Navigation Links
Prostate cancer advance could improve treatment options
Date:2/12/2014

don, and at UEA.

Dr Clark said: "By the age of 60, the majority of men will have signs of prostate cancer. However, only a small proportion of men will die of the disease. The question is - which of these cancers are dangerous and which are not? Deciding which cancers are going to progress and kill the patient is key to effective patient treatment."

"Prostate cancer thrives on male hormones, and cutting the supply of hormones to the cancer is a main avenue of therapy. Prostate cancer only kills the patient when it becomes immune to these therapies. A third of these killer cancers are immune to therapy because they have boosted the number of male hormone receptor (AR) genes in their DNA. This gene boosting, also known as amplification, has been thought to be a response of the tumour to the hormone reduction therapy itself.

"Our research has shown that an early form of this hormone-gene boosting is present in a number of prostate cancers that have never been treated with hormone reduction therapy. We think that it is these cancers that will grow and kill the patient.

"This discovery can be used to identify these killer cancers in patients much earlier than is currently possible. Patients could then be selected for more aggressive therapy before the cancer has developed full immunity."

The research team looked at biomarkers from almost 600 patients prior to hormone-withdrawal therapy. But the method of identification used was labour intensive and time consuming. Developing ways of identifying patients for early therapeutic intervention will be key to implementing this discovery in the clinic. The research team are currently looking at more rapid ways of identifying patients that will develop aggressive cancer.


'/>"/>

Contact: Lisa Horton
press@uea.ac.uk
01-603-593-496
University of East Anglia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Mayo Clinic identifies a key cellular pathway in prostate cancer
2. 3D mapping biopsy finds 3x prostate cancer of ultrasound-guided biopsy
3. Prostate cancer signal reawakens sleeper agent cells in bones
4. Scientists develop powerful new animal model for metastatic prostate cancer
5. Researchers identify possible explanation for link between exercise & improved prostate cancer outcomes
6. Melatonin may lower prostate cancer risk
7. Researchers develop tool to determine individual risk of prostate cancer overdiagnosis
8. Increased risk of prostate cancer in African-American men; implications for PSA screening
9. Cleveland Clinic receives grant to study role of DNA damage in treatment-resistant prostate cancer
10. Prosvent Emerges As Preferred Treatment For Enlarged Prostate
11. Pain drugs used in prostate gland removal linked to cancer outcome, Mayo Clinic-led study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 Deer Path of Huntley -- ... Day Happy Hour from 3 p.m. to 4 p.m. on Feb. ... in Huntley, Illinois, serves adults with physical disabilities between the ages ... Valentine's Day treats, games and sweetheart-themed karaoke. , For more information ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Liberty University has ... (M.A.) program from the Council for Accreditation of ... part of Liberty’s Center for Counseling & Family Studies ... dean of the university’s new School of Behavioral Sciences. Prior ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The City of West ... 10 a.m., to commemorate the 42nd anniversary of the Supreme Court ... , “It’s been 42 years since the Roe vs. Wade decision ... still as present as ever,” said City of West Hollywood Councilmember ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release of ... kids with cancer. The Chemo Duck App, available on iTunes for ... games to help children of all ages living with cancer adjust ... kids entertained, educated and at ease while waiting for clinic visits ...
(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2
... RNA molecules that have only about 20 nucleotides and do ... cells by binding to target messenger RNAs the instructions ... protein. In cancer, the production of some miRNAs is often ... activity of cancer-promoting genes. A key molecule in ...
... Conference on Cell Therapy for Cardiovascular Disease is a ... of cell-based therapies for the repair and regeneration of ... such as diabetes and stroke. This year,s conference will ... to commercialization, highlighting the status of molecular, cell, and ...
... Among people recently infected with HIV, immediate antiretroviral therapy ... new study published in the Journal of Infectious ... of ART during early HIV-1 infection remain unproven, the ... Christine Hogan, MD, of the Medical College of Wisconsin ...
... Reinberg HealthDay Reporter , THURSDAY, Dec. 15 (HealthDay ... for all children in the United States, a new study ... have dropped slightly in the past five years, particularly among ... rate is only 1.2 percent, it,s still the largest drop ...
... International Association for the Study of Lung Cancer (IASLC) ... the international lung cancer community on how we should ... initial statement to the National Lung Screening Trial (NLST) ... April and also hosted a CT screening workshop with ...
... The University of Washington Medical Center was recently granted ... Center (ANCC) for its excellence in nursing practice and ... UWMC has achieved this status, making it the only ... level of recognition. The Magnet award is the highest ...
Cached Medicine News:Health News:No brakes on breast cancer cells 2Health News:Global conference on stem cell therapy to be held Jan. 25-27, 2012 in New York City 2Health News:Study suggests early ART in recently HIV-infected patients preferable to delayed treatment 2Health News:NYC Sees Drop in Child Obesity; Can Other Cities Do Same? 2Health News:NYC Sees Drop in Child Obesity; Can Other Cities Do Same? 3Health News:NYC Sees Drop in Child Obesity; Can Other Cities Do Same? 4Health News:IASLC sets up committee to move CT lung cancer strategic screening forward 2
(Date:1/23/2015)... and DUBLIN , Jan. 23, 2015 ... with KRS Global Biotechnology, Inc. for the compounding, packaging and ... for shipment in the United States . ... Outsourcing Facility capable of compounding naltrexone tablets in various strengths ...
(Date:1/23/2015)... 2015  Pete Rose, baseball,s all-time hits leader, is the new ... Myoflex, Ducere Pharma has announced. "Pete,s a Hall ... have him on board with Myoflex," said Ducere Pharma Chief ... player who is known across all generations. The passion and ...
(Date:1/23/2015)... , Jan. 23, 2015  Now available for sale, ... 7,849,611) support that prevents ankle sprains by cushioning the ... it fits securely around the outside of any shoe ... & comfort while still offering protection against sprains. With ...
Breaking Medicine Technology:Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4Pete Rose bets on Myoflex to relieve aches and pains 2The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2
... a cool-running, energy efficient LEDs (Light Emitting ... to see without affecting the darkened refracting ... maintenance free so you'll never need to ... with a limited lifetime warranty, the best ...
The CT100 mounts conveniently on your slit lamp and can be positioned in front of your patient as required. The prism is viewed through the left microscope objective. The tonometer can be removed fro...
... Patients who need punctal ... dry eye relief. They also ... be as comfortable and as ... why Alcon punctal plugs are ...
... Only Heartlab delivers the performance ... cardiovascular information management systems. As ... and services set the benchmark. ... functionality, high-speed performance and technological ...
Medicine Products: