Navigation Links
Protein Appears Key to Intestinal Balance
Date:2/19/2010

Researchers say discovery could offer insight into various illnesses

FRIDAY, Feb. 19 (HealthDay News) -- A protein that plays a key role in protecting the intestinal tract from bacterial infection and inflammation has been identified by U.S. researchers.

Reduced levels of the protein -- granulocyte-macrophage colony-stimulating factor (GM-CSF) -- could be an underlying factor in severe illness caused by pathogens such as E. coli and intestinal inflammation in inflammatory bowel diseases such as Crohn's disease, the researchers said.

"The gut normally is in a chronic state of low-grade inflammation that is beneficial," study author Dr. Martin Kagnoff, professor emeritus of medicine and pediatrics at the University of California, San Diego, School of Medicine, said in a university news release.

"This study shows that GM-CSF has a profound influence in the regulation of cells that determine whether the gut lives in peace with this inflammation or becomes severely inflamed during infection," he said. "Any time that delicate balance is disrupted, all heck can break loose."

Kagnoff said the findings might help explain why some people with Crohn's disease benefit from receiving GM-CSF. A greater understanding of the role of GM-CSF in the gut could lead to new treatments based on the protein, he added.

The study is published in Cell Host & Microbe.

More information

The American Academy of Family Physicians has more about inflammatory bowel disease.



-- Robert Preidt



SOURCE: University of California, San Diego Health Sciences, news release, Feb. 17, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Protein Sciences Corporation Announces Profitable and Cash Flow Positive Results for 2009 and Management Realignment
2. Smithfield, United Food and Commercial Workers Union, and Food Networks Paula Deen to Deliver 150,000 Servings of Protein to San Francisco Food Bank
3. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
4. Research highlights role of protein pair in obesity regulation
5. New and Delicious, Almond Butter Filled, Cookie Bites With 35.7% Protein to Help Manage Weight and Build Muscle
6. Scientists ID a protein that splices and dices genes
7. 3 brain diseases linked by toxic form of same neural protein
8. Protein Levels in Urine Help Predict Kidney Function
9. UC Davis researchers identify brain protein for synapse development
10. New Study Reveals Protein Produced by Spleen Reduces Risk of Deadly Lung Infection
11. Tobacco Toxin Helps a Protein Cause Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... Santa Rosa, California (PRWEB) November 26, 2014 ... be making never before seen reductions in prices of ... and Liposomal Vitamin D3 . Discounts ... only. , GI for Life’s proprietary ColoVite ... leading board-certified gastroenterologists to promote colon health. One easy-to-take ...
(Date:11/26/2014)... IL (PRWEB) November 26, 2014 ... communication management solutions, has been award the ... Magazine. , This award comes as a great ... capabilities within the Lync ecosystem. Specifically, ISI offers ... all modes of Lync communication, including voice, video, ...
(Date:11/26/2014)... November 26, 2014 Medical suction and ... out of 5. This score represents steady growth in ... years to 2014 as a result of swelling demand ... machines, which are largely considered nondiscretionary. IBISWorld market research ... buyers have some degree of flexibility, given the low ...
(Date:11/26/2014)... Baton Rouge, Louisiana (PRWEB) November 26, 2014 ... and neck pain relief and specialists in minimally ... Dr. K. Samer Shamieh into the rapidly growing ... management specialists. The addition coincides with the ... cutting-edge, reliable medical treatment for Louisiana residents who ...
(Date:11/26/2014)... One of the most important and vital decisions a ... is choosing the ideal wedding dress and bridesmaid dresses. ... high quality outfits. Today, BellasDress.com has unveiled its new ... their suitable bridesmaid gowns here at discount prices. , ... scintillating and highlight all their most beautiful features while ...
Breaking Medicine News(10 mins):Health News:GI For Life Slashes Prices by 40% on Liposomal Vitamin D3 and ColoVite Colon Health Formula for a Limited Time 2Health News:ISI Telemanagement Solutions, Inc. has been Awarded the 2014 Microsoft Lync Pioneer Award 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 4Health News:Louisiana Back Institute Welcomes Dr. K. Samer Shamieh into Medical Provider Network 2Health News:Royal Blue Bridesmaid Dresses Now Are Available for Christmas at BellasDress.com 2
... Dialysis Corporation of,America (Nasdaq: DCAI ) ... located at the St. Thomas More Nursing and,Rehabilitation Center, ... St.,Thomas More Center, as well as the surrounding community. ... 24 treatment stations and is currently caring for,approximately 145 ...
... Inc., a Boston-based,award-winning medical tourism facilitator, has ... an Indianapolis-based health benefits company to provide,global ... affiliated health plan,in Wisconsin. Healthbase will handle ... WellPoint members. , ...
... and flu,season, which means misery for kids and the parents trying ... asking parents to resist the urge to give children under,the age ... Such drugs can have serious side effects on the smallest ... drowsiness,difficulty breathing and even death. , "Some ...
... 5 Health-conscious consumers who are,tired of taking several ... smaller,more powerful alternative to fish oil supplements in MegaRed(TM) ... fatty acids combined with,powerful antioxidants, and is three times ... softgel per day -- which is about as small ...
... Jan. 5 /PRNewswire-FirstCall/ - Hard to Treat Diseases (HTDS) ... updates where amongst other things the company addressed several ... that it has finalized its bilateral negotiations with Slavica ... Chem is a spin off of Renuyu Biochem, a ...
... Soliris(R) INCLINE VILLAGE, Nev., and CHESHIRE, Conn., Jan. 5 ... Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN ) today ... license agreement and settlement agreement that resolve the legal disputes ... PDL,s patents known as the Queen et al. patents. ...
Cached Medicine News:Health News:Dialysis Corporation of America Announces Acquisition of Maryland Dialysis Center 2Health News:Healthbase Collaborates with WellPoint to Bring Affordable Medical Tourism Solutions 2Health News:Caution Urged When Giving Kids Cold and Flu Meds 2Health News:Three Times More Powerful Than Fish Oil, MegaRed(TM) Omega-3 Krill Oil Now Available Nationwide 2Health News:Three Times More Powerful Than Fish Oil, MegaRed(TM) Omega-3 Krill Oil Now Available Nationwide 3Health News:Hard To Treat Diseases (HTDS) Completes E Europe Merger 2Health News:Alexion Pharmaceuticals and PDL BioPharma Resolve Patent Dispute 2Health News:Alexion Pharmaceuticals and PDL BioPharma Resolve Patent Dispute 3
(Date:11/26/2014)... , Nov. 25, 2014  Medtronic,s roughly ... has been widely discussed in the media for ... creating a stronger leading player in one of ... Information.  The healthcare market research firm said  the ... feature a diverse set of solutions spanning inpatient ...
(Date:11/26/2014)...   Heska Corporation (NASDAQ: HSKA ) ... of advanced veterinary diagnostic and other specialty veterinary products ... will attend The Benchmark Company, LLC,s Micro Cap Discovery Conference ... held at The Palmer House Hilton, 17 E. Monroe Street, ... 2:30 p.m. Please email hska@haydenir.com or contact your ...
(Date:11/26/2014)... 25, 2014  Array BioPharma Inc. (Nasdaq: ... its Chief Executive Officer, Ron Squarer ... conferences.  The public is welcome to participate ... Array BioPharma website:  www.arraybiopharma.com .Event: Piper Jaffray ...  Eastern Time Location: Palace Hotel, New York ...
Breaking Medicine Technology:Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 2Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 3Heska to Attend Benchmark Micro Cap Discovery Conference 2
... Pharmaceuticals, Inc., a Scottsdale, Arizona-based, emerging pharmaceutical company, ... of the assets of Scarista Limited. In particular, Prismic ... Limited, a wholly owned subsidiary of Amarin Corporation, ... a portfolio of issued U.S. and foreign composition ...
... ReportsnReports adds new market research report , Branded Prescription ... research says in 2011, the Branded PharmaVitae Universe achieved sales ... of 9.3% between 2003 and 2010, and a net sales ... grow by a CAGR of only 1.0%, with no growth ...
Cached Medicine Technology:Prismic Pharmaceuticals Acquires Scarista's Exclusive License to Amarin's Omega-3 Patents for CNS Disorders 2Branded Prescription Pharmaceutical Sales Outlook to 2016 - Sales to Rise by Just $29bn by 2016 2Branded Prescription Pharmaceutical Sales Outlook to 2016 - Sales to Rise by Just $29bn by 2016 3
Camera and light source in one compact "Plug-and-Play" device....
... are based on a completely new and revolutionary ... allows a tremendous image size without distortion. The ... the joint with less rotation of the telescope. ... tight and secure camera connection is introduced. It ...
... ProSpec, the system of choice for customers ... in medium throughput laboratories in more than ... milestone. Dade Behring is pleased to announce ... system., ,The customer centered development process ...
... Wavefront analysis with the WASCA Analyzer ... diagnosis. Unlike existing diagnostic techniques, the WASCA ... eye from thecornea to the retina. ... Analyzer also supplies higher order aberrations which ...
Medicine Products: