Navigation Links
Protein from pregnancy hormone may prevent breast cancer
Date:11/24/2009

PHILADELPHIA Researchers have found that hormones produced during pregnancy induce a protein that directly inhibits the growth of breast cancer. This protein, alpha-fetoprotein (AFP), may serve as a viable, well-tolerated agent for the treatment and prevention of breast cancer, according to findings published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

"Hormones in pregnancy, such as estrogen, all induce AFP, which directly inhibits the growth of breast cancer," said lead researcher Herbert Jacobson, Ph.D., who is a basic breast cancer researcher in the Center for Immunology and Microbial Diseases and in the Department of Obstetrics, Gynecology and Reproductive Sciences at Albany Medical College, N.Y.

"The body has a natural defense system against breast cancer," he added. "AFP needs to be safely harnessed and developed into a drug that can be used to protect women from breast cancer."

Recent studies have shown that hormones released during pregnancy, such as estrogen, progesterone and human chorionic gonadotropin, reduce a women's risk for breast cancer. AFP is a protein normally produced by the liver and yolk sac of a fetus. Jacobson and colleagues sought to determine whether administering pregnancy hormones to carcinogen-exposed rats led them to produce AFP, which in turn produces the protective effect of pregnancy in the absence of pregnancy.

Results from this study showed that treatment with estrogen plus progesterone, estrogen alone or human chorionic gonadotropin reduced the incidence of mammary cancers in rats. Furthermore, the researchers noted that each of these treatments elevated the serum level of AFP and that AFP directly inhibited the growth of breast cancer cells growing in culture, suggesting that these hormones of pregnancy are preventing breast cancer through their induction of AFP.

Cancer Prevention Research Editorial Board Member Pow
'/>"/>

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

0

GOOD

Page: 1 2

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Penn study finds pro-death proteins required to regulate healthy immune function
3. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
4. Emory researchers identify signaling protein for multiple myeloma
5. Human C-reactive protein regulates myeloma tumor cell growth and survival
6. Lowering Blood Protein Wont Help Kidney Patients
7. Blood protein detects lung cancer, even at earliest stage
8. Natural Protein Could Help Spot, Treat Liver Cancer
9. Heat shock proteins are co-opted for cancer
10. How adhesive protein causes malaria
11. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein from pregnancy hormone may prevent breast cancer
(Date:5/19/2013)... May 19, 2013 These molecular ... US, UK, Spain, Japan, Italy, Germany and France:, ... molecular diagnostics laboratory practice, as well as key ... significant market impact during the next five years. ... and biochip technologies, test formats, detection methodologies, trends ...
(Date:5/19/2013)... 19, 2013 Americans live closer to ... newest American Veterinary Medical Association (AVMA) U.S. Pet Ownership ... owners consider their dog a member of the family, ... as much five years earlier. , According to the ... the national income dedicated to pets has increased every ...
(Date:5/19/2013)... Vegas, Nevada (PRWEB) May 19, 2013 ... agency , is proud to announce the launch it's ... Awards at the MGM Grand on 5/19/2013. Consumers traveling ... all new special pricing available on VegasHotelEscapes.com's website. Travelers ... that they beat any competitors price. , Vegas Hotel ...
(Date:5/19/2013)... Passages Malibu, the leading non-12 step, holistic, and ... the launch of a “Sobriety, Health, and Wellness” survey ... “We are always looking for new ways to engage ... regarding sobriety, what’s working for people, and what isn’t,” ... Passages Addiction Treatment Centers located in Malibu and ...
(Date:5/19/2013)... 19, 2013 HealthEconomics.Com , the ... pleased to unveil a new and exciting service: HE-Xpo: ... a powerful array of real-time communication tools to expand ... and abroad. , HE-Xpo is powered by OnStream ... look and feel of being at a physical trade ...
Breaking Medicine News(10 mins):Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 2Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 3Health News:Molecular Diagnostics Market - US, UK, Spain, Japan, Italy, Germany & France Analysis in New Research Report at ReportsnReports.com 4Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 3Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 2Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 3Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 2Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 3
... team at Brunel University to help people ridden on wheelchair to ... a day. // ,Presently patients are asked to ... program may soon change all that. It requires only a standard ... ,This would enable doctors to build up information on ...
... The Phase II Clinical Trial conducted by a cancer institute ... for kidney cancer with the help of bevacizumab and erlotinib[1], ... effective and may help in prolonging patient's survival. ... treat, especially once it has started to spread to other ...
... a drug containing parts of diptheria toxin as a way ... //cell of patients suffering from advanced melanoma (Skin Cancer) ... trial to test the drug denileukin diftitox (also known as ... seven patients with stage IV disease experienced significant regression or ...
... Mahathir Mohamad suffered a heart attack Thursday and was admitted ... ,Mahathir, 81, had complained of mild chest pains ... Care Unit (CCU) of the National Heart Institute, the hospital ... agency. ,Mahathir had coronary artery bypass surgery in ...
... software used by doctors, AMA President, Dr Mukesh Haikerwal, ... software packages is expanding rapidly in Australia but the ... of standardised testing of clinical software may create potential ... is calling for a national regulatory framework to standardise ...
... novel method of measuring the risk of heart disease, ... their level of affluence, which also contributes to heart ... often eliminated while studying the risk factors and now ... the inclusion of new parameters, to decide the patients ...
Cached Medicine News:Health News:Pain Tracked By 3D Computer Map 2Health News:Systemic Pre-Surgical Treatment Can Prolong Survival Of Kidney Cancer Patients 2Health News:Systemic Pre-Surgical Treatment Can Prolong Survival Of Kidney Cancer Patients 3Health News:Diptheria Toxin And Interleukin2 Help Killing Melanoma Tumour Cells 2
(Date:5/19/2013)... , May 19, 2013  The non-surgical ... temperature radiofrequency (RF) energy is effective in control ... reduces the need for medication 10 years post-procedure, ... today at the Digestive Disease Week (DDW) meeting ... . "The sustained improvement ...
(Date:5/18/2013)... 2013 Although colonoscopy exams prevent many colon ... sensitive method for detecting colorectal cancers 2 , the ... 3 . EndoChoice ® Inc. today unveiled research ... the accuracy of this procedure and greatly reduces the ... discussing these clinical trial results and featuring the Fuse ...
(Date:5/18/2013)... , May 18, 2013 The Open ... , Occupy Psychiatry , and leading ... care, announces a social media campaign showcasing video ... psychiatric model, which focuses on pathology and illness ... with the American Psychiatric Association,s (APA) rollout of ...
Breaking Medicine Technology:Stretta Procedure for GERD: Successful 10 Year Follow-Up Data Presented at Digestive Disease Week--Sustained Improvement, Long-Term Efficacy 2Stretta Procedure for GERD: Successful 10 Year Follow-Up Data Presented at Digestive Disease Week--Sustained Improvement, Long-Term Efficacy 3New Study Shows Full Spectrum Endoscopy Procedure Reduces The 'Miss Rate' of Adenomas During Colonoscopy 2New Study Shows Full Spectrum Endoscopy Procedure Reduces The 'Miss Rate' of Adenomas During Colonoscopy 3New Social Media Campaign Features Stories Of Individuals Who Rejected Psychiatric Diagnoses 2New Social Media Campaign Features Stories Of Individuals Who Rejected Psychiatric Diagnoses 3
Phaco Chopper, double ended; a combination of a modified MicroFinger and a pointed "quick chop" tip, in titanium...
5mm from bend to tip 0.3x2.0mm Tip, Oblong 2 Sided Straight, at 45 degrees; In Titanium...
Angled 40 Degrees, 0.6x0.8 Elliptical Tip; in Titanium...
Double ended with 0.5mm x 10mm and 1.0mm x 15mm blades; both blades gently curved; round serrated handle, In Titanium....
Medicine Products: