Navigation Links
Protein in human hair shows promise for regenerating nerves
Date:1/10/2008

tin affects the activity of Schwann cells, which play a vital role in nerve regeneration. These cells produce signals that tell nerve cells to begin regenerating and remodel the blood clot that has formed so that nerve cells can grow across it.

By using keratin to activate these cells, were trying to tap into the natural healing cascade, said Van Dyke. We believe that keratin helps amp up Schwann cell activity and give the nerve regeneration process a head start.

The laboratory studies showed that keratin activated Schwann cells and increased their proliferation and migration. Next, the scientists used a keratin-filled tube to attempt to repair a 4 millimeter nerve gap in mice -- a fairly significant gap considering the size of the animal.

The results from these animals were compared with animals treated with an empty nerve guidance conduit and with animals treated with a nerve graft.

After six weeks, 100 percent of the animals in the keratin and nerve graft groups showed visible nerve regeneration across the gap, compared to only 50 percent who got the empty conduit. The speed of repair was best in the keratin group.

The scientists then tested the function of the regenerated nerve. The speed of nerve impulses was best in the keratin group. The amount of signal that got through the nerve was better in the keratin group than in the empty tube group. The study was recently highlighted in the journal Science.

The results suggest that a conduit filler derived from hair keratins can promote an outcome comparable to a grafted nerve, said Van Dyke.

In the study, the nerve function did not translate into recovery of muscle function, but the scientists suspect they may have tested too early, before the nerve had time to regenerate to the muscle. It is known that muscle function recovery lags behind nerve recovery. Future studies will focus on regeneration across larger gaps and will test whether nerve regenera
'/>"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Protein power: Researchers trigger insulin production in diabetic mice
2. Protein Nasal Spray Revives Sleep-Deprived Monkeys
3. Protein a possible key to allergy and asthma control
4. Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
5. Receptor protein appears to be key in breakdown of kidney filtration
6. Protein-dependent switch regulates intracellular trafficking in epithelial cells
7. Researchers led by Penn vet uncover the delicate protein balance behind the immune system response
8. Extracellular protein sensitizes ovarian cancer cells to chemotherapy
9. St. Jude Finds Mechanism for Faulty Protein Disposal
10. St. Jude finds mechanism for faulty protein disposal
11. Brain Protein May Be a Clue to Autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... of your worst memories? How did it make you ... a negative personal experience, such as how sad you ... emotional distress, especially when you can,t stop thinking about ... thinking about the context of the memories, rather than ... way to alleviate the negative effects of these memories, ...
(Date:4/18/2014)... ― A new study in the American Journal ... Google searches reveals a recurring pattern that could be ... Investigators from San Diego State University, the Santa Fe ... "healthy" Google searches (searches that included the term healthy ... the U.S. from 2005 to 2012. They found that ...
(Date:4/17/2014)... of chronic inflammation in benign prostate tissue was ... this association was found even in those with ... study published in Cancer Epidemiology, Biomarkers & ... for Cancer Research. , An analysis of prostate ... placebo arm of the Prostate Cancer Prevention Trial ...
(Date:4/17/2014)... that could be used to provide relief from ... made the discovery when researching how pain occurs ... , Dr Marzia Malcangio said: "We have been ... our findings could help chemotherapy patients who suffer ... effect of some chemotherapy drugs (such as vincristine) ...
(Date:4/17/2014)... Experimental Biology and Medicine a multidisciplinary ... Paul Kenis in the Institute of Genomic Biology ... Illinois Urbana-Champaign describe their recent work on subcellular ... of cell functions including energy metabolism, signaling, and ... regulating normal cellular behavior, redox status has been ...
Breaking Medicine News(10 mins):Health News:New study suggests a better way to deal with bad memories 2Health News:New study suggests a better way to deal with bad memories 3Health News:New research shows people are thinking about their health early in the week 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 3Health News:New pain relief targets discovered 2Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2
... the Hebrew University of Jerusalem have discovered that Vav1 ... one of the factors in tumorous tissue growth -- plays ... previously been thought. The discovery has implications for further concentration ... work of the researchers, led by Dr. Shulamit Katzav-Shapira of ...
... 2010) International experts and scientists will present ... life of stockpiled drugs to identifying unlabeled substances ... of the 2010 International Pharmaceutical Federation (FIP) Pharmaceutical ... American Association of Pharmaceutical Scientists (AAPS) Annual Meeting ...
... , MONDAY, Nov. 8 (HealthDay News) -- A new ... can be inherited. As part of the Framingham Foot ... participants between 2002 and 2005, researchers studied 675 people ... towards the smaller toes (known as hallux valgus), and 154 ...
... an electrical switch allows the flow of electricity into electrical ... optical switch allowing the flow of light through otherwise opaque ... Los Alamos National Laboratory delivers a 200 terawatt power pulse ... States) in half a trillionth of a second (picosecond) time. ...
... study suggests joint complaints attributed to aromatase inhibitors (AI), ... arthritis or autoimmune disease. Because of that, researchers ... of arthritis should be encouraged to continue taking the ... Tuesday, Nov. 9 at the 74th Annual Scientific Meeting ...
... GA Lupus puts children at higher risk for ... using statins doesn,t provide enough benefit to warrant their ... largest study of pediatric lupus patients to date. ... and organ damage. Children with lupus show early signs ...
Cached Medicine News:Health News:Hebrew University researchers discover expanded role for cancer-causing gene 2Health News:Common Foot Disorders Can Be Inherited, Research Shows 2Health News:Plasma as a fast optical switch 2Health News:Joint pain linked to breast cancer drug not inflammatory arthritis or autoimmune disease 2Health News:Statins don't prove useful for general pediatric lupus population 2
(Date:1/14/2014)... 14, 2014 The Brandeis Medical Center, led by Dr. ... premier and affordable laser tattoo removal experience with the advanced Astanza ... in providing high quality cosmetic services with cutting edge medical technology ... Southern California has seen a dramatic increase in ...
(Date:1/14/2014)... Animal Emergency Critical Care, a LifeCentre partner practice, located at 165 ... the first in Loudoun County to receive ... Susan M. Barnes , Medical Director, is a well-seasoned veterinarian of ... Taylor , are avid scuba divers. "As altitude skiers and hikers, ...
(Date:1/14/2014)... N.Y. , Jan. 14, 2014   Oligomerix, Inc. , ... modifying therapeutics for Alzheimer,s disease (AD) and related neurodegenerative ... to Valhalla, NY as of ... laboratory space at New York Medical College. ...
Breaking Medicine Technology:Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... March 7, 2012  Solta Medical, Inc. (NASDAQ: ... market, today provided an update on the launch of ... approved by the FDA. A majority ... comprised of leading plastic surgeons and dermatologists, who received ...
...  Discovery Laboratories, Inc. (NASDAQ: DSCO ), a ... in respiratory critical care, will hold a conference call ... its March 6th announcement that SURFAXIN (lucinactant) has been ... Distress Syndrome (RDS) in premature infants at high risk ...
Cached Medicine Technology:Solta Medical Provides Update on Liposonix Launch 2Solta Medical Provides Update on Liposonix Launch 3Solta Medical Provides Update on Liposonix Launch 4Media Alert: Discovery Labs to Hold Conference Call to Discuss FDA Approval of SURFAXIN® (lucinactant) 2
Eliminate preanalytical errors with automated QC module....
Non-invasive and continuous tcpCO2 and tcpO2 patient monitoring....
... Submit your analyzer data via the ... a worldwide peer group. , ... you to perform statistical analysis of ... often as you like. Peer-group data ...
Automated QC module...
Medicine Products: