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Prostate cancer more likely to return in blacks than whites, but the disease is not more aggressive
Date:10/9/2007

currence, as well as the level of PSA found in the blood of the patients, Freedland said.

We found that African-American men were 28 percent more likely to experience a disease recurrence, said Robert Hamilton, M.D., a urology resident at the University of Toronto and former research fellow at Duke, and lead author on the publication. But when we compared the men who had experienced recurrence, we found that the aggressiveness of the disease was similar across the racial groups.

Although African-Americans may be more likely to see their disease return after treatment, this study points to a trend toward better screening and earlier detection among black men, Freedland said.

We did find that black men were diagnosed at younger ages and had higher PSA levels, but the fact that their disease seemed to be no more aggressive than that of their white counterparts was encouraging, he said. Earlier studies showed that black men had more aggressive disease at the time of diagnosis than other races, suggesting that their tumors were being discovered at more advanced stages.

Screening has apparently improved, but this study paves the way for more work aimed at developing preventive and treatment strategies directed at these genetic and biologic differences, Freedland said.


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Contact: Lauren Shaftel Williams
lauren.shaftel@duke.edu
919-684-4966
Duke University Medical Center
Source:Eurekalert

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