Navigation Links
Protein Clumps May Appear Years Before Memory Problems
Date:7/29/2009

Discovery could help in Alzheimer's prevention efforts, researcher says,,

WEDNESDAY, July 29 (HealthDay News) -- Amyloid protein deposits in the brain play a role in disrupting the memory formation process long before a person shows symptoms of the memory impairment of Alzheimer's disease, a new study contends.

Previous research had suggested that clumps of amyloid protein, which damage neurons and are characteristic of Alzheimer's disease, begin appearing many years before Alzheimer's symptoms appear. But the link between the deposits and memory impairment had not been clearly demonstrated in humans.

In the new study, which appears in the July 30 issue of Neuron, U.S. researchers used medical imaging to examine the brains of older people who did not have significant memory impairment.

"Two recent advances in neuroimaging now allow us to explore the early, asymptomatic phase of [Alzheimer's disease], the ability to measure amyloid distribution in living humans and the identification of sensitive markers of brain dysfunction" in the disease, Dr. Reisa Sperling, of the Center for Alzheimer's Research and Treatment at Brigham and Women's Hospital in Boston and lead author of the study, said in a news release from the journal's publisher.

The researchers found that a number of study participants had amyloid deposits and abnormal activity in areas of the brain believed to be involved in memory function.

The results could help in efforts to find ways to predict and treat cognitive decline in people at risk for Alzheimer's, the study authors noted.

"Longitudinal studies are certainly needed, but our findings are consistent with the premise that cognitively intact older individuals with amyloid pathology may already be in the early stages of [Alzheimer's disease]," Sperling said. "The combination of molecular and functional imaging techniques may prove useful in monitoring disease progression prior to significant clinical symptoms, as well as the response to amyloid-modifying therapeutic agents in subjects at risk for developing [Alzheimer's disease]."

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.



-- Robert Preidt



SOURCE: Cell Press, news release, July 29, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Penn study finds pro-death proteins required to regulate healthy immune function
3. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
4. Emory researchers identify signaling protein for multiple myeloma
5. Human C-reactive protein regulates myeloma tumor cell growth and survival
6. Lowering Blood Protein Wont Help Kidney Patients
7. Blood protein detects lung cancer, even at earliest stage
8. Natural Protein Could Help Spot, Treat Liver Cancer
9. Heat shock proteins are co-opted for cancer
10. How adhesive protein causes malaria
11. Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Protein Clumps May Appear Years Before Memory Problems
(Date:12/7/2016)... ... December 07, 2016 , ... Kenall Manufacturing, a leader in sealed healthcare ... The MPCNGX is a multi-function, sealed, LED luminaire that meets the needs of everyone ... when it’s needed. , A 2’ x 4’ model features four modes: ...
(Date:12/7/2016)... ... December 07, 2016 , ... OC87 Recovery Diaries ... schizophrenic mother in a unique, personal perspective through animation. , That woman ... addictive disorders at her private psychotherapy practice. Sheri’s mother, Pearl, lived with schizophrenia. ...
(Date:12/7/2016)... ... 2016 , ... Castle Dermatology Institute is now offering liquid facelifts with ... appearance to the face. Dr. Peyman Ghasri and Dr. Pedram Ghasri, San Fernando ... to rejuvenate and renew the facial appearance. , Sculptra is a highly effective ...
(Date:12/7/2016)... ... 07, 2016 , ... When it came time to blow out his candles on his 14th ... Pediatric Heart Transplant team at Joe DiMaggio Children’s Hospital surprised his family with ... 30th heart transplant recipient. , “He was playing at home, when we got the ...
(Date:12/7/2016)... TX (PRWEB) , ... December 07, 2016 , ... ... offering insurance and financial planning services to families and business owners in the ... funds on behalf of the Dallas Fallen Officer Foundation. , Established in 2009 ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)...  Licenders is bringing their 100% all-natural lice removal service to ... at 203 13 th Street was specifically chosen to make ... "Our goal is to ease parents, stress and bring their ... children right back to class without skipping a beat. The best ... for the whole family," Licenders President Adie Horowitz states. ...
(Date:12/6/2016)... 6, 2016  "Blood Tests replace Surgical Biopsies. ... The Diagnostic, Monitoring and Screening Test opportunities ... is occurring using in vitro blood testing to ... impressive backing, has announced a single blood test ... faster than the market. New technology that definitively ...
(Date:12/6/2016)... 2016 Diabetes & Obesity Drug Development Pipeline ... disease cluster is currently dominated by therapeutics indicated for ... mellitus (T2DM), and the majority of the pipeline, in ... attributable to these indications. While products indicated for obesity ... are a large number of these products in the ...
Breaking Medicine Technology: