Navigation Links
Propofol's effect on the sciatic nerve: Harmful or protective?
Date:10/31/2013

Propofol is a rapid, but short-acting, intravenous drug that is preferentially used for the induction and maintenance of anesthesia. Propofol can inhibit inflammation and suppress the secretion of the proinflammatory cytokines interleukin-1, interleukin-6 and tumor necrosis factor alpha from astrocytes, and enhance the synthesis and release of the anti-inflammatory cytokine interleukin-10. Consequently, propofol can inhibit damage caused by proinflammatory cytokines and exert protective effects on the central nervous system. A recent study published in the Neural Regeneration Research (Vol. 8, No. 27, 2013) showed that after propofol was injected into the injured sciatic nerve of mice, nuclear factor kappa B expression in the L46 segments of the spinal cord in the injured side was reduced, apoptosis was decreased, nerve myelin defects were alleviated, and the nerve conduction block was lessened. The experimental findings indicate that propofol inhibits the inflammatory and immune responses, decreases the expression of nuclear factor kappa B, and reduces apoptosis. These effects of propofol promote regeneration following sciatic nerve injury.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related medicine news :

1. Young girls more likely to report side effects after HPV vaccine
2. Preteens More Likely to Report HPV Vaccine Side Effects
3. In children born with severe heart defect, surgical management has little effect on neuro outcomes
4. Novel compound demonstrates anti-leukemic effect in zebrafish, shows promise for human treatment
5. Breast cancer patients suffer treatment-related side effects long after completing care
6. Breast Cancer Treatment Side Effects May Last for Years
7. Baldness Drug May Cause Sexual Side Effects: FDA
8. Study examines adverse effects among different radiation therapies for prostate cancer
9. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
10. Pig stomach mucins are effective as anti-viral agents for consumer products
11. LA BioMeds Dr. John Tsuang examines effects of Ibudilast and metamphetamines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Propofol's effect on the sciatic nerve: Harmful or protective?
(Date:9/15/2014)... Transvaginal mesh lawsuits ( http://www.transvaginalmeshlawsuithelp.com/ ) ... in the federal multidistrict litigation now underway in U.S. ... LLP reports. According to documents filed in the proceeding, ... that provides for the severance of several actions in ... affected plaintiffs has objected to severance of the cases. ...
(Date:9/15/2014)... to recent studies, approximately one out of every 40 individuals ... responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that ... University of Missouri have made a recent breakthrough with the ... in animal models of the disease. In April, a patent ... "The strategy our lab is using to fight SMA is ...
(Date:9/15/2014)... Alto, CA (PRWEB) September 15, 2014 ... anniversary since its founding in 2007. To mark the ... local community for supporting the village and helping it ... provides a safe, secure and fun community for seniors. ... to the community and live in their own homes. ...
(Date:9/15/2014)... (HealthDay News) -- Births of multiple babies cost more ... singleton births, researchers report. The researchers suggest that ... (IVF) could ease some of that burden. Over ... tandem with births to older mothers and use of ... of New South Wales, Australia. Their study, published ...
(Date:9/15/2014)... (PRWEB) September 15, 2014 Providing ... Cherry Bekaert LLP (“the Firm”) is ... as a Director with the Firm’s Litigation ... 25 years of experience, Wolf will assist clients ... advisory and transactional advisory matters. He will also ...
Breaking Medicine News(10 mins):Health News:C.R. Bard Transvaginal Mesh Lawsuits Move Forward, With Issuance of New Order in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 2Health News:C.R. Bard Transvaginal Mesh Lawsuits Move Forward, With Issuance of New Order in Federal Multidistrict Litigation, Bernstein Liebhard LLP Reports 3Health News:Researcher develops and proves effectiveness of new drug for spinal muscular atrophy 2Health News:Avenidas Village Celebrates Anniversary 2Health News:Study Ties Multiple Births to Higher Costs, Complications 2Health News:Study Ties Multiple Births to Higher Costs, Complications 3Health News:Cherry Bekaert Expands its Litigation Support Services Team Capabilities with the Addition of Steven Wolf 2Health News:Cherry Bekaert Expands its Litigation Support Services Team Capabilities with the Addition of Steven Wolf 3
... deadly, say authors of a new survey , , TUESDAY, May ... level of driving experience, putting them at risk for accidents ... many teens recognize that drinking and driving don,t mix, many ... having friends in the car. , "We listened to teenagers ...
... Provided for Successfully Tackling This Valuable ... Part of Her ... on their,plates -- from carpool queen to coach, counselor to chef. It,s ... childhood,obesity and inadequate nutrition, many moms have taken on yet another,important role ...
... announced financial,and operating results for its first quarter ended March 31, ... percent to $7.127 billion. -- Net income totaled $170 million, ... year,s first quarter. -- Adjusted EBITDA totaled $1.180 billion, compared ... of 2007. -- Provision for doubtful accounts increased to $888 ...
... 6 , - International Reach of ,Young ... For the first time, a researcher from ... (APA) prestigious "Young Minds in,Psychiatry" awards, which were ... Washington, DC. The awards, supported by an educational ...
... Hope, fundraising efforts honor Marcus,s dog Tasha and her ... life-threatening blood disorder, DENVER, May 6 Racing driver ... 2008 season race proceeds from their new,BMW Z4 M Coupe ... (MAF). All donations to Meisha,s Hope are used to fund ...
... Market Research Reveals, CHICAGO, May 6 ... in the new three-dimensional research study --,Understanding Gluten ... international findings deliver an innovative 360 degree view,of ... qualitative,insights from customers living with food allergies, celiac ...
Cached Medicine News:Health News:Many Teen Drivers Don't Think They're Inexperienced 2Health News:Many Teen Drivers Don't Think They're Inexperienced 3Health News:Got Milk? Campaign Will Recognize and Reward Moms for Their Role as the Family's Chief Health Officer 2Health News:Got Milk? Campaign Will Recognize and Reward Moms for Their Role as the Family's Chief Health Officer 3Health News:HCA Reports First Quarter 2008 Results 2Health News:HCA Reports First Quarter 2008 Results 3Health News:HCA Reports First Quarter 2008 Results 4Health News:HCA Reports First Quarter 2008 Results 5Health News:HCA Reports First Quarter 2008 Results 6Health News:HCA Reports First Quarter 2008 Results 7Health News:HCA Reports First Quarter 2008 Results 8Health News:HCA Reports First Quarter 2008 Results 9Health News:HCA Reports First Quarter 2008 Results 10Health News:HCA Reports First Quarter 2008 Results 11Health News:HCA Reports First Quarter 2008 Results 12Health News:The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China 2Health News:The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China 3Health News:The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China 4Health News:The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China 5Health News:Racing Professional Steve Marcus Pledges Season BMW Proceeds to Morris Animal Foundation's Meisha's Hope Fund 2Health News:80% of Customers Eat Out Less Due to Food Allergies and Celiac / Coeliac Disease Impacting Quality of Life 2
(Date:9/15/2014)... and BRUSSELS , Sept. ... ) and UCB (Euronext Brussels:UCB) today announced results from ... romosozumab in postmenopausal women with low bone mineral density ... designed to work by inhibiting the protein sclerostin, thereby ... were presented at the American Society for Bone and ...
(Date:9/15/2014)... -- myMatrixx has extended its contract with its Medical ... role that includes direct involvement in the myMatrixx clinical ... physiatrist and pain management specialist, published author, and frequent ... is Board Certified in physical medicine and rehabilitation and ... and subspecialty boarded by the American Board of Anesthesia. ...
(Date:9/15/2014)... The Society of Corporate Compliance and ... than 4,500 compliance and ethics professionals from across ... corporate fines and settlements.  The SCALENDAR is designed ... ready reference to demonstrate to employees the consequences ... to help compliance and ethics officers looking for ...
Breaking Medicine Technology:New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 2New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 3New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 4New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 5New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 6New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 7New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 8New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 9New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 10New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 11New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 12New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 13New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 14New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 15myMatrixx Announces Expanded Role for Medical Director Steven P. Stanos, Jr., DO 2More than $55 billion in fines and settlements added by SCCE to its 2015 Corporate Scandal Calendar 2
... Aug. 29, 2011 Elekta announced it has ... treatment control system in the European Union. Integrity ... variable dose rate (CVDR) and interdigitation capabilities for ... complete range of delivery techniques -- such as ...
... Cardium Therapeutics (NYSE Amex: CXM ) ... designed to reestablish compliance with its exchange listing requirements ... of a revenue-generating nutraceutical business designed to expand the ... Company announced the incorporation of MedPodium Health Sciences, Inc., ...
Cached Medicine Technology:New Digital Linear Accelerator Control System Demonstrates Treatment Time Savings of Up to 30 Percent 2New Digital Linear Accelerator Control System Demonstrates Treatment Time Savings of Up to 30 Percent 3Cardium Provides Update on Exchange Listing and Related Business Matters 2Cardium Provides Update on Exchange Listing and Related Business Matters 3Cardium Provides Update on Exchange Listing and Related Business Matters 4Cardium Provides Update on Exchange Listing and Related Business Matters 5
Table mount stabilizer system...
The specially designed table-mounted stepper/stabilizer offers the strength and stability necessary for a flawless delivery of brachytherapy....
... long-pulsed Nd:YAG laser system with a wavelength of ... deep-lying, superficial as well as red and blue ... in patients with darker skin types (1 to ... for general improvement of skin texture. The handpieces ...
... SINON is a Q-switched ruby ... of 694 nm. High Performance ... - This combination of high ... in Q-switched mode effectively destroys ...
Medicine Products: