Navigation Links
Protein in Breast Tumors May Predict Chemo Response

Study suggests identifying substance can lead to more accurate diagnosis,,

FRIDAY, March 26 (HealthDay News) --The presence of a substance in breast cancer tumors can help doctors predict how people will respond to chemotherapy, German researchers have found.

"The relationship to total response was remarkable," Gunter von Minckwitz, leader of a team that is studying the substance, known as protein poly (ADP-ribose) polymerase, or PARP, said in a news release from the European Breast Cancer Conference.

"Tumors with a high level of PARP expression had a total response in 26 percent of cases, whereas those tumors which did not express PARP had a total response in only 9 percent," said von Minckwitz, who is chairman of the German Breast Group.

"Additionally," he said, "we found that the presence of PARP can provide more accurate prognostic information than the grade of differentiation or degree of abnormality of tumors."

The researchers, who studied 646 women with breast cancer, found that PARP isn't just linked in some tumors but is connected to all breast cancer subtypes.

According to the researchers, PARP plays a variety of roles in cellular processes. Among other things, they said, it helps repair breaks in DNA.

The study findings were to be presented Friday at the European Breast Cancer Conference in Barcelona, Spain.

More information has more on chemotherapy for breast cancer.

-- Randy Dotinga

SOURCE: European Breast Cancer Conference, news release, March 26, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Tumors Use a Protein to Hide From Immune System
2. Newly identified proteins critical to FA pathway DNA repair function
3. Proteins may point to alcohol use test
4. Blocking Protein May Stem COPD
5. Whey Protein Pioneers Announce The World's Best Tasting Protein Powder
6. Omega Protein Reports 2009 Results
7. K-State professor finds link between low oxygen levels in body and cancer-aiding protein
8. Proteins May Predict Spread of Colon Cancer
9. Omega Protein Comments on California Lawsuit Alleging Fish Oil Contaminants
10. Cells of aggressive leukemia hijack normal protein to grow
11. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
Post Your Comments:
(Date:10/13/2017)... ... October 13, 2017 , ... ... Arkansas that offers insurance and financial preparation services, is providing an update on ... Rescue organization. , Rock City Rescue is a locally recognized nonprofit that provides ...
(Date:10/13/2017)... Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD ... dose required and providing a CBD form that can be easily incorporated into liquid ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset ... of specialty vendors and unique items from across the nation, this holiday-themed event will ... services offered by the VNA. The boutique will be open Saturday, November 4 ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Planet Fitness, ... the U.S., announced today its plans to open a flagship location in Covington, LA ... the former Rooms To Go store next to Office Depot in the Holiday Square ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading ... announced that its MyDario product is expected to appear on The Dr. ... The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The Dr. Oz Show ... The segment ...
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical (AVACEN) ... is now successfully helping those with the widespread pain ... Fibromyalgia diagnosed Amanda in Essex, England ... washing my hair, experiencing no sleep at all, tremendous ... spasm… I cannot recommend [the AVACEN 100] enough, how ...
(Date:9/13/2017)... has been named the official orthopedic and sports medicine ... 2018 College Football Playoff (CFP) National Championship to be played ... Atlanta, Georgia . OrthoAtlanta is proud to be ... many activities leading up to, and including the national championship ... OrthoAtlanta serves ...
Breaking Medicine Technology: