areas) than those who took the drug (average of just under two).

One in four scans from patients treated with fluoxetine showed new areas of inflammation, compared with four out of 10 scans from patients taking the placebo. During the last 16 weeks of treatment, 63 percent of patients in the fluoxetine group had no new areas of inflammation, compared with 26 percent of those in the placebo group.

The findings were published online in the Journal of Neurology Neurosurgery and Psychiatry.

This was a small study, and larger studies are needed before any firm conclusions about the use of fluoxetine in patients with relapsing remitting MS can be made, the study authors noted.

However, the findings are "sufficiently encouraging to justify further studies with fluoxetine in patients with MS," they said, and added that higher doses and treatment combinations with other drugs that alter the immune response should be considered in future studies.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about multiple sclerosis.

-- Robert Preidt

SOURCE: BMJ Specialist Journals, news release, May 1, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Prozac Makes Old Brain Cells Young
2. Staff Training Reduces Postpartum Bleeding, Episiotomies
3. Gene Therapy in Rats Reduces Cocaine Use
4. Study shows pine bark naturally reduces osteoarthritis
5. Study Shows Pine Bark Naturally Reduces Osteoarthritis
6. Gene therapy reduces cocaine use in rats
7. Pill Reduces Relapses in MS Patients
8. Essential Nutrient Found in Eggs Reduces Risk of Breast Cancer by 24 Percent
9. Essential nutrient found in eggs reduces risk of breast cancer by 24 percent
10. Psychological intervention reduces postembolization pain
11. Aspirin Reduces Asthma Risk Among Older Women
Post Your Comments:
(Date:11/28/2015)... ... November 28, 2015 , ... StatRad , ... added Chris Hafey and Claude Hooton to its board of directors. The announcement ... America (RSNA) 2015 Annual Meeting and continues to strategically transform its focus from ...
(Date:11/28/2015)... ... November 28, 2015 , ... Beginning November 30th at 6:00 a.m. EST until 11:59 p.m. EST, ... With possible savings of up to 20% off orders $80 or more to free gifts ... every few hours. , As a competitive e-commerce website for skin care and cosmetic needs, ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published November ... meeting in Washington D.C. revolved around the fact that proper dental care, both at-home ... stressed the link between periodontal disease (more commonly referred to as gum disease) and ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... affecting the health care in America. As people age, more care is needed, ... costs are rising, and medical professionals are being overworked. The forgotten part of ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When ... said an inventor from Hillside, N.J. "Many people catch diseases simply from sitting ... individuals will always be protected from germs." , He developed the patent-pending QUDRATECS ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ... which demands kidney transplantation is expected to boost the market ... for organ transplantation. --> 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ...
(Date:11/26/2015)... November 26, 2015 ... universitetssjukhus ser potential att använda SyMRI för ... för patienter med multipel skleros (MS) ... med SyntheticMR AB för att kunna använda ... sjukhuset. Med SyMRI kan man generera flera ...
(Date:11/26/2015)... Research and Markets ( ) ... Future Horizons and Growth Strategies in the Italian ... Segment Forecasts, Competitive Intelligence, Emerging Opportunities" report ... --> This new 247-page report ... drug monitoring market, including emerging tests, technologies, instrumentation, ...
Breaking Medicine Technology: