Navigation Links
Protein in Breast Tumors May Predict Chemo Response
Date:3/26/2010

Study suggests identifying substance can lead to more accurate diagnosis,,

FRIDAY, March 26 (HealthDay News) --The presence of a substance in breast cancer tumors can help doctors predict how people will respond to chemotherapy, German researchers have found.

"The relationship to total response was remarkable," Gunter von Minckwitz, leader of a team that is studying the substance, known as protein poly (ADP-ribose) polymerase, or PARP, said in a news release from the European Breast Cancer Conference.

"Tumors with a high level of PARP expression had a total response in 26 percent of cases, whereas those tumors which did not express PARP had a total response in only 9 percent," said von Minckwitz, who is chairman of the German Breast Group.

"Additionally," he said, "we found that the presence of PARP can provide more accurate prognostic information than the grade of differentiation or degree of abnormality of tumors."

The researchers, who studied 646 women with breast cancer, found that PARP isn't just linked in some tumors but is connected to all breast cancer subtypes.

According to the researchers, PARP plays a variety of roles in cellular processes. Among other things, they said, it helps repair breaks in DNA.

The study findings were to be presented Friday at the European Breast Cancer Conference in Barcelona, Spain.

More information

Breastcancer.org has more on chemotherapy for breast cancer.



-- Randy Dotinga



SOURCE: European Breast Cancer Conference, news release, March 26, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Tumors Use a Protein to Hide From Immune System
2. Newly identified proteins critical to FA pathway DNA repair function
3. Proteins may point to alcohol use test
4. Blocking Protein May Stem COPD
5. Whey Protein Pioneers Announce The World's Best Tasting Protein Powder
6. Omega Protein Reports 2009 Results
7. K-State professor finds link between low oxygen levels in body and cancer-aiding protein
8. Proteins May Predict Spread of Colon Cancer
9. Omega Protein Comments on California Lawsuit Alleging Fish Oil Contaminants
10. Cells of aggressive leukemia hijack normal protein to grow
11. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016  Collagen Matrix, Inc., ("Collagen Matrix") the ... of collagen and mineral based medical devices for ... Bill Messer has joined the company as ... the growing portfolio of oral surgery, neurosurgery, orthopaedic ... joins the Collagen Matrix executive team as an ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
Breaking Medicine Technology: