Navigation Links
Protein Nasal Spray Revives Sleep-Deprived Monkeys
Date:1/4/2008

A natural brain compound could help shift workers or those with narcolepsy, scientists say

FRIDAY, Jan. 4 (HealthDay News) -- The naturally occurring brain protein called orexin-A may be key to undoing the negative mental effects of staying up all night, at least in monkeys.

Orexin-A is a peptide (a kind of protein) made in the brain to regulate sleep, according to a team at the Wake Forest University School of Medicine in Winston-Salem, N.C. Normal levels of orexin-A help people to stay awake during the day.

When people do not get enough sleep, the brain attempts to make more of the peptide to preserve alertness but often fails to fight off the body's daily sleep cycle, according to the researchers.

The Wake Forest team studied the effects of orexin-A on monkeys that were deprived of sleep for 30 to 36 hours.

When the monkeys were challenged with tasks they had been trained to do that required some thought, they were not able to perform at their normal levels.

However, monkeys that endured sleep deprivation and were then given orexin-A improved their performance to a normal level. Additionally, brain imaging revealed that the monkeys' brains had the same pattern of activity when they were given the peptide as when they had not lost any sleep.

Orexin-A can be given either by IV-drip or nasal spray, although the monkeys performed better with the nasal spray, reported the researchers.

The researchers suggested that these results could have important implications for people suffering from the sleep disorder narcolepsy and for people whose lifestyles may cause sleep deprivation, such as shift workers.

The results were published in the Dec. 31 edition of The Journal of Neuroscience.

More information

To learn more about how to improve sleep habits, visit the American Academy of Family Physicians.



-- Madeline Vann



SOURCE: Wake Forest University Baptist Medical Center, news release, Dec. 31, 2007


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Protein a possible key to allergy and asthma control
2. Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
3. Receptor protein appears to be key in breakdown of kidney filtration
4. Protein-dependent switch regulates intracellular trafficking in epithelial cells
5. Researchers led by Penn vet uncover the delicate protein balance behind the immune system response
6. Extracellular protein sensitizes ovarian cancer cells to chemotherapy
7. St. Jude Finds Mechanism for Faulty Protein Disposal
8. St. Jude finds mechanism for faulty protein disposal
9. Brain Protein May Be a Clue to Autism
10. Protein found that may provide relief from neuropathic pain
11. Activating protein enhances average lifespan, limits age-related disease in mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... N.J. (PRWEB) , ... October 13, 2017 , ... The ... Holly Day Market. Featuring a collection of specialty vendors and unique items from across ... personalized and quality-focused health and wellness services offered by the VNA. The boutique ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of ... announced today its plans to open a flagship location in Covington, LA at 401 ... Rooms To Go store next to Office Depot in the Holiday Square shopping center. ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... delivery system that we intend to develop to enable prevention of a major ... to severe hearing loss, especially in pediatric patients. For cisplatin, hearing loss is ...
(Date:10/12/2017)... GRAND RAPIDS, Mich. (PRWEB) , ... October 12, ... ... OnSite Wellness, has been named one of Michigan’s 2017 Best and Brightest in ... Best and Brightest in Wellness® awards program on Friday, Oct. 20 from 7:30 ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... , Sept. 22, 2017  As the latest Obamacare ... Bill Cassidy (R-LA) and Lindsey Graham ... that the medical device industry is in an odd ... tax, the 2.3% excise tax on medical device sales ... also want covered patients, increased visits and hospital customers ...
(Date:9/19/2017)... venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound ... ... Jim Bertolina, PhD ... Tom Tefft ... device executive Josh Stopek , PhD, who has led R&D and business development teams ...
(Date:9/18/2017)... KALAMAZOO, Mich. , Sept. 18, 2017  PMD ... OptiMed Specialty Pharmacy of Kalamazoo, Mich. ... strategic hub service that expedites and streamlines patient and ... Spiro PD 2.0, and wellness management services.  ... medical device used to measure lung function for a ...
Breaking Medicine Technology: