Navigation Links
Promising therapy for relapsing multibple sclerosis
Date:2/16/2010

MS, that are characterized by abnormal T-cell responses.

Rose and his colleagues performed a randomized, double-blind, placebo-controlled study at 51 centers in the U.S., Canada, Germany, Italy, and Spain. They recruited 230 patients with relapsing MS who were taking interferon beta and randomly assigned them to receive add-on treatment with high-dose daclizumab, low-dose daclizumab, or placebo. The primary objective of the study was to assess whether daclizumab affected MS disease activity by measuring the total number of new or enlarged lesions in the brain during 24 weeks of treatment.

In addition to finding that add-on treatment with high-dose daclizumab resulted in a significantly lower number of new or enlarged MS lesions, the researchers found that patients treated with either high- or low-dose daclizumab had a seven to eight times higher number of immune cells called CD56bright natural killer cells (NK Cells). Previous research has shown that untreated MS patients have lower numbers of these NK cells than healthy individuals.

"Several lines of evidence point to a potential function for CD56bright natural killer cells in regulating the immune system," explains Rose. "This study provides confirmatory data that daclizumab treatment causes an expansion of CD56bright natural killer cells and adds support to the theory that this expansion might mediate some of the effects of daclizumab on reducing multiple sclerosis lesion activity." Further research is needed to clarify whether the risk-benefit of daclizumab is better when the drug is used alone or in combination with interferon beta, as well as to determine the optimum dose and length of treatment needed to see the full therapeutic effects of the drug.

"The CHOICE trial showed that treatment with daclizumab was associated with both a significant reduction in MS lesion formation and a robust increase in important cells that help to regulate the immune system," concludes Ro
'/>"/>

Contact: Dennis Jolley
dennis.jolley@hsc.utah.edu
801-581-5777
University of Utah Health Sciences
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. First blinded study of venous insufficiency prevalence in MS shows promising results
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Promising new neuroimaging techniques for early detection of Alzheimers disease
4. LSUHSC research yields promising stroke treatment
5. Promising New Results On The Added Safety Of Using SmokeStik Electronic Cigarettes In The Bid To Quit Smoking
6. UV LED therapy shows promising results in preventing focal seizures
7. New insights into mushroom-derived drug promising for cancer treatment
8. Carfilzomib Safety Data From Ongoing Phase 2b Pivotal Trial in Relapsed and Refractory Multiple Myeloma Show Promising Safety and Tolerability
9. Promising pharmaceutical agents emerge as sports doping products
10. Pneumonia Drug Promising Against Form of Muscular Dystrophy
11. Health Alliance Announces Promising Nine-Month Results from First Ever Outcome-Based Reimbursement Program for Actonel(R) (risedronate sodium) Tablets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... August 01, 2015 , ... Have you ever wondered what “Karma” really means? Does ... the word “Karma.” , Vedic tradition, which gave birth to Hinduism, is one of ... the central concepts of this tradition. According to the wisdom of this heritage, Karma is ...
(Date:8/1/2015)... ... 2015 , ... Calvary Hospital today announced that it is embarking on a ... is to bring this Torah – dating from 1880 – back to kosher status, ... , Scroll No. 515, from the town of Taus-Domazlice, is on permanent loan ...
(Date:8/1/2015)... ... ... Brig and Lita Hart, icons of the network marketing industry and founders ... with the HOPE Movement of EvolvHealth. In what has been a long-term relationship between ... join their missions of purpose together to change the course of the network marketing ...
(Date:8/1/2015)... ... August 01, 2015 , ... On Tuesday, July 28th, Symantec ... are thought to have been behind the attack on Anthem Inc. which resulted in ... day exploits, watering hole attacks and spear phishing campaigns. , For Joe ...
(Date:8/1/2015)... ... 01, 2015 , ... BeverlyD, owner and founder of BeverlyD Luxe Organic Hair ... first small business donation to kick off the campaign for healing and Well-Being. , ... includes a complete line of raw, organic hair care products, as well as her ...
Breaking Medicine News(10 mins):Health News:Nithyananda Yoga Foundation to Conduct Global Webinar on Karma at No Charge on August 1st 2Health News:Calvary Hospital Announces Plans to Restore Historic Torah 2Health News:Calvary Hospital Announces Plans to Restore Historic Torah 3Health News:Looking for HOPE? Healthy Home Has Evolv’d 2Health News:Looking for HOPE? Healthy Home Has Evolv’d 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 2Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 4Health News:March4thforWellBeing Foundation Kickoff 2
... Telephone Contact in TreatmentCOLUMBIA, S.C., April 6 ... awarded Silver Honors for Health Plans and Health Networks ... . The honor was announced at the ... and Protection Awards Gala on April 1-2 ...
... achieves record success rates with a breakthrough hypnosis technique to quit ... ... CA (PRWEB) August 15, 2006 -- Franc Tausch, PhD, CCHT, of ... smoking for life by attending one personalized and individual hypnotherapy ...
... Calls on Americans to be Prepared to Offer Contributions, Goods, ... Left HomelessNEW YORK, April 6 The catastrophic earthquake in ... people dead and tens of thousands homeless is a subject ... Citizens Foundation in New York City. "Like all Americans, ...
... could delay orgasm six times longer than before , , ... men with premature ejaculation to delay their orgasm six times ... European men. , The men, with clinically diagnosed premature ejaculation, ... active ingredients (100 men) or the PSD502 spray, which contains ...
... D. Anderson Cancer Center have discovered a gene that protects ... in about half of all breast cancers. , The gene ... in several other types of cancer, the team reports in ... for diminished PTEN protein levels in breast cancer absent a ...
... first four in nation to receive accreditationGREEN BAY, ... Medical Center is one of the first four ... the National Accreditation Program for Breast Centers (NAPBC), ... the first breast program in Wisconsin to earn ...
Cached Medicine News:Health News:Companion Benefit Alternatives Awarded Silver Honors for Best Practices in Health Plans and Health Networks by URAC 2Health News:Companion Benefit Alternatives Awarded Silver Honors for Best Practices in Health Plans and Health Networks by URAC 3Health News:Hypnotherapy Breakthrough: Renowned Smoking Cessation Specialist Helps To Stop Smoking In One Session 2Health News:Topical Spray Helped Men With Premature Ejaculation 2Health News:Gene helps protect tumor suppressor in breast cancer 2Health News:Aurora BayCare is Wisconsin's First Nationally Accredited Breast Program 2
(Date:7/31/2015)... According to a new market research report " ... Oxide, Filtration, E-beam, Gamma), Services (Onsite & Offsite), Consumables (Indicators, ... to 2020", published by MarketsandMarkets, The Sterilization Equipment Market is ... a CAGR of 7.6%.from 2015 to 2020. ... ables and 37 F igures ...
(Date:7/31/2015)... PORTLAND, Ore., July 31, 2015  Semler Scientific, Inc. ... and testing services to healthcare insurers and physician groups, ... June 30, 2015. "In the second ... over year revenue growth of 54%, quarter over quarter ... of the installed base of FloChec® units of 18%," ...
(Date:7/31/2015)... Magnaquest, a leading Subscription ... cloud computing operators has signed a Proof of ... Internet of Things (IoT) related initiative. The PoC ... model.      (Logo: http://photos.prnewswire.com/prnh/20140807/700645 ) ... business innovations to make healthcare services more accessible ...
Breaking Medicine Technology:Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 2Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 3Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 4Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2
... CHADDS FORD, Pa., July 10 ... Pharmaceuticals (Nasdaq: ENDP ) jointly announced today that ... and market Urocidin(TM) in the U.S. with an option for ... Mycobacterial Cell Wall-DNA Complex (MCC) developed by Bioniche for the ...
... , ALEXANDRIA, Va., July 9 The world-wide explosion of ... of obesity is widely recognized. Could it really be an ... over the increasing prevalence of overweight conditions in our society, ... as a potential direct contributor to obesity. , ...
Cached Medicine Technology:Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM) 2Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM) 3Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM) 4Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM) 5Bioniche Life Sciences Inc. and Endo Pharmaceuticals Sign Licensing Agreement for Urocidin(TM) 6Is Obesity an Oral Bacterial Disease? 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: