Navigation Links
Protocol for a clinical study on reduced toxicant prototype cigarettes published
Date:7/28/2013

British American Tobacco has published the protocol for a clinical study designed to determine whether using reduced-toxicant prototype cigarettes that reduce smokers' exposure to smoke toxicants impacts biological effect (ISRCTN81286286).

The study protocol refers to the 'recipe' used to conduct a study, describes what will be done during the study, how this will be done and why it is being done.

This study follows a previous study by researchers at British American Tobacco that showed that it is possible to reduce smokers' exposure to certain smoke toxicants by switching them to novel prototype cigarettes with lower amounts of some toxicants in the smoke (doi:10.1016/j.yrtph.2013.02.007). This was a short-term study, lasting six weeks. Now a second clinical study will assess whether this reduced exposure is maintained over the longer term, and also whether longer term exposure reduction results in detectable changes in biological effect.

The prototype cigarettes used in both studies contained technologies designed to reduce key toxicants in smoke. A resin that removes aldehydes and a nano-porous carbon that traps volatile smoke compounds were added to the filter. An enzyme-treatment was used on the tobacco to remove proteins and polyphenols that become toxicants when burned, and inert calcium carbonate and glycerol were added to dilute the smoke.

BAT combined these technologies into three different prototype cigarettes and showed in a clinical study that there was a reduction in exposure to certain toxicants in smokers who switched to the prototype cigarettes for six weeks.

However, that study was not long enough to explore the potential for a reduction in risk of smoking-related diseases or adverse biological effects. Now a longer-term (six months) study will determine whether use of prototype cigarettes leads to both continued reductions in exposure to toxicants and beneficial changes in the body, as shown by assessment of
'/>"/>

Contact: Dr. Marina Murphy
marina_murphy@bat.com
44-077-111-50135
R&D at British American Tobacco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New treatment protocol extends survival in some cases of once inoperable pancreatic cancer
2. Researchers develop secure protocol for linking data registries for HPV surveillance
3. ASTRO: Deviating from radiation protocols increases risk of treatment failure and death
4. Dr. Robbins Updates HCG EZ Drops Diet Protocols
5. Comprehensive maternal hemorrhage protocols improve patient safety
6. Delgado Protocol Announces Adrenal DMG, An Amazing New Supplement Designed to Support the Immune, Circulatory and Cardiovascular Systems
7. Standard CT protocol for trauma patients leads to overutilization of imaging
8. Audiology Associates Explains New Hearing Aid Protocol in Honor of Better Hearing and Speech Month
9. Delgado Protocol For Health Introduces Stay Young, A Powerful New Anti-Aging Supplement
10. Keller Family Dental Explains their Infection Control Protocols
11. PilotFish Expand’s Healthcare Integration Capabilities with Support for the New Direct Protocol in Its Latest Product Release
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... (PRWEB) September 30, 2014 For most ... the apple orchard, pumpkin patch or annual festival. For ... fast-spreading viruses – like the respiratory infection Enterovirus D68. ... most children, a small percentage – especially children with ... Increased concern about the Enterovirus is prompting hospitals across ...
(Date:9/30/2014)... Columbus, Ohio (PRWEB) September 30, 2014 ... and new viral strains emerging every day, it’s ... disinfecting system. The EnviroShield system is an ... and allows applications to surface normally missed with ... a spray nozzle that adds an electrostatic negative ...
(Date:9/30/2014)... A group of Americans is headed to ... that, left unchecked, could create a catastrophic, global pandemic. No, ... Africa. John Rogers, the Executive Director the Eugene Bell Foundation ... a disease most think mankind conquered long ago: tuberculosis. , ... is on the comeback in several countries - what’s especially ...
(Date:9/30/2014)... Two revolutionary procedures now being utilized by ... disease a far less painful and far more effective ... ever felt electric shock waves surge through your teeth as ... it’s possible you already know the impact of receding gums,” ... dentist in West Palm Beach, and a Fellow in the ...
(Date:9/30/2014)... TUESDAY, Sept. 30, 2014 (HealthDay News) -- Medicare should ... at high risk for the disease, a coalition of ... The coalition, which includes the Lung Cancer Alliance, the ... the American Cancer Society and the American Society of ... Monday to the U.S. Centers for Medicare & Medicaid ...
Breaking Medicine News(10 mins):Health News:As Hospitals Combat Enterovirus Outbreaks, Patients and Families Turn to “Virtual Visits” with CaringBridge 2Health News:Columbus Janitorial Company Announces New Disinfecting System for your workplace 2Health News:US Delegation Heads to North Korea to Combat Tuberculosis Epidemic 2Health News:Florida Dentist Battles Gum Disease With Latest Techniques 2Health News:Florida Dentist Battles Gum Disease With Latest Techniques 3Health News:Groups Call for Medicare Coverage of Lung Cancer Screening 2
... By Alan Mozes HealthDay Reporter , THURSDAY, March ... a common facet of dating for America,s adolescents, a new ... graders found that more than 37 percent of 11- to ... psychological violence, and almost one in six said they had ...
... (HealthDay News) -- Although eight states boosted their sales taxes ... in the number of such increases by states compared to ... Control and Prevention shows. One thing that smoking prevention ... as cigarette prices go up, the CDC said. ...
... common kidney cancer subtype, face a low risk of tumour ... findings of a multi-centre study of nearly 600 patients published ... . "Because papillary renal cell carcinoma ... the small number of patients enrolled in individual studies makes ...
... , WEDNESDAY, March 28 (HealthDay News) -- Tourists over age 65 ... die from the disease than those ages 18 to 35, a ... from more than 25,000 U.K. patients also found that the malaria ... West Africa. The risk of dying from malaria, an infection ...
... As part of an isolated indigenous group in central ... fishing, and clearing land by hand to grow crops. Their ... day might imply they have higher than average male testosterone ... of Washington have found, however, that the baseline testosterone level ...
... the World Health Organization (WHO) estimates that 20.1 million ... 1 and 2 across 9 world regions in 2005. ... Hepatology , a journal published by Wiley-Blackwell on ... Liver Diseases, there were 3.4 million symptomatic cases, 70,000 ...
Cached Medicine News:Health News:Dating Violence Common by 7th Grade: Survey 2Health News:Dating Violence Common by 7th Grade: Survey 3Health News:States' Efforts to Boost Cigarette Taxes Slows: CDC 2Health News:Kidney cancer subtype study finds low recurrence and cancer death rates 2Health News:Older Travelers at Much Higher Risk of Dying From Malaria 2Health News:Low testosterone level in Amazonian tribe responds to competition 2Health News:Over 20 million individuals infected with hepatitis E in Asia and Africa 2
(Date:9/30/2014)...  Tasly Pharmaceuticals, Inc., the world,s leader in ... the launch of Deepure. Deepure is ... and women concerned with supporting their overall health ... while helping keep their health care cost down.  ... formulas, namely, ProHeart PLUS, ImmunoPower PLUS, and Pro-Memory ...
(Date:9/30/2014)... 2014 Aileron Therapeutics, Inc. - Product ... Markets Direct,s, ,Aileron Therapeutics, Inc. - Product Pipeline ... Aileron Therapeutics, Inc.,s pharmaceutical research and development focus. ... current therapeutic developmental pipeline of Aileron Therapeutics, Inc.,s, ... assessment by drug target, mechanism of action (MoA), ...
(Date:9/30/2014)... , September 30, 2014 ... research report the "Glycobiology/Glycomics Market by Product [Enzymes ... MALDI-TOF), Kits, and Reagents], Application (Immunology, Oncology) ... to 2019", published by MarketsandMarkets, provides a ... challenges, opportunities, current market trends, and strategies ...
Breaking Medicine Technology:Aileron Therapeutics, Inc. - Product Pipeline Review - 2014 2Aileron Therapeutics, Inc. - Product Pipeline Review - 2014 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 2Glycobiology / Glycomics Market Worth $928.11 Million by 2019 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 4
... Orally Dissolving Film StripBioAlliance to Resubmit Loramyc(R) NDA WOODCLIFF ... products division of a wholly owned subsidiary of Par ... provides an update on two of its pipeline products. ... 7, 2009, Strativa submitted a New Drug Application (NDA) ...
... April 8 Phase III data, published online this ... Metabolism , showed that arzoxifene, an investigational selective estrogen ... Company (NYSE: LLY ), significantly increased lumbar ... postmenopausal women with normal or low bone mass, versus ...
Cached Medicine Technology:Strativa Pharmaceuticals Provides Product Pipeline Update 2Strativa Pharmaceuticals Provides Product Pipeline Update 3Strativa Pharmaceuticals Provides Product Pipeline Update 4Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 2Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 3Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 4
... Comfort Pick one of our pipettors up ... trigger and ejector positionsright where they should beeven ... ergonomically designed to help avoid repetitive stress injuries ... In The Palm Of Your Hand Start ...
... Pick one of our pipettors up and ... and ejector positionsright where they should beeven if ... designed to help avoid repetitive stress injuries caused ... The Palm Of Your Hand Start dispensing ...
... total ergonomic solution and best value in ... touch action and ultra lightweight design reduce ... ejection with long, lever tip ejector , ... Accepts universal tips or for greater performance ...
... The Finnpipette BioControl multichannel ... features as the single ... handle fits allseven multichannel ... tip cone modules. Both ...
Medicine Products: