Navigation Links
Prostate cancer cells thrive on stress
Date:1/25/2013

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer. In this issue of the Journal of Clinical Investigation George Kulik and colleagues at Wake Forest University examined the relationship between stress and cancer progression in a mouse model of prostate cancer. Kulik and colleagues found that mice that had been subjected to stress (exposed to the scent of a predator) exhibited a significantly reduced response to a drug that induces cancer cell death compared to their unstressed counterparts. Administration of adrenaline also blocked cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer. These findings suggest that beta-blockers, which are used for the treatment of high blood pressure and block the effects of adrenaline, could increase the efficacy of anti-cancer therapies. In a companion commentary, Anil Sood and colleagues at MD Anderson Cancer Center discuss additional studies that will be required to move these findings from bench to bedside.


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related medicine news :

1. Emotional stress reduces effectiveness of prostate cancer therapies in animal model
2. Stigma stymies prostate cancer screening, treatment in Ghana
3. Personal epigenetic signatures found consistent in prostate cancer patients metastases
4. Kaiser Permanente study: Change in PSA levels over time can help predict aggressive prostate cancer
5. Chinese Herbal Medicine Can Reach into Prostate Gland and Treat Prostatitis Successfully As A New Option for Prostatitis Sufferers, States Wuhan Dr.Li's Clinic
6. High fiber diet prevents prostate cancer progression
7. How prostate cancer therapies compare by cost and effectiveness
8. Some Complain of Shorter Penis After Prostate Cancer Treatment: Study
9. Some men voice complaints of shortened penis following prostate cancer treatment
10. New Lawsuit on Avodart Prostate Cancer: Now, AttorneyOne Can Provide Advice
11. Dr. Gary McClain of JustGotDiagnosed.com Addresses Prostate Cancer Support Group
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from PsychTests.com reveals that behind the tendency to set ...
(Date:6/24/2016)... ... ... was in a crisis. Her son James, eight, was out of control. Prone to extreme ... “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was ... other children and say he was going to kill them. If we were driving ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Comfort Keepers® of ... Cancer Society and the Road To Recovery® program to drive cancer patients to and ... other adults to ensure the highest quality of life and ongoing independence. Getting ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, affiliated ... Weintraub as a prominent plastic surgeon and the network’s newest partner. , ... most handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s ... June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... helping service members that have been wounded in battle and their families. Venture Construction ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
(Date:6/23/2016)...  In a startling report released today, National Safety Council ... a comprehensive, proven plan to eliminate prescription opioid overdoses. ... states are tackling the worst drug crisis in recorded U.S. history, ... Kentucky , New Mexico , ... the 28 failing states, three – Michigan , ...
Breaking Medicine Technology: