Navigation Links
Prostate cancer treatment linked to higher rate of colon cancer, study finds
Date:11/15/2010

ANN ARBOR, Mich. Men treated with hormone-based therapy for prostate cancer faced a 30 percent to 40 percent higher risk of colorectal cancer, compared to patients who did not receive this treatment, according to a new study.

The study looked at use of androgen deprivation therapy, a common type of treatment for prostate cancer that involves blocking the male hormone testosterone through either surgical removal of the testicles or a series of injections. It's been shown to benefit men with advanced cancers, but its benefit for less-advanced disease is unclear. Still, more than half a million men in the United States currently receive this therapy.

Researchers looked at data from 107,859 men aged 67 and older with prostate cancer, identified through the Surveillance, Epidemiology and End Results and Medicare linked database, which provides information about older adults with newly diagnosed cancer. Results of the study were published online in the Journal of the National Cancer Institute.

The study is the first to link androgen deprivation therapy for prostate cancer to an increased risk of colorectal cancer. The researchers found that the risk increased the longer a man received androgen deprivation therapy. Patients who had their testicles removed, a procedure called orchiectomy, had the highest rates of colorectal cancer.

Overall, the risk of colorectal cancer was still low less than 1 percent per year even among orchiectomy patients. But any increased risk should be carefully considered when using androgen deprivation therapy in cases when its benefit is not clear, the researchers say.

"Androgen deprivation therapy still continues to be used in situations where there are not evidence-based studies showing its benefit. When androgen deprivation therapy is clearly known to be beneficial, people should not shy away from using it. But where there's not solid evidence, this is potentially another harm," says lead study author Vahakn B. Shahinian, M.D., M.S., assistant professor of internal medicine at the University of Michigan Medical School and a member of the U-M Comprehensive Cancer Center.

Shahinian stresses that androgen deprivation therapy can be lifesaving for certain men with prostate cancer, and those patients should not hesitate to use it. The study authors suggest that continued routine preventive care, including colorectal cancer screening, is important during prostate cancer treatment.


'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. Advance Toward Test for Aggressive Prostate Cancer
2. DASH FOR DAD Race Series Coming to 11 Cities to Raise Prostate Cancer Awareness
3. Jim Huber to Serve as National Spokesman for Know Your Score: Fight Prostate Campaign at Myrtle Beach Golf Holiday in August
4. Few differences in outcomes between open and laparoscopic prostate surgery
5. Two Surgical Methods Equally Successful for Prostate Cancer
6. Genetic Mutation Linked to Prostate Cancer in Blacks
7. Statins May Benefit Prostate Cancer Patients
8. Demand For Mobile Prostate Cancer Brachytherapy Vendor Programs Continues Into 2010
9. Be a Star Athlete in the Fight Against Prostate Cancer
10. Do men with early prostate cancer commit suicide more frequently?
11. Effective prostate cancer treatment discovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... Beach, FL (PRWEB) , ... February 22, 2017 , ... ... Wrestling Legend Kurt Angle, is now available on the App Store and ... and award-winning mobile apps for the addiction and recovery industry, partnered with Angle to ...
(Date:2/22/2017)... PA (PRWEB) , ... February 22, 2017 , ... A ... some people seem to derive a heart-protective benefit from eating soy foods, while others ... , Japanese men who are able to produce equol—a substance made by some types ...
(Date:2/22/2017)... , ... February 22, 2017 , ... Super-Sod will attend ... 26 event in Athens, Georgia. , A shift from Super-Sod’s simple Athens Home Show ... , For the booth, grass seed plant manager Chris Roquemore constructed furniture from recycled ...
(Date:2/22/2017)... SC (PRWEB) , ... February 22, 2017 , ... ... of several sponsors of the Medical University of South Carolina (MUSC) Center on Aging’s ... Mount Pleasant, SC. “MUSC’s Center on Aging is a tremendous resource in our community. ...
(Date:2/22/2017)... Dallas, Texas (PRWEB) , ... February 22, 2017 ... ... mobile enterprise solutions for supply chain management (SCM) and spend management, today announced ... reduce cost, save time, and simplify expense tracking. , “We are excited ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... Feb 22, 2017 Research and Markets ... Devices Market (Thermometers - Digital, Infrared, Mercury; Trend Indicator):Analysis By Region, ... ... Market is forecasted to grow at a CAGR of 5.33% during ... prevalence of infectious diseases along with surging demand of digital thermometer. ...
(Date:2/22/2017)... Feb. 22, 2017  Bioness, Inc., the leading provider ... the first series of successful StimRouter Neuromodulation System implantations ... Medical Center (Nijmegen, Netherlands ), ... Ireland ), and Kliniek Park Leopold Chirec ( ... continuing, Bioness plans to further support clinicians across the ...
(Date:2/22/2017)... Colo. , Feb. 22, 2017  Aytu BioScience, ... global commercialization of novel products in the field of ... team to up to 42 account managers from 35 ... The sales force expansion is being ... prescriptions and revenues, an indication of increasing acceptance of ...
Breaking Medicine Technology: