Navigation Links
Protection for stressed-out bacteria identified
Date:10/8/2008

An international team of researchers is a step closer to understanding the spread of deadly diseases such as listeriosis, after observing for the first time how bacteria respond to stress.

The research, published in the October issue of the prestigious international journal Science, details how a huge molecule called a stressosome protects bacterial cells from external stress and danger.

Scientists from the University of Newcastle in Australia, and Newcastle University and Imperial College in the United Kingdom, collaborated on the discovery.

Associate Professor Peter Lewis from the Faculty of Science and Information Technology at the University of Newcastle in Australia said until now, researchers had not fully understood how bacteria responded to stress and potential danger.

"It is important to understand the changes that occur when bacteria are under stress as this is the point at which they are likely to become most infectious.

"The protein molecules that make up the stressosome are found in a very wide range of bacteria. Some of these bacteria cause diseases such as listeriosis that has a 30 per cent mortality rate, and melioidosis that has a mortality rate as high as 90 per cent and is a significant health problem in northern Australia and south-east Asia.

"With bacteria becoming increasingly resistant to antibiotics, understanding how the stress response is controlled could lead to the development of drugs that help prevent bacterial infection from occurring."

Lead author of the Science paper, Professor Rick Lewis from Newcastle University in the United Kingdom, said the team used groundbreaking techniques to observe the stressosomes. Electron microscopy techniques were developed by Professor Marin van Heel of Imperial College and Associate Professor Peter Lewis developed the fluorescence microscopy imaging techniques.

"We knew that when bacteria were stressed, a warning signal would be sent from the surface to the inside of the cell. The stressosome would then respond by triggering new proteins in the cell to react to the stress.

"Our latest work has revealed the structure and number of stressosomes per cell. This has helped us understand how quickly the stressosomes respond to external stresses and prepare the cell to adapt to changes in its environment and ensure its survival."


'/>"/>

Contact: Blythe Hamilton
Blythe.Hamilton@newcastle.edu.au
61-249-216-856
Research Australia
Source:Eurekalert

Related medicine news :

1. Survey reveals disparities in skin cancer knowledge, protection among high school students
2. Scientists Develop Natural Protection for Stored Foods
3. Despite overeating, morbidly obese mice gain protection against diabetes
4. DuPont Focused on Meeting Global Demands for Greater Safety & Protection
5. Residual fetal cells in women may provide protection against breast cancer
6. Hospital Coalition Says Governors No-Fault Bill Signing Provides a Great Protection for Florida Consumers
7. Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients
8. Long Term Care Newsletter Debuts, Published by LTC Financial Partners; Advice on Living Better, Not Just Longer, With Financial Protection
9. Abbotts Environmental Protection Initiatives Again Recognized by the State of Illinois
10. Safe Sex Passport Launches to Provide Breakthrough Protection Against STDs and HIV
11. URAC Names Medco as a Finalist in First-ever Best Practices in Consumer Empowerment and Protection Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... ... December 09, 2016 , ... Groth Family Insurance, a ... Richland, is initiating a charity drive to support the family of Cindy Hendrickson, ... collision. , On October 29th of this year, Cindy Hendrickson swerved to ...
(Date:12/9/2016)... ... December 09, 2016 , ... Sober College, the ... the grand opening of the Sober College Robert Pfeifer Memorial Learning Center at ... 2-3, and was attended by an overwhelming amount of alumni, family, colleagues and ...
(Date:12/9/2016)... ... ... "I had a terrible time trying to get my grandson to use his ... had a more child-friendly design, then children would be more likely to look forward ... avoid the need to deliver medication via a nebulizer mask. The design will not ...
(Date:12/8/2016)... ... December 08, 2016 , ... Russ ... announced the first national #QuackGivesBack campaign which supported local breast cancer organizations during ... franchise-wide Quack Gives Back initiative, and we’re very pleased with the ...
(Date:12/8/2016)... ... December 08, 2016 , ... With the increasing demand for ... In Your Mouth?” (WIYM) campaign to inform dentists and patients about the safety issues ... implant and prosthetic market in the U.S. is projected to reach $6.4 billion in ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... 2016  Diplomat Pharmacy, Inc. (NYSE: DPLO) has been recognized by ... Workplaces National Standard. To learn more about Diplomat,s ... ... ... administered by WorkplaceDynamics, LLC, a research firm specializing in organizational health ...
(Date:12/8/2016)... Connecticut , 8 de dezembro de 2016  A Mederi Therapeutics ... terapia Stretta, um tratamento não cirúrgico para a doença do refluxo gastroesofágico (DRGE). ... ... Live Stretta procedure performed and ... of Endoscopy at Wuhan Union Hospital ...
(Date:12/8/2016)... Pa. , Dec. 8, 2016  A new ... reports that the use of opioid therapy to treat ... increase the likelihood of more harmful consequences, including death. ... , M.D., and Zankhana Mehta , M.D., authored ... research on chronic opioid therapy. The study was published ...
Breaking Medicine Technology: