Navigation Links
Protection for stressed-out bacteria identified
Date:10/8/2008

An international team of researchers is a step closer to understanding the spread of deadly diseases such as listeriosis, after observing for the first time how bacteria respond to stress.

The research, published in the October issue of the prestigious international journal Science, details how a huge molecule called a stressosome protects bacterial cells from external stress and danger.

Scientists from the University of Newcastle in Australia, and Newcastle University and Imperial College in the United Kingdom, collaborated on the discovery.

Associate Professor Peter Lewis from the Faculty of Science and Information Technology at the University of Newcastle in Australia said until now, researchers had not fully understood how bacteria responded to stress and potential danger.

"It is important to understand the changes that occur when bacteria are under stress as this is the point at which they are likely to become most infectious.

"The protein molecules that make up the stressosome are found in a very wide range of bacteria. Some of these bacteria cause diseases such as listeriosis that has a 30 per cent mortality rate, and melioidosis that has a mortality rate as high as 90 per cent and is a significant health problem in northern Australia and south-east Asia.

"With bacteria becoming increasingly resistant to antibiotics, understanding how the stress response is controlled could lead to the development of drugs that help prevent bacterial infection from occurring."

Lead author of the Science paper, Professor Rick Lewis from Newcastle University in the United Kingdom, said the team used groundbreaking techniques to observe the stressosomes. Electron microscopy techniques were developed by Professor Marin van Heel of Imperial College and Associate Professor Peter Lewis developed the fluorescence microscopy imaging techniques.

"We knew that when bacteria were stressed, a warning signal would be sent from the surface to the inside of the cell. The stressosome would then respond by triggering new proteins in the cell to react to the stress.

"Our latest work has revealed the structure and number of stressosomes per cell. This has helped us understand how quickly the stressosomes respond to external stresses and prepare the cell to adapt to changes in its environment and ensure its survival."


'/>"/>

Contact: Blythe Hamilton
Blythe.Hamilton@newcastle.edu.au
61-249-216-856
Research Australia
Source:Eurekalert

Related medicine news :

1. Survey reveals disparities in skin cancer knowledge, protection among high school students
2. Scientists Develop Natural Protection for Stored Foods
3. Despite overeating, morbidly obese mice gain protection against diabetes
4. DuPont Focused on Meeting Global Demands for Greater Safety & Protection
5. Residual fetal cells in women may provide protection against breast cancer
6. Hospital Coalition Says Governors No-Fault Bill Signing Provides a Great Protection for Florida Consumers
7. Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients
8. Long Term Care Newsletter Debuts, Published by LTC Financial Partners; Advice on Living Better, Not Just Longer, With Financial Protection
9. Abbotts Environmental Protection Initiatives Again Recognized by the State of Illinois
10. Safe Sex Passport Launches to Provide Breakthrough Protection Against STDs and HIV
11. URAC Names Medco as a Finalist in First-ever Best Practices in Consumer Empowerment and Protection Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... this installment is bolstered by inspiring human interest stories, courtesy of leaders in ... trends and tech within the industry, from leading advocates and associations—namely Jones & ...
(Date:5/26/2016)... ... May 26, 2016 , ... There are many ways to ... Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the grill. Of ... grilling is their favorite way to cook a hot dog, far outpacing other cooking ...
(Date:5/26/2016)... , ... May 26, 2016 , ... Connor Sports, ... basketball as a partner for the Tamika Catchings Legacy Tour that will ... industry leader in hardwood basketball surfaces in all forms and levels of the game, ...
(Date:5/26/2016)... ... ... MadgeTech will be showcasing its line of data logging products , ... MadgeTech headquarters. With products sold in more than 100 countries around the world, MadgeTech ... , In 2012, NASA strategically set up 17 RHTemp101A MadgeTech data loggers around ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... Memorial Day ... why Amica Insurance is sharing tips to make sure your family and ... from the National Safety Council, there may be 439 deaths and an additional 50,500 ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... the necessity of health literacy within the technology advancement of diagnostic imaging. According to a ... majority of oncology patients undergo imaging screenings without understanding the nuanced risks associated with ... ... ... Diagnostic Imaging Ampronix ...
(Date:5/27/2016)... Israel , May 27, 2016 ... of the Dario™ Diabetes Management Tool, today announced that the ... at the Marcum MicroCap Conference being held June 1-2 in ... Micro Invitational, being held June 7-9 in Los ... Ben-David will discuss recent corporate and operational milestones, including the ...
(Date:5/27/2016)... According to the 2016 report, ... ambulatory blood pressure monitoring system market growth. With aging, ... to respond to different pressure rates, leading to hypertension ... various cardiovascular disorders such as heart failure, stroke, coronary ... growing in prevalence each year. WHO estimates that 17 ...
Breaking Medicine Technology: