Navigation Links
Prostate cancer increases hip fracture risk by eight times in 50 to 65 year-olds

Men who have prostate cancer are on average four times more likely to suffer a hip fracture, with rates rising to eight times in men aged 50 to 65, according to a study of more than 60,000 men published in the October issue of the urology journal BJU International.

Danish researchers looked at 62,865 men aged 50 and over, with an average age of just under 67.

15,716 had suffered a fracture of some description and 47,149 formed the non-fracture control group.

They discovered that prostate cancer made men 1.8 times more likely overall to suffer a fracture and 3.7 times as likely to suffer from a hip fracture. But the hip fracture risk was eight times higher in men from 50 to 65 years of age. No increased risk of vertebral fractures was found by the research.

Our study showed that more than three per cent of hip fractures in men aged 50 and over can be attributed to prostate cancer says lead researcher Dr Bo Abrahamsen from Copenhagen University Hospital, Gentofte. And the risk remains even when men have recovered from the disease.

The researchers - urologists and endocrinologists from Danish hospitals attached to the University of Southern Denmark and Copenhagen University - now plan to establish a multi-centre initiative focussing on the early diagnosis and treatment of osteoporosis in men with prostate cancer.

Prostate cancer is now the cancer that men are most likely to develop and is a leading cause of male deaths in Europe and the USA stresses Dr Abrahamsen.

American research has also shown that men have a 17 per cent chance of prostate cancer during their lifetime. And Danish research has discovered that deaths from the disease have more than tripled since the Second World War.

Medical advances are improving survival rates, but the downside is that treatment can lead to osteoporosis, where the bone loses density and becomes more fragile. This is turn increases the risk of fractures.

The researchers used data from the Danish National Hospital Discharge Register, the National Bureau of Statistics and the National Prescription Database to identify patients aged 50 and over who had suffered a fracture. They then used the same data to identify an age-matched control group.

Our research showed that the increased fracture risk became apparent in the early stages after diagnosis and remained pronounced even in long-term survivors says Steen Walter, Professor of Urology at Odense University Hospital.

Men who received hormone therapy (ADT) or had their testicles surgically removed to slow the progression of the disease were 1.7 times more likely to suffer a fracture.

The authors point out that the research only covered the 15 per cent of ADT doses issued on prescription. The majority of the doses are issued by hospital departments, which means they cannot be traced to individual patients. So the actual impact of ADT on national fracture levels could be even greater.

Other issues were also found to lead to increased fracture rates.

The study showed that the men in the fracture group were almost three times as likely as the control group to have suffered a previous fracture. They were also more likely to live alone and be in a lower income group says Dr Abrahamsen.


Contact: Annette Whibley
Blackwell Publishing Ltd.

Related medicine news :

1. Cancer Doctors Okays Controversial Prostate Therapy
2. More Accurate "PROSTATE CANCER" Test can save Unnecessary Biopsies
3. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
4. Better prostate cancer detection
5. Protective effects of tomatoes in prostate cancer
6. Early detection of prostate cancer
7. Prevention of Prostate Cancer
8. Low grade prostate cancer may be treated with mild treatment
9. British MPs Say Prostate Cancer Receives Low Priority in the NHS
10. Diagnosing Prostate Cancer is Harder in Obese Individuals
11. Fingerprinting prostate cancer
Post Your Comments:
(Date:11/26/2015)... (PRWEB) , ... November 26, 2015 , ... ... American Express Travel Representative. As a franchise owner, Somu now offers travelers, value ... cruise, destination wedding packages, private cruise sales, as well as, cabin upgrades and ...
(Date:11/26/2015)... , ... November 26, 2015 , ... PRMA Plastic Surgery ... 19, 2015, our surgeons performed their 6,000th free flap breast reconstruction surgery! , “What ... up every day excited to rebuild lives and it’s an honor to have served ...
(Date:11/26/2015)... ... November 26, 2015 , ... Health-E-minds ... collaborated with Women’s Web – an online resource for Indian women looking ... and emotional well-being relationship, life balance, stress, professional development, and lifestyle. Health-E-minds ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... accessible for all, Water For Empowerment ™ attracts volunteers together who want ... water by empowering women as key stakeholders in the process. The non-profit launched ...
(Date:11/25/2015)... Neb. (PRWEB) , ... November 25, 2015 , ... ... staffing companies, has been recognized once again for its stellar workplace culture with ... to Work.” , Medical Solutions’ Cincinnati office was named a finalist ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... --> adds "Global ... and "Investigation Report on China Repaglinide ... 2021 forecasts data and information to ... . --> ...
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 ... the addition of the "2016 Future Horizons ... Monitoring (TDM) Market: Supplier Shares, Country Segment Forecasts, ... offering. --> ... comprehensive analysis of the Italian therapeutic drug monitoring ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Cell Surface Marker Testing ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
Breaking Medicine Technology: