Navigation Links
Protein involved in cystic fibrosis also plays role in emphysema, chronic lung disease
Date:12/29/2010

rchers used two types of ceramide inhibitors to treat mice with lung damage caused by a bacterial infection. One of the inhibitors, FB1, successfully decreased ceramide buildup in mice with intact CFTR but failed to stop ceramide accumulation in mice with absent CFTR, as is the case in CF. However, the other type of inhibitor, AMT, curbed ceramide activity in the mice with the absent CFTR, while failing to do so in those with decreased CFTR.

"Each inhibitor appeared to be effective based on the levels of membrane CFTR and ceramide, suggesting two different therapies tailored to treat lung damage stemming from two distinct lung disorders emphysema and CF," said co-investigator Manish Bodas, Ph.D., a post-doctoral fellow in Vij's lab at Hopkins Children's.


'/>"/>

Contact: Ekaterina Pesheva
epeshev1@jhmi.edu
410-516-4996
Johns Hopkins Medical Institutions
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. New and Delicious, Almond Butter Filled, Cookie Bites With 35.7% Protein to Help Manage Weight and Build Muscle
2. Research highlights role of protein pair in obesity regulation
3. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
4. Smithfield, United Food and Commercial Workers Union, and Food Networks Paula Deen to Deliver 150,000 Servings of Protein to San Francisco Food Bank
5. Protein Sciences Corporation Announces Profitable and Cash Flow Positive Results for 2009 and Management Realignment
6. Protein Appears Key to Intestinal Balance
7. SIBLING proteins may predict oral cancer
8. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
9. Cells of aggressive leukemia hijack normal protein to grow
10. Omega Protein Comments on California Lawsuit Alleging Fish Oil Contaminants
11. Proteins May Predict Spread of Colon Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein involved in cystic fibrosis also plays role in emphysema, chronic lung disease
(Date:3/27/2015)... (PRWEB) March 27, 2015 The ... Germany” is an essential source of information on ... landscape in Germany. Germany’s increasingly elderly population and ... its pharmaceutical market. In 2013, the elderly accounted ... increase at Compound Annual Growth Rate (CAGR) of ...
(Date:3/27/2015)... PRUSSIA, PA and LONDON, UK (PRWEB) March 27, 2015 ... President of DrugDev SiteStart Melissa (Liss) Easy was named ... , The 40 Under 40 list spotlights 40 ... for their professional accomplishments and community involvement. Winners are ... in a special supplement of the Philadelphia Business Journal. ...
(Date:3/27/2015)... 27, 2015 According to Health ... born with Neonatal Abstinence Syndrome (NAS) are causing alarm ... the painful withdrawal process for a month of their ... crying, diarrhea, and vomiting. The condition is precipitated by ... alcohol addiction treatment (and employing medically assisted drug treatment) ...
(Date:3/27/2015)... California’s ongoing worst ever drought, and the ... United States Northeast, are both manifestations of the same ... creating changes in the atmosphere’s “energy balance,” according to ... researcher, speaking on the Sharon Kleyne Hour™ Power of ... warmer and dryer global climate but also greater and ...
(Date:3/27/2015)... Atlanta, Georgia (PRWEB) March 27, 2015 To ... and shade issues, Super-Sod spent a year filming this video ... lawn needs and the shady environment it's often expected to ... shade. , All plants need light to survive. Anytime a ... essentially being put on a diet. Many homeowners try to ...
Breaking Medicine News(10 mins):Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 2Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 3Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 4Health News:DrugDev Founder Melissa Easy is 2015 Philadelphia Business Journal 40 Under 40 Honoree 2Health News:In Florida Only 10% of Pregnant Mothers Are Referred to Drug Rehab Despite Testing Positive for Narcotics 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 3Health News:For Spring Turf Planting Season, Super-Sod Created a New How-To Video Entitled "Two Views on Shade and Turf" 2
... diabetic pregnancies have a greater risk of childhood obesity, ... Health shows breastfeeding can reduce this threat. Epidemiologist ... children of diabetic pregnancies and 399 of non-diabetic pregnancies ... of breastfeeding on the growth of body mass index ...
... News) -- Middle-school kids who participate in lots of sports ... research finds. Yet, students with teammates who smoke are ... is more pronounced among girls. "This result suggests that ... even though there might be a protective effect overall of ...
... FRANCISCO There is growing evidence that supports an association between ... thigh bone, typically without trauma and the use of ... incidence caused by osteoporosis. While the risk for suffering an ... just 1 in 1,000 patients after six years of ...
... 7, 2012). Researchers at Virginia Commonwealth University Medical ... Young Neurosurgical Center (Richmond, VA) and Old Dominion ... Wilms tumor 1 protein (WT1) results in downregulation ... lines and reduces the characteristic invasiveness exhibited by ...
... MONDAY, Feb. 6 (HealthDay News) -- ,When it comes ... of defense is lifestyle changes such as losing weight and ... get blood sugar levels under control, the American College of ... treatment that should be given. If metformin alone ...
... forests, fields, rivers -- and thereby on humans that breathe, ... comprehensive comparison of computer-based simulations from all over the world ... from ecosystems to agriculture to water supplies and health will ... be provided by more than two dozen research groups from ...
Cached Medicine News:Health News:Breastfeeding can reduce risk of childhood obesity 2Health News:Halting bone-building osteoporosis drug use cuts risk for additional atypical femur fracture in half 2Health News:CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness 2Health News:CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness 3Health News:Metformin Preferred Drug for Type 2 Diabetes, Experts Say 2Health News:Metformin Preferred Drug for Type 2 Diabetes, Experts Say 3Health News:Quantifying climate impacts: New comprehensive model comparison launched 2Health News:Quantifying climate impacts: New comprehensive model comparison launched 3
(Date:3/27/2015)... 2015 Dynatronics Corporation (NASDAQ: DYNT ) today ... to the Company,s Board of Directors effective March 23, 2015, ... 2014 of board member Joseph Barton .  ... Board of Directors represents an important step forward for the ... of Dynatronics.  "Rich is a proven leader and is well-known ...
(Date:3/27/2015)... 27, 2015 The Temple Health & Bioscience District ... 5,000-square-foot building at 1802 South First St. in the Temple ... the City of Temple to receive ... the Central Texas Veterans Health Care System, the new facility ... early stage biotechnology and life science companies. ...
(Date:3/27/2015)... 2015 XRpro Sciences, Inc., a provider ... development services which features high throughput transporter and ... financial results for the year ended December 31, ... of XRpro Sciences commented, "We have completed a ... stage to commercial stage in large part by ...
Breaking Medicine Technology:Dynatronics Announces Appointment of Richard J. Linder to Board of Directors 2Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2XRpro Sciences Announces Fiscal 2014 Financial Results 2XRpro Sciences Announces Fiscal 2014 Financial Results 3XRpro Sciences Announces Fiscal 2014 Financial Results 4
... 21, 2011 VIVUS, Inc. (Nasdaq: VVUS ) ... Food and Drug Administration (FDA) for the New Drug Application ... obesity.  The meeting occurred on January 19th at the FDA,s ... the FDA and VIVUS, management and consultants.  At this meeting ...
... held) today announced that they have signed a multi-year ... clear, and manufacture assays for the Abbott Molecular FDA ... terms have not been disclosed. IMDx ... evolving clinical needs. The tests are designed utilizing IMDx,s ...
Cached Medicine Technology:VIVUS Provides Regulatory Update on QNEXA NDA 2VIVUS Provides Regulatory Update on QNEXA NDA 3Intelligent Medical Devices, Inc. (IMDx) Enters into an Agreement with Abbott for the Distribution of a Broad Menu of Molecular Tests 2
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
CCR Medical conventional laryngoscopes....
CCR Medical conventional laryngoscope handles....
... The Intubating LMA™ Airway. , ... or unexpected difficult airway, the LMA Fastrach™ ... without moving the head or neck. The ... attempts. , ,Selected by emergency teams ...
Medicine Products: