Navigation Links
Proteomics International biomarker study closer to a CDx test for diabetic kidney disease
Date:4/14/2014

April 2014, Perth, Australia. Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein biomarkers.

The research team authenticated the panel of biomarkers after taking 508 highly curated disease and control samples. Seven biomarkers were validated at high stringency using the company's proprietary mass spectrometry approach.

The mass spectrometry data was then cross-validated using immunoassays in collaboration with the KTH Royal Institute of Technology, Sweden, and Merck Millipore. A further five biomarkers were validated at high stringency and these are available for out-licensing. The validation was supported by a grant from Commercialisation Australia.

Proteomics International managing director Richard Lipscombe said there was excellent correlation between the new mass spectrometry platform and the traditional gold standard test, essential because antibody assays are more readily accepted by the FDA. "By doing it as a diagnostic and showing that the whole approach works, we set the foundations to create tests for other medical conditions," Dr Lipscombe said.

The next stage of development is to create a test that can determine whether patients will get diabetic kidney disease before they develop the condition. "The Holy Grail is to predict who's going to get sick and who isn't and that's something that will come out of our study later in 2014." Dr Lipscombe said. "But in the short term we want a diagnostic test that is going to provide doctors with a more accurate, robust test."

The International Diabetes Foundation estimates that there are 382 million people living with diabetes and expect the number to rise significantly. Based on current statistics 10 to 15 per cent of all people with diabetes will die from kidney disease.


'/>"/>

Contact: Dr. Roopwant Judge
roop@proteomics.com.au
Proteomics International
Source:Eurekalert

Page: 1

Related medicine news :

1. Global Proteomics Market (Instrumentation Technology, Reagents & Services) Worth $17.2 Billion by 2017 - New Report by MarketsandMarkets
2. New England Peptide, Inc. and Cambridge Isotope Laboratories, Inc. Announce Quantitative Proteomics Manufacturing Collaboration
3. Laboratory Automation Market: 2017 Equipment & Software, Drug Discovery, Clinical Diagnostics, Genomics & Proteomics Analysis in New Research Reports at RnRMarketResearch
4. Proteomics Market - Mass Spectrometry & Biochips 2017 Forecast & Analysis in New Research Report at ReportsnReports.com
5. The new age of proteomics: An integrative vision of the cellular world
6. Immunotherapy innovator wins 2014 Canada Gairdner International Award
7. Ottawa researcher receives international award for obesity research
8. Menopause International re-launching as Post Reproductive Health
9. International study shows majority of children unaware of cigarette warning labels
10. International Journal of Surgery affiliated with New York Surgical Society
11. Beaumont holds first international congress on underactive bladder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... ... May 25, 2016 , ... Dr. Travis Schwarz is an experienced dentist ... Road, O’Fallon, MO 63366. He serves patients of all ages with a full menu ... Schwarz’s success is reflected in the superior patient reviews that he has consistently earned ...
(Date:5/25/2016)... ... May 25, 2016 , ... DKT International, one of the ... is pleased to release their 2015 global impact data. In 2015, DKT served ... maternal deaths and 3.8 million unsafe abortions across 21 countries worldwide. , ...
(Date:5/25/2016)... ... May 25, 2016 , ... ... its annual Medical and Prescription Drug survey , an employee benefits ... survey, which was conducted in December 2015, indicates that employers are turning to ...
(Date:5/25/2016)... CA (PRWEB) , ... May 25, 2016 , ... "FCPX ... the quality of your footage," said Christina Austin - CEO of Pixel Film Studios. ... editors can quickly and easily add stylish color grades to their footage. A LUT ...
(Date:5/25/2016)... Atlanta GA (PRWEB) , ... May 25, 2016 ... ... workplace solutions builder, has announced that it will join America's leading engineers at ... will be held at the Georgia World Congress Center. , Engineers, speakers ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... Non-invasive diagnostic test realizes the ... ,Technology to be presented at Yissum’s booth, at IATI-BIOMED ... Company of the Hebrew University of Jerusalem announced ... Aurum Ventures MKI, the technology investment arm of Morris ... approach for early detection of multiple diseases by analyzing ...
(Date:5/23/2016)... -- Gamida Cell, a leader in cellular ... orphan genetic diseases, announced today it has been awarded ... Israel Innovation Authority (formerly the Office of the Chief ... The mission of the Israel Innovation Authority is to ... and technology, while stimulating economic growth. The ...
(Date:5/23/2016)... STAMFORD, Conn. , May 23, 2016 /PRNewswire/ ... Company has entered into an agreement with Egalet ... various patent claims. As part of the agreement ... rights, and will enable all three companies to ... abuse-deterrent properties. "This agreement reflects the ...
Breaking Medicine Technology: