Navigation Links
Protein-based coating could help rehabilitate long-term brain function
Date:7/31/2012

Brain-computer interfaces are at the cutting edge for treatment of neurological and psychological disorder, including Parkinson's, epilepsy, and depression. Among the most promising advance is deep brain stimulation (DBS) a method in which a silicon chip implanted under the skin ejects high frequency currents that are transferred to the brain through implanted electrodes that transmit and receive the signals. These technologies require a seamless interaction between the brain and the hardware.

But there's a catch. Identified as foreign bodies by the immune system, the brain attacks the electrodes and forms a barrier to the brain tissue, making it impossible for the electrodes to communicate with brain activity. So while the initial implantation can diminish symptoms, after a few short years or even months, the efficacy of this therapy begins to wane.

Now Aryeh Taub of Tel Aviv University's School of Psychological Sciences, along with Prof. Matti Mintz, Roni Hogri and Ari Magal of TAU's School of Psychological Sciences and Prof. Yosi Shacham-Diamand of TAU's School of Electrical Engineering, has developed a bioactive coating which not only "camouflages" the electrodes in the brain tissue, but actively suppresses the brain's immune response. By using a protein called an "interleukin (IL)-1 receptor antagonist" to coat the electrodes, the multi-disciplinary team of researchers has found a potential resolution to turn a method for short-term relief into a long-term solution. This development was reported in the Journal of Biomedical Materials Research.

Limiting the immune response

To overcome the creation of the barrier between the tissue and the electrode, the researchers sought to develop a method for placing the electrode in the brain tissue while hiding the electrode from the brain's immune defenses. Previous research groups have coated the electrodes with various proteins, says Taub, but the TAU team decided
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Killer stainless steel: New process gives icon of cleanliness antibacterial coating
2. Red wine, fruit compound could help block fat cell formation
3. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
4. Report says new evidence could tip the balance in aspirin cancer prevention care
5. Climate Change Could Be Tough on Seniors Health: Study
6. Could Menthol Cigarettes Pose Even Higher Stroke Risk?
7. Online Tool Could Diagnose Autism Quickly, Developers Say
8. Codeine After Surgery Could Endanger Certain Kids: Study
9. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
10. Discovery could help to develop drugs for organ transplant and cancer patients
11. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2015)... ... August 29, 2015 , ... ... localized area with stretching, soft tissue manipulation. Platelet rich plasma injections also have ... through research to improve treatment outcomes. This localized treatment seems to address ...
(Date:8/28/2015)... Madre, CA (PRWEB) , ... August 28, 2015 ... ... solutions to wound center management, Decatur County Memorial Hospital recently transitioned management companies ... model of Wound Center Management for their outpatient wound center. , Transitioning ...
(Date:8/28/2015)... CA (PRWEB) , ... August 28, 2015 , ... An ... journey that local pizza maker Paul LaRocco has gone through to open a pizzeria ... approval and permitting process tends to take several months, but the current process, having ...
(Date:8/28/2015)... ... ... As reported by Medical Daily on August 22 , Cellfina, a non-invasive ... two years, the longest of any cellulite reduction system currently on the market. ... solution for their cellulite, according to Dr. Robert Weiss, director of the premier MD ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... 20 grams of high grade protein with zero fat, carbs, sugar, gluten, lactose ... been named a finalist for the 2015 SupplySide CPG Editor’s Choice Awards. , ...
Breaking Medicine News(10 mins):Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 2Health News:NEW APPROACH for Treatment of Recurrent Hamstring Strains and Hamstring Tendinosis is Available for the First Time in NYC 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 2Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 3Health News:Decatur County Memorial Hospital Transitions Wound Center Management To Wound Care Advantage and the Luvo Operating System 4Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3
... SALT LAKE CITY, April 17 Dynatronics,Corporation (Nasdaq: ... two new,products: the DynaPro Spinal Health System for ... oscillation therapy unit., "The new DynaPro Spinal ... benefits of decompression with light therapy,core-stabilization exercises and ...
... Blue Shield of,Minnesota (Blue Cross) today released its financial ... of 0.3 percent ($25.1 million) on,full-year revenues of $8.4 ... offset $104 million in operating losses. Blue,Cross remains financially ... claims and operating expenses., More than 90 cents ...
... Heavy drinkers and heavy,smokers develop Alzheimer,s disease years ... or smoke heavily, according to research that,will be ... Anniversary,Annual Meeting in Chicago, April 12-19, 2008., ... if we can,reduce or eliminate heavy smoking and ...
... Susser, MD, DrPH, Anna Cheskis Gelman and Murray Charles ... at the Mailman School of Public Health and professor ... the 2008 Distinguished Investigator Award from NARSAD, the world,s ... Dr. Susser was selected for a study on famine ...
... The National,Association of Specialty Health Organizations (NASHO) ... Award. The recipient of the award,will be ... programs and practices., (Logo: http://www.newscom.com/cgi-bin/prnh/20070227/CLTU004LOGO ... the specialty health industry, we felt it ...
... April 17 Seven children,from across the United ... nerve rerouting surgery for patients,with spina bifida. The ... Royal Oak, Mich., The children previously required ... or endured significant incontinence. But as a result ...
Cached Medicine News:Health News:Dynatronics Introduces New DynaPro Spinal Health System and X5 'Turbo' 2Health News:Blue Cross and Blue Shield of Minnesota Releases 2007 Financial Results 2Health News:Alzheimer's Starts Earlier for Heavy Drinkers, Smokers 2Health News:Ezra Susser, MD, DrPH, receives Distinguished Investigator Award from NARSAD 2Health News:The National Association of Specialty Health Organizations to Recognize Excellence in Technology Education With Industry Award 2Health News:Beaumont Sees Results in Nation's 1st Urinary Nerve Rewiring Surgeries for Spina Bifida Patients 2Health News:Beaumont Sees Results in Nation's 1st Urinary Nerve Rewiring Surgeries for Spina Bifida Patients 3
(Date:8/28/2015)... JACKSONVILLE, Fla. , Aug. 28, 2015  With ... reaching deadlier heights, Jacksonville ... Philip Hemphill is helping to explain why ... Fentanyl is approximately 40 to 50 times more potent ... by recreational users as heroin, the risk of death ...
(Date:8/28/2015)... , Aug. 28, 2015  CytomX Therapeutics, Inc., a ... cancer, today announced the filing of a registration statement ... Commission (SEC) relating to a proposed initial public offering ... be offered and the price range for the offering ... its common stock under the symbol "CTMX" on the ...
(Date:8/28/2015)... 28, 2015 Research ... addition of the "Investigation Report on China,s ... Originally discovered by Welfide (Mitsubishi Tanabe ... Ltd) as an inflammatory drug, pranoprofen was later ... Ltd under the trade name of pranopulin for ...
Breaking Medicine Technology:Lakeview Health's Dr. Philip Hemphill Explains Why Heroin Addicts Are Now Dying of Fentanyl Overdoses 2CytomX Files Registration Statement for Proposed Initial Public Offering 2Investigation Report on China's Pranoprofen Market, 2010-2019 2
... Calif., Feb. 28, 2011 Varian Medical Systems, Inc. (NYSE: ... into a new agreement with Bank of America N.A. to ... share repurchase program.   Under the accelerated repurchase ... N.A. and receive approximately 3.5 million shares, or 85% of ...
... 2011 S*BIO Pte Ltd today announced that its ... (PK/PD) properties leading to significant anti-tumor efficacy in rapamycin-sensitive ... in vitro data on SB2343 were presented ... on Targeting PI3K/mTOR Signaling in Cancer held in San ...
Cached Medicine Technology:Varian Medical Systems Announces New $280 Million Accelerated Stock Repurchase 2Varian Medical Systems Announces New $280 Million Accelerated Stock Repurchase 3S*BIO's Novel Dual mTOR/PI3 Kinase Inhibitor SB2343 Demonstrates Excellent PK/PD Properties Leading to Significant Anti-Tumor Efficacy in Xenograft Models 2S*BIO's Novel Dual mTOR/PI3 Kinase Inhibitor SB2343 Demonstrates Excellent PK/PD Properties Leading to Significant Anti-Tumor Efficacy in Xenograft Models 3
... x 7.5 x 80 mm. Storz ... line designed by Harvey A. Lincoff, ... closed cell sponge which is non-toxic ... rounded edges to minimize scleral intrusion. ...
... 7.5 x 80 mm. Storz offers ... designed by Harvey A. Lincoff, M.D. ... cell sponge which is non-toxic and ... edges to minimize scleral intrusion. These ...
Thin silicone pad implant. Indications: For closing scleral ruptures. Overall length: 7.8 mm....
... Size: 5.0 x 2.5 x 80 mm. Half ... by Harvey A. Lincoff, M.D. has been modified ... design. The material is a closed cell sponge ... with rounded edges to minimize scleral intrusion. These ...
Medicine Products: