Navigation Links
Protein Temporarily Reversed Type 2 Diabetes in Mice

WEDNESDAY, July 16, 2014 (HealthDay News) -- A single injection of a certain protein temporarily reversed symptoms of diabetes in mice, researchers report.

The mice had diet-induced diabetes, which is the equivalent of type 2 diabetes in people. The injection of the protein FGF1 restored their blood sugar levels to a healthy range for more than two days. It also reversed insulin insensitivity, which is the underlying cause of diabetes.

The injection did not cause the kinds of side effects commonly seen with many diabetes medications, according to the Salk Institute scientists, who report their findings in the July 16 issue of Nature.

The findings could help in efforts to develop safer, more effective diabetes drugs for people, the researchers said.

"Controlling glucose [blood sugar] is a dominant problem in our society," study co-corresponding author Ronald Evans, director of Salk's Gene Expression Laboratory in La Jolla, Calif., said in an institute news release. "And FGF1 offers a new method to control glucose in a powerful and unexpected way."

"Many previous studies that injected FGF1 showed no effect on healthy mice," co-corresponding author Michael Downes, a Salk senior staff scientist, said in the news release. "However, when we injected it into a diabetic mouse, we saw a dramatic improvement in glucose."

Much more research is needed before it may be possible to use the protein to develop a drug to treat people with diabetes, the study authors noted. And animal research often does not pan out in human trials.

Nearly 30 million Americans have type 2 diabetes.

More information

The U.S. National Library of Medicine has more about type 2 diabetes.

SOURCE: Salk Institute, news release, July 16, 2014


Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ORNL, UTGSM study compares structures of Huntingtons disease protein
2. Healthy Vitamins Releases New Recipes for Garden of Life's Protein Powders
3. Neurons, brain cancer cells require the same little-known protein for long-term survival
4. EnergyFirst Acquires Permalean - Manufacturer of All Natural Protein Bars and Powders
5. Protein pushes breast cancer cells to metastasize
6. NUS researchers discover novel protein complex with potential to combat gastric cancer
7. Mechanism discovered for attaching an on switch that helps cells accessorize proteins
8. Proteins causing daytime sleepiness tied to bone formation, target for osteoporosis
9. Viral infections, including flu, could be inhibited by naturally occurring protein
10. Fungal protein found to cross blood-brain barrier
11. Mount Sinai researchers identify protein that keeps blood stem cells healthy as they age
Post Your Comments:
Related Image:
Protein Temporarily Reversed Type 2 Diabetes in Mice
(Date:6/27/2016)... CA (PRWEB) , ... June 27, 2016 , ... ... College District , the only authorized OSHA Training Institute Education Center headquartered in ... by protecting their workers from extreme heat at their worksites. Employers with ...
(Date:6/27/2016)... California (PRWEB) , ... June 27, 2016 , ... "FCPX ... fully customizable inside of Final Cut Pro X," said Christina Austin - CEO of ... unique style. Final Cut Pro X users can now reveal the media ...
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... today its affiliation with Tennessee Counseling Association. This new relationship allows ... the Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... payment industry today announced its strategic partnership with Connance, a healthcare industry ... The two companies’ proven, proprietary technology combine to provide health systems, hospitals ...
(Date:6/27/2016)... , ... June 27, 2016 , ... ... edge technology to revolutionize the emergency ambulance transport experience for the millions of ... of how Uber has disrupted the taxi industry through the use of technology. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
(Date:6/23/2016)... and INDIANAPOLIS , June 23, 2016 ... Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, the ... announced today online at by the ... diabetes stand in the way of academic and community ... Foundation,s scholarship program since 2012, and continues to advocate ...
(Date:6/23/2016)... PRINCETON, N.J. , June 23, 2016  Guerbet ... of Premier Inc.,s Supplier Horizon Award . ... this year, Guerbet was recognized for its support of ... value creation through clinical excellence, and commitment to lower ... delighted to receive this recognition of our outstanding customer ...
Breaking Medicine Technology: