Navigation Links
Protein key to neuro-regeneration
Date:5/20/2008

Researchers at the Peninsula Medical School in the South West of England, University College London, the San Raffaele Scientific Institute in Milan and Cancer Research UK, have for the first time identified a protein that is key to the regeneration of damage in the peripheral nervous system and which could with further research lead to understanding diseases of our peripheral nervous systems and provide clues to methods of repairing damage in the central nervous system, according to a paper published this week in the Journal of Cell Biology.

The team looked at a protein called c-Jun, a transcription factor that regulates the expression of other genes. They found that the c-Jun protein plays a vital role in the regulating the plasticity of Schwann cells which is vital for the way in which the peripheral nervous system regenerates and repairs itself after injury.

Schwann cells produce the sheaths that surround and insulate neurons. When there is damage to the peripheral nervous system Schwann cells unwrap themselves from the degenerating axon. During this process of repair, Schwann cells then provide the correct environment for the neurons to re-grow and complete the process of repair.

By identifying this transcription factor, the research team believes that there is scope to produce eventual cures for damage and diseases of the peripheral nervous system, such as the inherited condition Charcot-Marie-Tooth disease and the autoimmune disorder Guillain-Barre disease.

Unlike the peripheral nervous system, the central nervous system does not regenerate when damaged. With further research, the team hopes to work towards identifying ways in which Schwann cells and c-Jun could be used to repair the spinal cord, leading to possible cures and relief for millions of people around the world suffering from damage of the central nervous system.

Further research could also identify whether abnormal activation of the c-Jun protein may be
'/>"/>

Contact: Andrew Gould
media@pr-works.co.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry
Source:Eurekalert

1

GOOD

Page: 1 2

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Penn study finds pro-death proteins required to regulate healthy immune function
3. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
4. Emory researchers identify signaling protein for multiple myeloma
5. Human C-reactive protein regulates myeloma tumor cell growth and survival
6. Lowering Blood Protein Wont Help Kidney Patients
7. Blood protein detects lung cancer, even at earliest stage
8. Natural Protein Could Help Spot, Treat Liver Cancer
9. Heat shock proteins are co-opted for cancer
10. How adhesive protein causes malaria
11. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... May 20, 2013 Idol lash has designed ... darker and fuller eyelashes in a matter of few weeks. ... online purchase with an extra pack offer to help more ... access this offer on the Idol lash official website. , ... increase the eyelash density up to 82% in just a ...
(Date:5/20/2013)... The Semi Truck Accident Victims Center ... service for an innocent victim of a catastrophic semi ... our services are unparalleled. What this means is if ... of a passenger vehicle involved in a semi truck ... Ohio, New Jersey, Indiana, Maryland, Georgia, Nebraska, Kansas, Michigan, ...
(Date:5/20/2013)... May 20, 2013 iGearUnlimited.com asked schools' technology ... case for students. The answers didn't surprise anyone: , 1. ... use and abuse, 2. Not too bulky – need to ... 3. Built-in kick-stand that works in both vertical and horizontal ... a trackable barcodes on each case, 5. Customizable – schools ...
(Date:5/20/2013)... Los Angeles, CA (PRWEB) May 20, 2013 ... 2013) – MessageSolution, an industry leader in enterprise-class ... of MessageSolution Enterprise eDiscovery Platform 7.0, the latest ... to address all facets of the legal discovery ... May 21-22 in Los Angeles CA. , As ...
(Date:5/20/2013)... you tell a joke well? , Do people roll their eyes ... to be funnier as a speaker, teacher, presenter of any kind? ... , Can't think of a snappy comeback when someone hits you ... you, don't worry. Help is here. I believe that ... learn to tell a joke well. I am not kidding. ...
Breaking Medicine News(10 mins):Health News:Idol Lash Eyelash Growth Enhancer Now Offered Extra Pack for Limited Time Only at HealthCareSupplementz.com 2Health News:Semi Truck Accident Victims Center Urges Family Members Of Victims Injured In A Horrific Semi Truck Accident In Any US State To Call Them First For An Unsurpassed Response 2Health News:New Rugged iPad Case for Bretford Charging Cart Saves the Day for School Deployments 2Health News:New Rugged iPad Case for Bretford Charging Cart Saves the Day for School Deployments 3Health News:MessageSolution Releases Enterprise eDiscovery Platform 7.0 at LegalTech 2013 West Coast Expo 2Health News:MessageSolution Releases Enterprise eDiscovery Platform 7.0 at LegalTech 2013 West Coast Expo 3Health News:MessageSolution Releases Enterprise eDiscovery Platform 7.0 at LegalTech 2013 West Coast Expo 4Health News:Psychologist Steve Wilson Gives A Dozen Tips to Help You Be More Humorous Even if You Can't Tell a Joke 2Health News:Psychologist Steve Wilson Gives A Dozen Tips to Help You Be More Humorous Even if You Can't Tell a Joke 3Health News:Psychologist Steve Wilson Gives A Dozen Tips to Help You Be More Humorous Even if You Can't Tell a Joke 4
... the lives of wild and laboratory rodents seems to throw ... exposed //to germs in the environment, rather than protecting against ... University analyzed the immune systems of mice and rats which ... ,Senior researcher William Parker said, "Laboratory rodents ...
... of subjecting drug addicts to shock therapy as a means ... controversies. Now, the Scottish Executive is doing more research into ... labeled as Neuro-Electric Therapy (NET) is executed with the use ... pulses are sent into the brain. This is known to ...
... A two year old, Stephen Carr’s life hangs between life ... acidosis, that requires //a double kidney transplant, which will give ... have the perfect match, so they will be donating a ... other children, said: "As parents we felt so helpless, especially ...
... Francisco Zoo had knowingly imported parakeets with a contagious and ... //. ,While the disease is not infectious cannot ... causes psittacine beak and feather disease could pose a threat ... system causing abnormal feather growth and beak deformities. No known ...
... flu virus found in poultry in Hungary last week was ... //. ,As chief veterinarian Miklos Suth said,‘This afternoon ... the highly pathogenic H5N1 strain of avian influenza which had ... report of the H5N1 virus in poultry in Hungary. ...
... Deadly H5N1 virus is been brought into New Zealand by ... ,At Wallaceville, country's highest security laboratory holds the threatening substance ... ,Joseph O'Keefe, the Wallaceville manager said it ... was kept inside a freezer. Well-trained staffs, wearing safe suits ...
Cached Medicine News:
(Date:5/16/2013)... NORTH CHICAGO, Ill. and MECHELEN, ... NV (Euronext: GLPG) and AbbVie (NYSE: ABBV ... development collaboration to include Crohn,s disease.  Galapagos will fund ... which is designed to facilitate rapid progression into Phase ... Q2 2015, AbbVie will pay Galapagos $50 million.  The ...
(Date:5/16/2013)... May 16, 2013  Today, the National Patient Advocate ... House of Representatives recently approved a bill that ... charging patients higher out-of-pocket fees for newer, more expensive ... which have more severe side-effects. However, the bill was ... which will continue to be a barrier to patients ...
(Date:5/16/2013)... THOUSAND OAKS, Calif. , May 16, 2013  Amgen ... Global Life Sciences Conference on Tuesday, May 21, 2013, at ... York City , beginning at 10:00 a.m. Eastern Daylight ... senior vice president of Research and Development at Amgen, will ... be accessed from the Events Calendar on Amgen,s website, ...
Breaking Medicine Technology:AbbVie and Galapagos Extend GLPG0634 Collaboration to Include Crohn's Disease 2AbbVie and Galapagos Extend GLPG0634 Collaboration to Include Crohn's Disease 3AbbVie and Galapagos Extend GLPG0634 Collaboration to Include Crohn's Disease 4AbbVie and Galapagos Extend GLPG0634 Collaboration to Include Crohn's Disease 5AbbVie and Galapagos Extend GLPG0634 Collaboration to Include Crohn's Disease 6National Patient Advocate Foundation Responds to N.C. State House Approval of Flawed Cancer Treatment Fairness Bill 2National Patient Advocate Foundation Responds to N.C. State House Approval of Flawed Cancer Treatment Fairness Bill 3
... Corporation (Nasdaq: KNSY ) announced today that it ... facility with Wells Fargo Bank, National Association. The ... on May 25, 2014, with the option to extend it ... conditions. The credit facility allows the Company to use borrowings ...
... Savient Pharmaceuticals, Inc. (Nasdaq: SVNT ) ... filed by its wholly owned subsidiary, Savient Pharma ... the treatment of chronic gout in adult patients ... the European Medicines Agency (EMA).  The MAA has ...
Cached Medicine Technology:Savient Pharmaceuticals Marketing Authorization Application for KRYSTEXXA® Accepted for Review by European Medicines Agency 2Savient Pharmaceuticals Marketing Authorization Application for KRYSTEXXA® Accepted for Review by European Medicines Agency 3Savient Pharmaceuticals Marketing Authorization Application for KRYSTEXXA® Accepted for Review by European Medicines Agency 4
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... Our breadth of infectious disease ELISA ... field. With standard assay protocols for faster ... Disease ELISA products provide increased reliability and ... includes antibody detection assays for a wide ...
... a complete line of enteric ... monoclonal and monoclonal/polyclonal antibody-based ELISA ... enteric pathogens in fecal specimens. ... Clostridium difficile, Entamoeba histolytica, Giardia, ...
Inquire...
Medicine Products: