Navigation Links
Proposed children's study needs refinement, report finds
Date:6/18/2014

PRINCETON, N.J.A study that would track the health of 100,000 babies to age 21 has been put on hold following the release of an assessment report issued June 16 by the National Research Council and Institute of Medicine (IOM).

While the congressionally mandated report endorses several aspects of the proposed study design of the National Children's Study (NCS), the authors including Sara McLanahan, the William S. Tod Professor of Sociology and Public Affairs at Princeton University's Woodrow Wilson School of International and Public Affairs are critical of the sampling design and study content.

Authorized by the Children's Health Act of 2000, NCS originated after a request by Congress to examine how environmental factors, like social settings and pollution, influence the long-term health of children. The study, managed by an office at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), will recruit 100,000 women and their unborn babies and follow them through age 21. In March 2013, Congress requested that IOM write an assessment of the study design.

While the authors support many aspects of the proposed design, they particularly do not endorse the study's plan to recruit half of the children at birth. Doing so would skew the data obtained, the authors say, due to the scientific importance of prenatal exposures on child development. Instead, the authors recommend recruiting all 95,000 mothers during pregnancy, which can be done for the same cost if 10,000 "convenience samples" are dropped.

"Collecting data on mothers-to-be during the prenatal phase is important and could provide information of paramount importance related to the health, growth and development of U.S. children," said McLanahan, who also directs the Bendheim-Thoman Center for Research on Child Wellbeing. "If carried out successfully, the survey has the potential to be the most comprehensive study of child health and development in the world."

The report authors endorse several of the design features, however, including:

  • The use of a national equal probability sample for a large cohort of births

  • The concept of the study as a data collection platform with a focus on health and development guided by exemplar scientific hypotheses

  • The inclusion of siblings born within a four-year window

  • The collection and storage of biological and environmental samples to permit subsequent analysis

Among its recommendations, the report urges the NICHD to enhance the scientific expertise of the NCS program office by recruiting and contracting with experts in relevant fields from within the National Institutes of Health, other federal agencies and organizations outside of government.

In addition, NICHD should establish an authoritative multidisciplinary oversight structure to review the program office's decisions and establish a mechanism for regular, independent outside review by the qualified organization or a study section like those in NIH.

"Asthma, ADHD and obesity are all on the rise in this country, and probably caused by environmental factors," said McLanahan. "The NCS is designed to collect an unprecedented volume of data on the kinds of environmental and psycho-social exposures both before and after children are born. Moreover, its large size enables the NCS to support analyses of the underlying causes of health disparities across groups defined by race, ethnicity and socioeconomic status, which is an important national health problem identified in the Children's Health Act of 2000."


'/>"/>

Contact: B. Rose Huber
brhuber@princeton.edu
609-258-0157
Princeton University, Woodrow Wilson School of Public and International Affairs
Source:Eurekalert

Related medicine news :

1. Proposed testosterone testing of some female olympians challenged by Stanford scientists
2. Proposed drug may reverse Huntingtons disease symptoms
3. The hidden disorder: Unique treatment proposed for childrens neurological disorder
4. Cause of Chronic Sinusitis Announced; New Actions Proposed by Hydro Med Inc
5. d’Oliveira & Associates Responds to Proposed Legislation That Would Excuse Negligent Doctors’ Admissions From Medical Malpractice Claims
6. Proposed Medicare Essential plan estimated to save $180 billion over 10 years
7. Tenzing Group New Firm Provides Strategic Advice to Mobile Medical Application StartUps on Proposed FDA Regulation
8. New FDA Proposed Tanning Bed Regulations Push For Improved Warnings During National Skin Cancer Awareness Month
9. Warning images for cigarette packs proposed by Europe do not make enough emotional impact
10. Stryker Hip Replacement Lawsuit News: Bernstein Liebhard LLP Notes Upcoming Oral Arguments for Proposed Stryker Hip Recall Multidistrict Litigation
11. Louisiana Shelves Proposed Tax Hike On Cigarettes, But Local Insurance Agents At Cunningham Financial Group Offer Advice For Quitting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... 2017 , ... After raising nearly $30,000 on Kickstarter , about three-times ... at a discounted crowdfunding price on Indiegogo . , “Along with creating an ... to bring a fidget toy to the market that was made of superior quality ...
(Date:5/26/2017)... ... May 26, 2017 , ... “When the Stars Lead Home”: a poignant ... of published author Laura Weigel Douglas, an avid reader who lives in the Pacific ... sometimes feels like Green Hills Adventure Camp. She couldn’t be more grateful. , Twelve-year ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Water damage ... Lee, New Jersey School District had left education officials with a number of critical ... replacement of the flooring had to be accomplished with little or no disruption to ...
(Date:5/24/2017)... ... 24, 2017 , ... NucleusHealth ™, advancing clinical practice ... Food and Drug Administration (FDA) 510(k) clearance for its Nucleus.io ... for medical image management. At the core is patented streaming technology that provides ...
(Date:5/24/2017)... ... May 24, 2017 , ... Myers Jackson is well ... the ability to sell luxury homes anywhere on the planet. The luxury home market ... from Hattiesburg to Houston city-scapes. A quick search of “11 Spyglass Hill Auction will ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... 9, 2017 Zimmer Biomet Holdings, Inc. (NYSE ... today announced it has earned a spot on ... The Company was ranked among 500 U.S. employers as ... Healthcare Equipment and Services. The annual ... anonymous, independent survey of over 30,000 employees across 25 ...
(Date:5/9/2017)... 2017  Semler Scientific, Inc. (OTCQB: SMLR), an ... improve the clinical effectiveness and efficiency of healthcare ... quarter ended March 31, 2017. ... to identify when preventive care options are appropriate, ... heart attacks or strokes occur," said Doug ...
(Date:5/6/2017)... , May 5, 2017   Provista , a proven ... than 200,000 customers, today announced Jim Cunniff as ... of executive and business experience to Provista, including most recently ... in California . He assumed his new ... is a great fit for Provista," says Jody Hatcher ...
Breaking Medicine Technology: