Navigation Links
Protein in prostate biopsies signals increased cancer risk
Date:12/3/2013

NEW YORK (December 3, 2013) -- Researchers from Weill Cornell Medical College have shown that the presence of a particular protein in biopsied prostate tissue substantially increases the likelihood that cancer will develop in that organ. The discovery will likely help physicians decide how closely to monitor men potentially at risk for the cancer -- among the most confusing and controversial dilemmas in health care.

Their findings, reported in the Journal of Clinical Oncology, are the first to quantify, in the setting of a clinical trial, the increased risk of prostate cancer development from the protein ERG.

Traditional means of determining risk of prostate cancer -- blood tests for the protein prostate-specific antigen (PSA) and biopsies -- do not always correlate well with the chances of dying from the disease. Decisions on what to do with the results of these tests can be unclear, leaving doctors and patients frustrated and unsure of how to proceed.

Researchers at Weill Cornell Medical College are looking at specific changes within prostate cells, from an initial biopsy, to determine which men have a higher risk of prostate cancer development and need repeat biopsies or other types of monitoring. This study starts to fill in the picture for about 10 percent of prostate biopsies.

Investigators found that 53 percent of men whose prostate biopsies showed expression of ERG protein developed invasive prostate cancer, compared to 35 percent of men whose biopsies were ERG-negative. All of the biopsies were classified as having high-grade prostatic intraepithelial neoplasia (HGPIN), which are lesions that may or may not morph into cancer.

The findings mean that potentially thousands of men a year -- those with ERG-positive HGPIN biopsies -- may benefit from increased surveillance and early treatment of prostate cancer, while those whose HGPIN biopsies come back ERG-negative may be able to avoid unnecessa
'/>"/>

Contact: Sarah Smith
sas2072@med.cornell.edu
646-317-7401
Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Warwick scientists uncover how checkpoint proteins bind chromosomes
2. Specific protein triggers changes in neurons in brain reward center linked to cocaine addiction
3. Unusual protein helps regulate key cell communication pathway
4. Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor
5. RANK protein promotes the initiation, progression and metastasis of human breast cancer
6. Protein may represent a switch to turn off B cell lymphoma
7. Protein RAL associated with aggressive characteristics in prostate, bladder and skin cancers
8. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
9. Pivotal role for proteins -- from helping turn carbs into energy to causing devastating disease
10. New molecular structure offers first picture of a protein family vital to human health
11. Wayne State University researcher examines proteins role in diabetic retinopathy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Gray HealthDay Reporter WEDNESDAY, ... rare, colds, flu and other minor infections might trigger a ... children, a new study suggests. Just five out of ... States, said Dr. Heather Fullerton, lead author of the study ... of California, San Francisco Benioff Children,s Hospital. "It seems infections ...
(Date:8/20/2014)... August 20, 2014 The Board of ... Perkins Eastman is pleased to announce the expansion ... in China and the surrounding region. In ... Richard Sprow AIA has relocated to the firm’s ... in healthcare planning and design and to better support ...
(Date:8/20/2014)... With 3943.8% growth, Connexion Point ranks number 86 ... growing companies. The Inc. 500 ranks Connexion Point 12th, nationally, ... is the #1 fastest growing company in Utah. , Connexion ... its clients include four of the top 10 health care ... has offices and contact centers in Salt Lake City, Provo, ...
(Date:8/20/2014)... In contrast to evidence that the amygdala stimulates ... Primate Research Center, Emory University have found that ... hormones during the early development of nonhuman primates. ... Journal of Neuroscience . , The amygdala ... be important for responses to threatening situations and ...
(Date:8/20/2014)... New research reveals that, long ago, sea mammals may ... the infectious disease known as tuberculosis. Ancient strains ... and sea lions, who then spread it to people ... an international team of researchers. "Tuberculosis is a ... study and further research will help us understand how ...
Breaking Medicine News(10 mins):Health News:Study Ties Colds, Flu to Rare Risk of Stroke in Kids 2Health News:Study Ties Colds, Flu to Rare Risk of Stroke in Kids 3Health News:Perkins Eastman Expands Presence in China 2Health News:Perkins Eastman Expands Presence in China 3Health News:With 3943.8% Growth, Connexion Point, a Leader in Contact Centers for Health Care, Ranks 86th on the Inc. 500 List as One of the Nation’s Fastest Growing Companies 2Health News:Maturing brain flips function of amygdala in regulating stress hormones 2Health News:Maturing brain flips function of amygdala in regulating stress hormones 3Health News:Seals, Sea Lions Helped Global Spread of TB, Study Finds 2
... 12 /Xinhua-PRNewswire-FirstCall/ -- China,Medicine Corporation ("CMC") ... of prescription and over the counter ... made of Chinese herbs),Chinese herbs, nutritional ... formulations today announced the Company,s ADTZ,(Aflatoxin-detoxifizyme) ...
... reveal more damage compared to sporadic cases , FRIDAY, Oct. ... appears to cause more severe brain damage than the non-familial ... scans to examine the brains of 759 MS patients and ... more destructed lesions, and significantly lower volume of whole brain, ...
... for lowering cholesterol and maybe even fighting dementia, and ... slow decline in lung function in the elderly even ... it may be statins anti-inflammatory and antioxidant properties that ... in the second issue for October in the American ...
... WESTFIELD, N.J., Oct. 12 Don,t hire an ad agency; ... great marketing,ideas. It is not because an agency can,t come ... options to uncover new marketing ideas. Most clients follow ... out an RFP, interview agencies, then develop a,short list of ...
... CHICAGO, Oct. 11 Continuing its efforts ... SAVE THE PATIENT, a,not-for-profit patient-focused organization, is hosting ... Network. "Community Health Hotline" will,air Monday, October 15, ... Monday,s program will feature a frank discussion on ...
... 11 /Xinhua-PRNewswire/ -- On,October 10, 2007, Synutra International, ... of dairy-based nutritional products,for infants, children and adults, ... that the Company,s common stock is no longer ... on October 5, 2007 of the,Company,s quarterly report ...
Cached Medicine News:Health News:China Medicine's ADTZ Project Has Been Selected as One of Six Patent Commercialization Projects in Guangdong Province 2Health News:Familial MS May Be More Destructive 2Health News:Statins reduce loss of function, keeping old lungs young - even in smokers 2Health News:A New Way to Discover Marketing Ideas 2Health News:Patient Empowerment -- Medication Error 2Health News:Nasdaq Informs Synutra that the Company's Filing Delinquency has been Cured 2
(Date:8/20/2014)... 2014 Reportlinker.com announces that a new ... Global Coatings for Medical Devices Industry ... This report analyzes the worldwide markets for ... the following Product Segments: Active Coatings, Protective Coatings, ... separate comprehensive analytics for the US, ...
(Date:8/20/2014)... SALT LAKE CITY , Aug. 20, 2014 /PRNewswire/ ... their revolutionary mobile diagnostic platform during a special event ... City, Utah , on September 5, 2014. The ... be LiveStreamed on the ApolloDx website, www.apollodx.com .  ... will transform diagnostic testing," said Jared Bauer , ...
(Date:8/20/2014)... --  Easy Breathe , the fastest growing online sleep apnea ... - has received more than 4.5 million unique page views since ... that so many people are finding our blog and reading our ... committed to making sleep apnea more widely known and hope that ... sleep apnea news , troubleshooting advice , and new ...
Breaking Medicine Technology:Global Coatings for Medical Devices Industry 2Global Coatings for Medical Devices Industry 3Global Coatings for Medical Devices Industry 4Global Coatings for Medical Devices Industry 5Global Coatings for Medical Devices Industry 6Global Coatings for Medical Devices Industry 7Global Coatings for Medical Devices Industry 8Global Coatings for Medical Devices Industry 9Global Coatings for Medical Devices Industry 10Global Coatings for Medical Devices Industry 11Global Coatings for Medical Devices Industry 12Global Coatings for Medical Devices Industry 13Global Coatings for Medical Devices Industry 14Global Coatings for Medical Devices Industry 15Global Coatings for Medical Devices Industry 16Global Coatings for Medical Devices Industry 17Global Coatings for Medical Devices Industry 18Global Coatings for Medical Devices Industry 19Global Coatings for Medical Devices Industry 20Global Coatings for Medical Devices Industry 21Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4
Inquire...
Inquire...
Contour I pouches are light as a feather and feature our tapered SoftFlex skin barrier for comformability, flexbility and comfort. All Contour I pouches have ComfortWear panels that keep skin cool an...
Inquire...
Medicine Products: