Navigation Links
Protein helps parasite survive in host cells
Date:12/28/2010

of host proteins known as immunity-related GTPases. Tests in cell cultures and animal models showed that this binding leads to a reaction that disables the GTPases, which normally would rupture the parasite's protective membrane.

"With one exception, humans don't have the same family of immunity-related GTPases," Fentress notes. "But we do have a similar group of immune recognition proteins called guanylate-binding proteins, and we are currently testing to see if ROP18 deactivates these proteins in human cells in a similar manner."

The findings could be applicable to other parasites and pathogens. Toxoplasmosis belongs to a family of parasites that includes the parasite Plasmodium, which causes malaria. All surround themselves with protective membranes when they enter host cells.

"Plasmodium doesn't make ROP18, but it does secrete related proteins called FIKK," says Fentress. "It's possible they also act to thwart host defense mechanisms like GTPases and guanylate-binding proteins."


'/>"/>

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Human protein improves muscle function of muscular dystrophy mice
2. UCLA researchers uncover new cell biological mechanism that regulates protein stability in cells
3. Protein disables p53, drives breast cells toward cancer transition
4. Protein offers new clue to cause and treatment for kidney disease
5. Protein targeted to stop melanoma tumor growth
6. New Test Links Blood Protein to Heart Disease, Diabetes Risk
7. Scientists Find Protein That May Help Control Prostate Cancer
8. Neurological protein may hold the key to new treatments for depression
9. More Protein, Fewer Refined Carbs May Keep Weight Off
10. Protein found to predict brain injury in children on ECMO life support
11. Protein in the urine: A warning sign for cognitive decline
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein helps parasite survive in host cells
(Date:4/26/2015)... (PRWEB) April 26, 2015 With the FCPX ... Pro X editors can quickly and easily add desaturated ... that contains a mathematical formula for modifying an image. The ... by the table. This pack comes with 60 black and ... vintage and contemporary black and white films. With the ...
(Date:4/26/2015)... 2015 In an article published last ... the head-neck biomechanics occurring during the use of handheld electronic ... to determine that use of a tablet increases mechanical demand ... times - more than when the neck is in a ... study, but pointing out the potential hazards of overuse of ...
(Date:4/25/2015)... 2015 Diversified Communications has announced ... event. The Integrative Healthcare Symposium Canada, as it’s ... at the Sheraton Parkway Toronto North in Ontario. ... of the most anticipated events of the year ... program. The event aims to gather multi-disciplined practitioners ...
(Date:4/25/2015)... 25, 2015 The federal multidistrict ... lawsuits filed against C.R. Bard, Inc. continues to ... District of West Virginia. According to a Pretrial ... convened that day, after certain defendants submitted amended ... The Order directed that any Preliminary Motions referenced ...
(Date:4/25/2015)... Gardant Management Solutions will lead sessions ... and sales and marketing at the LeadingAge Illinois ... held from April 29 through May 1 in ... eldercare association in Illinois. The statewide association represents ... including senior housing, assisted living and supportive living ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios, a FCPX Effects Developer, Announced the Release of FCPX LUT B&W 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4Health News:Integrative Healthcare Event launching in Canada 2Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 2Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 3Health News:C.R. Bard Vaginal Mesh Lawsuit News: Federal Litigation Issues New Pretrial Order Following Submission of Amended Responses to Master Complaint 4Health News:Gardant Management Solutions Staff Shares Operational Expertise 2
... superstar Tom Cruise, Katie Holmes has silenced rumours that she ... swimsuit. ,Hollywood.com reports that there were rumours ... she looked like she had a round stomach in Madrid. ... a 14-month old daughter Suri. Cruise also has two children ...
... people at the age of three might predict his ... study found. ,Important social skills in early ... recognize social cues from others and engage in positive ... a team of researchers led by Holly Brophy-Herb at ...
... accused US multi-national companies of selling recycled prosthesis in India ... that US companies are selling recycled prosthesis in India," IMA ... US companies are selling knee and hip prosthesis at $4,000 ... $6000. "The secret of cheaper prices in India is that ...
... confirmed Thursday the country's first outbreak of the deadly H5N1 ... the centre of the country. ,"It is ... Administration, Zbynek Semerad, told AFP. Around 1,800 turkeys have already ... of Usti-nad-Orlici, which has a flock of around 6,000 birds. ...
... Medicine in St. Louis are reporting that smoking interferes ... knee ligament injuries, the team discovered cigarette smoking impairs ... delays healing following ligament-repair surgery. They reported their findings ... researchers looked at the mouse medial collateral ligament (MCL), ...
... at MySpace; students star in Facebook; LinkedIn is an ... human counterparts run with the pack at Dogster. ... for canines, referred to as "animal companions" instead of ... ,Among the furry friends featured on the ...
Cached Medicine News:Health News:H5N1 Bird Flu Confirmed at Czech Turkey Farm 2Health News:Cigarette Smoking Delays Ligament Healing 2Health News:Cigarette Smoking Delays Ligament Healing 3Health News:Four-legged Friends Connect Online at Dogster 2Health News:Four-legged Friends Connect Online at Dogster 3
(Date:4/24/2015)... , April 24, 2015  IGI Laboratories, Inc. (NYSE ... based specialty generic pharmaceutical company, announced the Company will ... Tuesday, April 28, 2015 to discuss the 1st quarter ... listen to the call by dialing 1-888-346-3479. International participants ... should ask to be joined into the IGI Laboratories, ...
(Date:4/24/2015)...  Span-America Medical Systems, Inc. (NASDAQ:  SPAN) announced ... second quarter results on Thursday, April 30, after the ... will conduct a conference call at 10:00 a.m. ... financial and operating results for the second quarter ended ... conference call will be available online at ...
(Date:4/24/2015)... -- Introduction of new "Elements" ... for radiosurgery/SBRT   The "Elements" strategy ... the workflow for difficult to treat indications in ... comes full circle with the introduction of automated ... enable on-the-fly generation of consistent treatment plans for ...
Breaking Medicine Technology:Brainlab Introduces New Generation of VMAT* for Brain and Spine at 3rd ESTRO in Barcelona 2
... Pharmaceuticals, Inc. (Nasdaq: DUSA) announces that its ... will be issued on Friday, November 5th at 6:30 ... 8:30 a.m. Friday, November 5th - 8:30 a.m. E.D.T.If ... callers use:502-719-4466Password - DUSAA replay of the call will ...
... BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial -- CARMIEL, Israel, Nov. 2, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... var shortURL = ""; BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed ...
Cached Medicine Technology:Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 2Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 3Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 4Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 5Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 6Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 7Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 8Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 9Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 10
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: