Navigation Links
Protein Nasal Spray Revives Sleep-Deprived Monkeys
Date:1/4/2008

A natural brain compound could help shift workers or those with narcolepsy, scientists say

FRIDAY, Jan. 4 (HealthDay News) -- The naturally occurring brain protein called orexin-A may be key to undoing the negative mental effects of staying up all night, at least in monkeys.

Orexin-A is a peptide (a kind of protein) made in the brain to regulate sleep, according to a team at the Wake Forest University School of Medicine in Winston-Salem, N.C. Normal levels of orexin-A help people to stay awake during the day.

When people do not get enough sleep, the brain attempts to make more of the peptide to preserve alertness but often fails to fight off the body's daily sleep cycle, according to the researchers.

The Wake Forest team studied the effects of orexin-A on monkeys that were deprived of sleep for 30 to 36 hours.

When the monkeys were challenged with tasks they had been trained to do that required some thought, they were not able to perform at their normal levels.

However, monkeys that endured sleep deprivation and were then given orexin-A improved their performance to a normal level. Additionally, brain imaging revealed that the monkeys' brains had the same pattern of activity when they were given the peptide as when they had not lost any sleep.

Orexin-A can be given either by IV-drip or nasal spray, although the monkeys performed better with the nasal spray, reported the researchers.

The researchers suggested that these results could have important implications for people suffering from the sleep disorder narcolepsy and for people whose lifestyles may cause sleep deprivation, such as shift workers.

The results were published in the Dec. 31 edition of The Journal of Neuroscience.

More information

To learn more about how to improve sleep habits, visit the American Academy of Family Physicians.



-- Madeline Vann



SOURCE: Wake Forest University Baptist Medical Center, news release, Dec. 31, 2007


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Protein a possible key to allergy and asthma control
2. Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
3. Receptor protein appears to be key in breakdown of kidney filtration
4. Protein-dependent switch regulates intracellular trafficking in epithelial cells
5. Researchers led by Penn vet uncover the delicate protein balance behind the immune system response
6. Extracellular protein sensitizes ovarian cancer cells to chemotherapy
7. St. Jude Finds Mechanism for Faulty Protein Disposal
8. St. Jude finds mechanism for faulty protein disposal
9. Brain Protein May Be a Clue to Autism
10. Protein found that may provide relief from neuropathic pain
11. Activating protein enhances average lifespan, limits age-related disease in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/1/2017)... ... 01, 2017 , ... Expert on international living and leading a healthy lifestyle, ... , Time & Go app is the ultimate strategic compass that helps users to ... methods enable people to work smarter, not harder, that's why Time & Go app ...
(Date:3/1/2017)... ... 01, 2017 , ... March 2017 – All year round the treadmill represents ... stop training to brave the cold weather, snow or ice. Treadmill running poses special ... help protect these vulnerable joints, says orthopaedic surgeon Kevin D. Plancher, MD, founder of ...
(Date:3/1/2017)... ... March 01, 2017 , ... “McFarnia”: a suspenseful tale of a father who ... life and mysterious disappearance. “McFarnia” is the creation of published author Tony Pierzchala, a ... currently serves as a Chaplain with Transport for Christ at a truck stop in ...
(Date:3/1/2017)... ... , ... “Letter of Love”: a tale of young love and war. ““Letter ... Civil War in El Salvador, wife, mother, and co-founder of a Christian College. , ... to serve in very poor communities, and I study psychology. I lived the civil ...
(Date:3/1/2017)... ... March 01, 2017 , ... “The Affair is Over Now Go ... emotional upheaval of an extramarital affair. “The Affair is Over Now Go Live Your ... former lay pastor who has dedicated her professional life to teaching and writing about ...
Breaking Medicine News(10 mins):
(Date:3/1/2017)... India and PRINCETON, N.J. ... Industries Ltd (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: ... subsidiaries or associate companies) today announced that several ... clinical trials (reSURFACE 1 and 2) of tildrakizumab, ... treatment of moderate-to-severe plaque psoriasis, will be presented ...
(Date:3/1/2017)... March 1, 2017  The Board of Directors of ... Turfe as the new CEO and Chairman of ... of long-time Chairman and CEO William R. Cobb ... nationwide search, and brings a wealth of experience in ... "In a pool of incredibly qualified ...
(Date:3/1/2017)... March 1, 2017 Lo stesso sistema sara, visibile nello ... Paramed Medical Systems sta installando la settima unità MROpen in ... nel nuovo centro dell,European Scanning Center (ESC) a Cardiff. ESC attualmente gestisce altri ... Manchester. Continue Reading ... ...
Breaking Medicine Technology: