Prostate Cancer Active Surveillance Protocol Clinical Trial Conducted by NorthShore University Hea...(the only prostate cancer active surveill...),Health

Date:6/15/2009

the only prostate cancer active surveillance clinical trial in the Chicago area and one of only a few in the U.S. Men enrolling in this institutionally approved trial are followed closely without initial treatment with the expectation to intervene if the cancer progresses.

Charles B. Brendler, MD, Co-Director of the NorthShore University HealthSystem Prostate Cancer Center, says, "Prostate cancer is generally a slow growing disease. After age 75, you may do more harm than good in screening men for prostate cancer because, when an early cancer is found, men may feel compelled to seek treatment. As a result, they often end up with serious side effects and no gain in terms of survival."

Dr. Brendler refers to the results of the American and European prostate cancer screening trials published in the March 26, 2009, issue of New England Journal of Medicine. Both trials found that PSA screening did not reduce deaths from prostate cancer during the first 10 years after screening was begun. He says, "The European investigators estimated that you have to diagnose and treat approximately 48 men in order to prevent one man from dying from the disease.

Dr. Brendler continues, "Each treatment is associated with its own set of risks. Whether it is surgery, radiation or hormone therapy, treatment can profoundly affect a man's quality of life. If we can tell which cancers are non-aggressive and ca
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