Men who have prostate cancer are on average four times more likely to suffer a hip fracture, with rates rising to eight times in men aged 50 to 65, according to a study of more than 60,000 men published in the October issue of the urology journal BJU International.
Danish researchers looked at 62,865 men aged 50 and over, with an average age of just under 67.
15,716 had suffered a fracture of some description and 47,149 formed the non-fracture control group.
They discovered that prostate cancer made men 1.8 times more likely overall to suffer a fracture and 3.7 times as likely to suffer from a hip fracture. But the hip fracture risk was eight times higher in men from 50 to 65 years of age. No increased risk of vertebral fractures was found by the research.
Our study showed that more than three per cent of hip fractures in men aged 50 and over can be attributed to prostate cancer says lead researcher Dr Bo Abrahamsen from Copenhagen University Hospital, Gentofte. And the risk remains even when men have recovered from the disease.
The researchers - urologists and endocrinologists from Danish hospitals attached to the University of Southern Denmark and Copenhagen University - now plan to establish a multi-centre initiative focussing on the early diagnosis and treatment of osteoporosis in men with prostate cancer.
Prostate cancer is now the cancer that men are most likely to develop and is a leading cause of male deaths in Europe and the USA stresses Dr Abrahamsen.
American research has also shown that men have a 17 per cent chance of prostate cancer during their lifetime. And Danish research has discovered that deaths from the disease have more than tripled since the Second World War.
Medical advances are improving survival rates, but the downside is that treatment can lead to osteoporosis, where the bone loses density and becomes more fragile. This is turn increases the risk of fractu
|Contact: Annette Whibley|
Blackwell Publishing Ltd.