Navigation Links
Proteomic profiling shown more accurate than traditional biomarkers in identifying liver cancer
Date:1/14/2008

BOSTON As the incidence of liver cancer continues to grow-- fueled in large part, by rising rates of hepatitis C infections so too does the need for tests to help diagnose the disease at an earlier stage. A study appearing in the January 15 issue of Clinical Cancer Research demonstrates that a novel mass-spectrometry based form of proteomic profiling is more accurate than traditional biomarkers in distinguishing liver cancer patients from patients with hepatitis C liver cirrhosis, particularly with regard to identifying patients with small, curable tumors. Led by researchers at Beth Israel Deaconess Medical Center (BIDMC), the study could help lead to earlier diagnostic methods and subsequent treatments -- for liver cancer.

Proteomics represents a potentially powerful tool for the serologic recognition of protein profiles associated with cancer, explains co-senior author Towia Libermann, PhD, Director of the Genomics Center at BIDMC and Associate Professor of Medicine at Harvard Medical School.

Although this particular proteomics technology, SELDI-TOF MS [surface enhanced laser desorption/ionization time of flight mass spectrometry] had already proven capable of identifying liver cancer in some limited studies, this was the first time that the technology was compared side-by-side with the clinical standard biomarker in a cohort of patients at risk for developing the disease, adds Liebermann, who is also Director of the Dana-Farber/Harvard Cancer Center Proteomics Core in the Division of Interdisciplinary Medicine and Biotechnology at BIDMC.

Over a single decade, the incidence of liver cancer (hepatocellular carcinoma) increased from 1.8 to 2.5 per 100,000 patients, in large part due to a rise in the spread of hepatitis C virus.

Hepatitis C has become a tremendous public health problem, explains co-senior author Nezam Afdhal, MD, Director of the Liver Center at BIDMC and Associate Professor of Medicine at Harvard Medic
'/>"/>

Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Story ideas from molecular & cellular proteomics
2. Genomic profiling of lung tumors helps doctors choose most effective treatment
3. Molecular profiling can accurately predict survival in colon cancer patients
4. Gene profiling can single out the worst cases of multiple myeloma and guide therapy
5. Mayo Clinic to Pilot Collexis Expert Profiling
6. MammaPrint(R) Breast Cancer Test Shown To Be Powerful Tool for Prognosis Prediction in Postmenopausal Breast Cancer Patients
7. Once-Daily Exjade(R) Shown to Remove Toxic Iron From the Heart and Liver, According to Data Presented at ASH
8. Wild Blueberries Shown to Fight Oxidative Stress
9. Video game shown to cut cortisol
10. Breaking Study: Masimo Pleth Variability Index (PVI) Shown Effective in Noninvasive Detection of Changes in Ventricular Preload and Fluid Volume
11. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/19/2013)... 6Webs.com is the leader in reviews ... are considering an alarm system can do a comparison ... security system providers online at 6Webs.com. Just recently finishing ... home security system companies, 6Webs.com currently is announcing ... home security companies before ranking the home security system ...
(Date:5/19/2013)... 19, 2013 Americans live closer to ... newest American Veterinary Medical Association (AVMA) U.S. Pet Ownership ... owners consider their dog a member of the family, ... as much five years earlier. , According to the ... the national income dedicated to pets has increased every ...
(Date:5/19/2013)... Los Angeles (PRWEB) May 19, 2013 Yeast ... infections can appear in sensitive areas of the human body. ... by Yeastrol. This new formula provides a unique method of ... This new spray solution is now provided to men and ... Yeast is naturally absorbed in the body through food and ...
(Date:5/19/2013)... Buenos Aires, Argentina: Yoga classes ( clases de Yoga ... by the Sivananda Yoga Vedanta Center. The center ... Norte). Classes are 90 minutes and are offered all ... a calm environment, allowing visitors to enjoy the benefits ... among others. , The Yoga classes follow the following ...
(Date:5/19/2013)... 2013 The Da Vinci robot lawyers ... in the nation’s first trial involving a Da Vinci ... State Superior Court, was filed by the widow of ... complications in a robot-assisted prostate removal, according to a ... robotic surgery lawsuit alleges those complication’s hastened his ...
Breaking Medicine News(10 mins):Health News:Top Rated DIY Home Security System Companies Published by 6Webs.com 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 3Health News:A Safe & Homeopathic Yeast Infection Relief by Yeastrol Now Available at HealthCareSupplementz.com with Massive Discount 2Health News:Clases de Yoga in Buenos Aires, Argentina (Yoga Classes) Now Offered by Sivananda Yoga Vedanta Center 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 3Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 4
... to experience 25% less muscle and joint pain in their ... study has also revealed that people who regularly participate in ... than non-runners even though they are more likely to suffer ... of the level of pain in a group of runners ...
... belief new studies point in the direction that a dose ... ,"High levels of daily stress are linked to a ... study carried out at the National Institute of Public Health, ... 18 years and asked about their routine levels of stress ...
... Compared to bare metal stents, placement of stents ... of the artery re-narrowing nine months following angioplasty ... to an article in the September 14 issue ... treatment of atherosclerotic coronary artery disease, according to ...
... on findings of a recent study researchers say that certain ... used to help current and former smokers ward off development ... worldwide. ,Researchers say their study provides significant insight ... by which the process can be slowed down after exposure ...
... early detection of breast cancer and the health officials recommend ... of the breasts for lumps every month for early diagnosis ... to start an early treatment which will give better treatment. ... England Journal of Medicine has shown that the newly developed ...
... has shown that there are few clinical comparisons available ... seeking the best individual drug for their children with ... to help make that choice. ,There are few ... relatively large variety of drugs prescribed for ADHD and ...
Cached Medicine News:Health News:Stents That Release Medication To Check Artery Narrowing 2Health News:Digital Mammogram For Detection Of Breast Cancer In Women With Dense Breasts 2Health News:Clinical Comparisons Between ADHD Drugs Are Less 2
(Date:5/17/2013)... Fla. , May 17, 2013 Fuse Science, ... delivery technology company that is developing new, patent-pending technologies poised ... announced today that it will hold a business update teleconference ... May 22 nd , 2013 at 4:30 PM ET. ... will host the call and will be joined ...
(Date:5/17/2013)... , May 17, 2013 Oramed ... of oral drug delivery systems, announced today that the ... the Company,s Investigational New Drug application(IND) for ORMD-0801, its ... to have the FDA clearance to proceed," stated ... upcoming trial is a major milestone for Oramed and ...
(Date:5/16/2013)... N.J. , May 16, 2013  PTC Therapeutics, ... statement on Form S-1 with the U.S. Securities and ... offering of its common stock. The number of shares ... offering have not been determined. (Logo:  ... Suisse are acting as joint book-running managers for the ...
Breaking Medicine Technology:Fuse Science, Inc. to Hold Business Update Webcast and Teleconference on May 22nd 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 3PTC Therapeutics, Inc. Files Registration Statement for Proposed Initial Public Offering 2
... provider of Telemedicine monitoring and diagnostic ... service commitment to patients and prescribing ... testing devices that provide enhanced diagnostic ... standard telephone lines. TransMedEx's product line ...
... Raytel Cardiac Services is a ... uniquely qualified people, combined with state-of-the-art ... clinical information that supports healthcare professionals ... Cardiac Services uses telecommunications and ECG ...
... has developed a new, integrated technology ... heartbeat-by-heartbeat, ECG monitoring, analysis and response, ... service is initially focused on helping ... arrhythmia. Time is of the essence ...
... microplate incubator is an extremely compact ... single microplate up to 50C. ... requiring higher temperatures up to 65C. ... low cost and high performance for ...
Medicine Products: