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Prostate Hormone Therapy May Up Heart Risks
Date:12/7/2009

realize that there can be significant problems in terms of cardiovascular risk. So the lesson is that if you start the therapy early, you should be sure that there is increased survival because there is a downside."

Dr. Eric A. Klein, chairman of the Cleveland Clinic Glickman Urological and Kidney Institute, said that the study "is confirmatory of a lot of other, smaller studies.

"There is a growing realization that we cannot use androgen deprivation therapy in a haphazard fashion," Klein said. "It does save lives or delay progression for men with metastatic prostate cancer so the trade-offs there are reasonable. But in many other cases, the downside probably exceeds the benefit."

More information

The U.S. National Cancer Institute has more on prostate cancer.



SOURCES: Nancy L. Keating, M.D., M.P.H., associate professor, medicine and health care policy, Harvard Medical School, Boston; Peter Albertsen, M.D., professor and chief, division of urology, University of Connecticut Health Center, Farmington, Conn.; Eric A. Klein, M.D., chairman, Urological and Kidney Institute, Cleveland Clinic, Cleveland; Dec. 7, 2009, Journal of the National Cancer Institute, online


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