Navigation Links
Protein Appears Key to Intestinal Balance
Date:2/19/2010

Researchers say discovery could offer insight into various illnesses

FRIDAY, Feb. 19 (HealthDay News) -- A protein that plays a key role in protecting the intestinal tract from bacterial infection and inflammation has been identified by U.S. researchers.

Reduced levels of the protein -- granulocyte-macrophage colony-stimulating factor (GM-CSF) -- could be an underlying factor in severe illness caused by pathogens such as E. coli and intestinal inflammation in inflammatory bowel diseases such as Crohn's disease, the researchers said.

"The gut normally is in a chronic state of low-grade inflammation that is beneficial," study author Dr. Martin Kagnoff, professor emeritus of medicine and pediatrics at the University of California, San Diego, School of Medicine, said in a university news release.

"This study shows that GM-CSF has a profound influence in the regulation of cells that determine whether the gut lives in peace with this inflammation or becomes severely inflamed during infection," he said. "Any time that delicate balance is disrupted, all heck can break loose."

Kagnoff said the findings might help explain why some people with Crohn's disease benefit from receiving GM-CSF. A greater understanding of the role of GM-CSF in the gut could lead to new treatments based on the protein, he added.

The study is published in Cell Host & Microbe.

More information

The American Academy of Family Physicians has more about inflammatory bowel disease.



-- Robert Preidt



SOURCE: University of California, San Diego Health Sciences, news release, Feb. 17, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Protein Sciences Corporation Announces Profitable and Cash Flow Positive Results for 2009 and Management Realignment
2. Smithfield, United Food and Commercial Workers Union, and Food Networks Paula Deen to Deliver 150,000 Servings of Protein to San Francisco Food Bank
3. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
4. Research highlights role of protein pair in obesity regulation
5. New and Delicious, Almond Butter Filled, Cookie Bites With 35.7% Protein to Help Manage Weight and Build Muscle
6. Scientists ID a protein that splices and dices genes
7. 3 brain diseases linked by toxic form of same neural protein
8. Protein Levels in Urine Help Predict Kidney Function
9. UC Davis researchers identify brain protein for synapse development
10. New Study Reveals Protein Produced by Spleen Reduces Risk of Deadly Lung Infection
11. Tobacco Toxin Helps a Protein Cause Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/7/2020)... ... January 06, 2020 , ... ... impairment, has announced the Best Memory Care Facilities in Lakeland, Florida. The guide ... and amenities. , According to the Alzheimer’s Association , 5.6 million ...
(Date:1/7/2020)... ... January 07, 2020 , ... R3 Stem Cell is ... presentations and procedures for hair restoration, facial rejuvenation and sexual wellness. The full ... aesthetics has become incredibly popular over the past few years as practitioners are ...
(Date:1/7/2020)... ... 07, 2020 , ... MMJ International Holdings, the premier medical cannabis research company, ... its THC and CBD proprietary drug formulation which will be used for the treatment ... company is confident that it will bring much needed relief to patients suffering from ...
(Date:1/5/2020)... ... January 04, 2020 , ... Urban Air, the premier family-friendly indoor ... The company known for endless hours of trampolining, rock climbing, dodge-balling and more, has ... Ballenger Creek, Frederick, MD. , “We know families are looking for ways to spend ...
(Date:1/3/2020)... ... January 03, 2020 , ... Hot off the presses! ezW2 2019 tax preparation software from ... ezW2 2019 and later versions will support eFile W2/W3 for the following states: ... MO, MS, MT, NC, ND, NE, NY, OK, OR, PA, SC, UT, VA, VT, WI ...
Breaking Medicine News(10 mins):
(Date:1/8/2020)... ... January 09, 2020 , ... R3 Stem Cell is ... over 50 first rate presentations and procedure videos. The course is incredibly useful and ... carrier. , For years, R3 Stem Cell has been the leader for regenerative training ...
(Date:1/7/2020)... ... January 06, 2020 , ... ... impairment, has announced the Best Memory Care Facilities in Fargo, North Dakota. The ... features and amenities. , According to the Alzheimer’s Association , 5.6 ...
(Date:1/3/2020)... BEVERLY HILLS, Calif. (PRWEB) , ... January 02, 2020 , ... ... Hills, Dr. Matt Nejad , leading expert and educator in cosmetic and biomimetic ... Nejad Institute with a new website at http://www.nejadinstitute.com . , Dentists from ...
Breaking Medicine Technology: