Navigation Links
Protection for stressed-out bacteria identified
Date:10/8/2008

An international team of researchers is a step closer to understanding the spread of deadly diseases such as listeriosis, after observing for the first time how bacteria respond to stress.

The research, published in the October issue of the prestigious international journal Science, details how a huge molecule called a stressosome protects bacterial cells from external stress and danger.

Scientists from the University of Newcastle in Australia, and Newcastle University and Imperial College in the United Kingdom, collaborated on the discovery.

Associate Professor Peter Lewis from the Faculty of Science and Information Technology at the University of Newcastle in Australia said until now, researchers had not fully understood how bacteria responded to stress and potential danger.

"It is important to understand the changes that occur when bacteria are under stress as this is the point at which they are likely to become most infectious.

"The protein molecules that make up the stressosome are found in a very wide range of bacteria. Some of these bacteria cause diseases such as listeriosis that has a 30 per cent mortality rate, and melioidosis that has a mortality rate as high as 90 per cent and is a significant health problem in northern Australia and south-east Asia.

"With bacteria becoming increasingly resistant to antibiotics, understanding how the stress response is controlled could lead to the development of drugs that help prevent bacterial infection from occurring."

Lead author of the Science paper, Professor Rick Lewis from Newcastle University in the United Kingdom, said the team used groundbreaking techniques to observe the stressosomes. Electron microscopy techniques were developed by Professor Marin van Heel of Imperial College and Associate Professor Peter Lewis developed the fluorescence microscopy imaging techniques.

"We knew that when bacteria were stressed, a warning signal would be sent from the surface to the inside of the cell. The stressosome would then respond by triggering new proteins in the cell to react to the stress.

"Our latest work has revealed the structure and number of stressosomes per cell. This has helped us understand how quickly the stressosomes respond to external stresses and prepare the cell to adapt to changes in its environment and ensure its survival."


'/>"/>

Contact: Blythe Hamilton
Blythe.Hamilton@newcastle.edu.au
61-249-216-856
Research Australia
Source:Eurekalert

Related medicine news :

1. Survey reveals disparities in skin cancer knowledge, protection among high school students
2. Scientists Develop Natural Protection for Stored Foods
3. Despite overeating, morbidly obese mice gain protection against diabetes
4. DuPont Focused on Meeting Global Demands for Greater Safety & Protection
5. Residual fetal cells in women may provide protection against breast cancer
6. Hospital Coalition Says Governors No-Fault Bill Signing Provides a Great Protection for Florida Consumers
7. Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients
8. Long Term Care Newsletter Debuts, Published by LTC Financial Partners; Advice on Living Better, Not Just Longer, With Financial Protection
9. Abbotts Environmental Protection Initiatives Again Recognized by the State of Illinois
10. Safe Sex Passport Launches to Provide Breakthrough Protection Against STDs and HIV
11. URAC Names Medco as a Finalist in First-ever Best Practices in Consumer Empowerment and Protection Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... ... healthcare compliance program management, will showcase a range of technology and learning solutions ... Living (NCAL) Convention and Expo to be held October 14–18, 2017 at the ...
(Date:10/12/2017)... ... October 12, 2017 , ... The ... demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, ... to meet the highest standard. , These products are also: Gluten Free, ...
(Date:10/12/2017)... ... ... Asante, a nationally recognized health system in southern Oregon, ... health joint venture through an agreement, effective October 1, 2017, to create AccentCare ... company with Asante, delivering clinically integrated care, for the past eight years. This ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in ... 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced ... 2017. , The annual award competition recognizes editorial and design excellence across a range ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite ... program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... 28, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), ... call and webcast on Friday, November 3, 2017, beginning ... ending at approximately 8:30 a.m. (CDT) / 9:30 a.m. ... 2017 financial performance and guidance for 2018, Hill-Rom executives ... enhance operational performance, and long-range financial outlook through 2020. ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/22/2017)... 2017 AVACEN Medical (AVACEN) announced that its ... helping those with the widespread pain associated with fibromyalgia ... in Essex, England commented, "I ... experiencing no sleep at all, tremendous pain, with every ... recommend [the AVACEN 100] enough, how this has and ...
Breaking Medicine Technology: