Navigation Links
Prospective study finds many children with retinoblastoma can safely forego adjuvant chemotherapy
Date:3/4/2013

reserved in the other eye. However, some patients remain at risk of disease spreading and recurrence.

To estimate the risk of disease recurrence and metastasis, doctors examine the surgically removed eye under a microscope and classify the tumor as either low-, intermediate-, or high-risk. All patients whose tumors are considered high-risk receive intensive postoperative chemotherapy and radiation therapy. There is no general consensus, however, on the need for adjuvant therapy and the optimal treatment approach for patients in the other two risk categories. Therefore, protocols for adjuvant chemotherapy use in these patient groups have varied widely.

"Our study confirms that it is not necessary to give adjuvant treatment to many children with unilateral retinoblastoma," said lead study author Isabelle Aerts, MD, a pediatric oncologist at Institut Curie in Paris, France. "I think that our results will help establish the standard of care for such patients, reducing variations in postoperative chemotherapy protocols."

In the present study, 123 patients with unilateral, non-hereditary retinoblastoma were assigned to one of three risk groups according to previously established criteria. The median age at the time of eye removal surgery was 23 months. The 70 patients with low-risk disease received no postoperative chemotherapy; the 52 patients with intermediate-risk disease received four courses of adjuvant chemotherapy (etoposide, carboplatin, vincristine, cyclophosphamide), and the only patient with high-risk disease received six courses of high-dose adjuvant therapy (etoposide, carboplatin, thiotepa, vincristine, and cyclophosphamide).

At a median follow-up period of 71 months, all patients were alive. None of the patients experienced disease worsening, relapse, distant metastasis or secondary cancers. The adjuvant chemotherapy was safe overall. These data confirm that the specific regimens administered in this study, which are already being used
'/>"/>

Contact: Nicole Racadag
nicole.racadag@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Certain Sleep Aids May Raise Hip Fracture Risk in Nursing Homes: Study
2. Daily-use HIV prevention approaches prove ineffective among women in NIH study
3. Study of tenofovir vaginal gel shows daily dosing ineffective due to lack of adherence
4. Pregnancy Boosts Size of Womens Feet, Study Finds
5. Unhealthy drinking widespread around the world, CAMH study shows
6. Vanderbilt study finds maternal diet important predictor of severity for infant RSV
7. Bel Marra Health Reports on a New Study: Software Originally Used for Star Gazing Now Being Used to Analyze Breast Cancer Tissue
8. Growing Old in Suburbia: A Challenge for our Nation’s Elderly - A North Shore-LIJ Health System Study
9. Kids, Seniors Prone to MRSA Infections Depending on Season: Study
10. Study confirms safety of colonoscopy
11. Cancer doesnt change young girls desire to have children, Moffitt Cancer Center study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2015)... (PRWEB) March 29, 2015 Final ... new transition from Pixel Film Studios, entitled TranSports. ... made exclusively for Final Cut Pro X,” said Christiana ... users the tools needed to effortlessly transition using this ... TranSports, a new and uniquely styled transition pack for ...
(Date:3/28/2015)... Rocket Pure , a manufacturer of natural body ... new natural sunscreen. They are offering the sunscreen in ... come with a bonus lip balm sunscreen. , The new ... Click to see the natural sunscreen on Amazon . ... made with non-nano zinc oxide and provides broad-based protection against ...
(Date:3/28/2015)... was featured on NewsWatch as part of its monthly ... coolest applications on the market for iOS, Android, and ... expert, conducted the app review and shared with viewers ... knights, nature, and peasants. , The first endless ... The popularity of these games grew over the years, ...
(Date:3/28/2015)... 2015 Thousands of transvaginal mesh ... C.R. Bard, Inc. continue to move forward in ... Southern District of West Virginia, where Bernstein Liebhard ... Plaintiffs’ Steering Committee. According to an Order ... defendants named in those lawsuits leave to amend ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 India ... coverage is made available to all visitors who purchase ... immediately. All members are encouraged to purchase the insurance ... avoid lack of proper coverage for pre-existing medical conditions. ... one or two medical conditions with serious consequences to ...
Breaking Medicine News(10 mins):Health News:Introducing TranSports for Final Cut Pro X Users from Pixel Film Studios 2Health News:Rocket Pure Releases New Natural Sunscreens For Athletes 2Health News:Rocket Pure Releases New Natural Sunscreens For Athletes 3Health News:A Grim Endless Runner Game Was Featured on NewsWatch Television on January 30, 2015 2Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 2Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 3Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 4Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 2Health News:India Network Health Insurance Today Announces New Eligibility Criteria for Pre-existing Condition Health Insurance Coverage for Visitors to the United States 3
... ... ... ... ...
... link between breathing in dirty air and heart problems ... to the air pollution particles caused by traffic has ... researchers say. , In the new report, researchers analyzed ... who were assessed every four years between 1995 and ...
... ... whether anyone should continue driving them before having them fixed. , ... New York (PRWEB) March 4, 2010 -- In one of the latest ... , Jerry Silver, 86, lost control of his car and collided with two parked vehicles before ...
... illness may extend or shorten life, study finds , ... lead to longer survival for ovarian cancer patients, U.S. ... with incident epithelial ovarian cancer, the researchers found that ... alone, and healthy grain consumption were associated with longer ...
... ... ... ... ...
... The American Society of Hematology (ASH) announces the 2010 ... to support hematologists who have chosen a career in ... that critical period required for completion of training and ... awards are made possible through grants from the corporate ...
Cached Medicine News:Health News:SarahCare(R) and Posit Science Corporation(R) Join Forces to Bring Brain Fitness to Seniors at SarahCare(R) of Minnesota 2Health News:SarahCare(R) and Posit Science Corporation(R) Join Forces to Bring Brain Fitness to Seniors at SarahCare(R) of Minnesota 3Health News:SarahCare(R) and Posit Science Corporation(R) Join Forces to Bring Brain Fitness to Seniors at SarahCare(R) of Minnesota 4Health News:SarahCare(R) and Posit Science Corporation(R) Join Forces to Bring Brain Fitness to Seniors at SarahCare(R) of Minnesota 5Health News:Years of Exposure to Traffic Pollution Raises Blood Pressure 2Health News:New York Personal Injury Lawyers Concerned About Toyota Accident in Queens 2Health News:New York Personal Injury Lawyers Concerned About Toyota Accident in Queens 3Health News:Pre-Diagnosis Diet Linked to Ovarian Cancer Survival 2Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 2Health News:American Dental Association President Testifies Before IOM Committee on Access to Oral Health Care 3Health News:ASH announces 2010 Scholar Award winners 2Health News:ASH announces 2010 Scholar Award winners 3
(Date:3/27/2015)... Report Details  New study shows ... What does the future hold for top companies ... new report shows you potential revenues to 2025, assessing ... 242-page report provides 185 tables, charts, and graphs. Discover ... future market prospects. Our new study lets you assess ...
(Date:3/27/2015)... BROOKFIELD, Wis. , March 27, 2015 /PRNewswire/ ... 40,000 unit shipments of incontinence devices for women. ... terrific, but the most gratifying part is the ... receive from women whose lives have been positively ... , president of InControl. InControl recently ...
(Date:3/27/2015)... , March 27, 2015  RXi ... privately-held MirImmune LLC, today announced that they ... to RXi,s novel and proprietary sd-rxRNA® technology ... immunotherapies. The collaboration has the potential to ... friendly cancer treatments that could be a ...
Breaking Medicine Technology:Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 2Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 3Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 4Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 5Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 6Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 7InControl Medical Surpasses 40,000 Shipments Of Incontinence Devices For Women 2RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 2RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 3RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 4RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 5
... 2011 Aircraft Medical ("Aircraft"), the UK ... an exclusive agreement with Covidien (NYSE: COV ... 2010 revenue of $10.4 billion, and 41,000 employees worldwide. ... will market and distribute Aircraft,s proprietary McGRATH ® ...
... /PRNewswire-iReach/ -- Medical Inflatable Exhibits, Inc. today announced ... MEGA Lungs ™, joining the MEGA Heart™ and MEGA ... models of the human anatomy.  The MEGA Lungs are ... (Photo:   http://photos.prnewswire.com/prnh/20111012/CG83862 ) The MEGA ...
Cached Medicine Technology:Aircraft Medical Signs Multinational Distribution Agreement with Covidien for McGRATH® MAC Video Laryngoscope 2A Breath of Fresh Air for Lung Cancer Awareness Month 2A Breath of Fresh Air for Lung Cancer Awareness Month 3
The pouch is designed to protect the Digitrapper. The pouch strap can be worn on a belt loop or carried in a shoulder strap or backpack configuration....
pHix Strips easily fix the catheter on the nose and are made of microporous tape allowing the skin to breathe....
... The proper gel is ... electrode when working with pH ... The specific chloride ion concentration ... is required for proper function ...
The WaveMax is one of the most flexible stainless steel stents due to its unique wave design and has the lowest effective profile, accommodating a 6F sheath up to 7 mm....
Medicine Products: