Navigation Links
Prostate cancer immunotherapy significantly prolongs survival in men with advanced prostate cancer
Date:4/29/2009

CHICAGO, ILSipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago. These data from the Phase 3 Immunotherapy for Prostate AdenoCarcinoma Treatment (IMPACT) study were presented during the meeting's Late Breaking Science Forum.

Compared to placebo, sipuleucel-T extended median survival by 4.1 months and improved three-year survival by 38 percent. Sipuleucel-T successfully exceeded the pre-specified level of statistical significance defined by the study's design and reduced the overall risk of death by 22.5 percent compared to placebo (p-value=0.032). More than 500 patients were enrolled in the IMPACT trial, a multi-center, randomized, double-blind, placebo-controlled study evaluating men with asymptomatic or minimally symptomatic, metastatic, androgen-independent prostate cancer. The primary endpoint was overall survival.

Researchers are encouraged by the findings, citing an impressive effect on long-term survival for patients, compared to placebo.

"The ability to boost survival for patients is the gold standard endpoint in prostate cancer clinical trials," said AUA spokesperson Ira D. Sharlip, MD. "The ability to give these patients both increased survival and possibly, improved quality of life, is very important."

Sipuleucel-T is an investigational therapy for men with androgen-independent prostate cancer. It is an active cellular immunotherapy designed to use live human cells to boost a patient's immune system to elicit a long-lasting response against cancer.


'/>"/>

Contact: Wendy Isett
wisett@auanet.org
410-977-4770
American Urological Association
Source:Eurekalert

Page: 1

Related medicine news :

1. Statins alter prostate cancer patients PSA levels
2. Living and Loving with Prostate Cancer: Men Deserve Better
3. Data Show Dutasteride Reduces Prostate Cancer Diagnosis in Men With Increased Risk
4. AUA Counters Mainstream Recommendations with New Best Practice Statement on Prostate-Specific Antigen Testing
5. Heart, Bone Problems May Follow Prostate Cancer Treatment
6. Prostate Study Shows BOTOX May Be Safe, Effective Method for Managing Benign Prostatic Hyperplasia
7. Prostate cancer therapy increases risk of fractures and cardiovascular-related death
8. Statins Guard Against Prostate Cancer
9. Statins may exert influence on prostate cancer growth by reducing inflammation
10. Major statin study reveals several important findings for reducing prostate cancer and disease
11. Varian Medical Systems to Exhibit Full Spectrum of Prostate Cancer Treatment Technologies at the American Urological Association Meeting in Chicago
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... 28, 2014 The National League for ... DrPH, MN, RN, FAAN, became the inaugural director of ... Advancement of the Science of Nursing Education , effective ... comprise the NLN Home for Transformative Excellence, established with ... year ago. , Under Dr. Dennis’s leadership, the ...
(Date:8/27/2014)... August 28, 2014 Recently, Skmen.com, a ... designs of celebrity bodycon dresses . The company ... has thousands of trendy items in stock and ready ... casual outfits, long sleeve sweater dresses and so forth. ... stunning colours. , “We are proud to announce ...
(Date:8/27/2014)... 2014 Philadelphia, PA. Inc. magazine ... Inc. 500 list, an exclusive ranking of the nation’s ... comprehensive look at the most important segment of the ... gained early exposure as members of the Inc. 500 ... , “Some of world’s greatest companies have had ...
(Date:8/27/2014)... All Canada Goose Parkas from ... from classic to modern. With unique detailing such as buttons, ... is a step up in opulence. Recently, the company has ... for 2014. , True enough, the new assortment ... discounts (up to 28% off) on all these brand new ...
(Date:8/27/2014)... Locating an approximate price for an insurance ... information before rates would be viewable. The Quotes Pros ... are distributed online using its policy locator at ... adult has access to review using the national finder ... for quotation distribution built in 2013 is now programmed ...
Breaking Medicine News(10 mins):Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 2Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 3Health News:Betty Pierce Dennis to Lead NLN/Chamberlain College of Nursing Center for the Advancement of the Science of Nursing Education 4Health News:Skmen.com Unveils Its New Celebrity Bodycon Dresses for Its Loyal Customers 2Health News:Inc Magazine Unveils 33rd Annual List of America's Fastest-Growing Private Companies - the Inc. 500 2Health News:CanadaGooseJackor.nu: 2014 Canada Goose Banff Parkas At Discounted Prices 2Health News:Life Insurance Quotes for Term Policies Now Found at Insurer Website Online 2
... more likely than others to introduce their infants to cow,s ... children at risk of health complications, according to a study ... and Poverty, New York. The study showed that women ... during their first or second trimester of pregnancy -- from ...
... Steven Reinberg HealthDay Reporter , MONDAY, June 28 ... cholesterol levels, statins don,t appear to reduce the chances of ... scientists have found. Statins are used widely to treat ... with heart disease and -- in more recent years -- ...
... ... California based laboratory equipment repair and instrument calibration services company, has been formally ... calibration lab., , ... (PRWEB) June 29, 2010 -- Beginning in 2009, the AL-TAR Quality ...
... Advanced ... percutaneous—or through the skin—techniques, according to a new study appearing online and in the ... ... 2010 -- Advanced imaging technologies have helped shift biopsy techniques away from more invasive ...
... Advanced imaging technologies have helped shift biopsy techniques away ... skintechniques, according to a new study appearing online and ... Radiology . Biopsythe removal of cells or ... The first percutaneous needle biopsy of the liver was ...
... A literature review, led by Dr. Joseph Lee, published in the ... Academy of Orthopaedic Surgeons ( JAAOS ) suggests that a ... back and leg pain in adults, but surgery is not for ... low back pain at some point in their lives Disks, ...
Cached Medicine News:Health News:WIC might prevent mothers from feeding cow's milk too early 2Health News:Statins May Not Be as Helpful for Those Without Heart Disease 2Health News:Statins May Not Be as Helpful for Those Without Heart Disease 3Health News:AL-TAR Services, Inc. Laboratory Is Now Accredited For ACLASS Standards 2Health News:Use of Less Invasive, Imaging-Guided Biopsies on the Rise 2Health News:Use of Less Invasive, Imaging-Guided Biopsies on the Rise 3Health News:Use of less invasive, imaging-guided biopsies on the rise 2Health News:Lower back pain and surgery 2
(Date:8/27/2014)... Aug. 27, 2014  Decision Resources Group finds ... oncology, hematology-oncology, rheumatology, gastroenterology, endocrinology and nephrology) expect ... a biosimilar has been assessed in to be ... choose to prescribe. Other key ... Acceptance of Biosimilars Across Physician Specialties ...
(Date:8/27/2014)... Fla. , Aug. 27, 2014 ... today that it has released a preview of its ... the pharmaceutical industry avoid drug shortages and maintain a ... The Plan, a first for the ... and biopharmaceutical industry members and describes how industry can ...
(Date:8/27/2014)... YORK , Aug. 27, 2014 Reportlinker.com ... in its catalogue: Baby Food Eastern Europe ... Summary "Baby Food Eastern Europe 2014" is a new ... demand prospects in Eastern Europe , ... various trends. This report also examines trends which are ...
Breaking Medicine Technology:Surveyed Physicians Expect to Choose Between Future Biosimilars Based on Robustness and Number of Clinical Trials 2ISPE Releases First Look at its Plan to Prevent Drug Shortages 2ISPE Releases First Look at its Plan to Prevent Drug Shortages 3ISPE Releases First Look at its Plan to Prevent Drug Shortages 4Baby Food Eastern Europe 2014 2Baby Food Eastern Europe 2014 3Baby Food Eastern Europe 2014 4Baby Food Eastern Europe 2014 5Baby Food Eastern Europe 2014 6Baby Food Eastern Europe 2014 7Baby Food Eastern Europe 2014 8
... Pulse Oximeter monitors SpO2, pulse ... is designed to provide fast, ... The device rejects spontaneous motion ... operator of excess artifacts and ...
... Radical can operate in two additional ... be removed, creating a fully featured handheld ... also be used to upgrade existing equipment ... additinal hardware or software upgrades to improve ...
Halogen-free immersion oil based on ester oil....
Immersion Oil, 150 cs...
Medicine Products: