Navigation Links
Promising new TB drug given special status by US and European regulators
Date:10/25/2007

What: Approximately one-third of the worlds population is infected with Mycobacterium tuberculosis, the bacterium that causes TB, and an estimated 1.6 million people died of the disease in 2005. Currently, TB patients must adhere to a complex treatment regimen over a six- to nine-month period. This demanding schedule often results in patients skipping treatment doses, which has given rise to drug-resistant strains of M. tuberculosis, including multi-drug-resistant (MDR) and, more recently, extensively drug-resistant (XDR) TB.

SQ109, an antimicrobial agent developed through a partnership between the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, and the biotech company Sequella, Inc., has recently been granted orphan drug status by the U.S. Food and Drug Administration and the European Medicines Agency for development against drug-susceptible and drug-resistant TB. This orphan designation will help accelerate clinical testing of the drug; SQ109 (in combination with other TB drugs) may help establish simpler and more effective treatment regimens for the disease.

Recent events have underscored the immense problem of antimicrobial resistance, including the growing threat of MDR-TB, according to NIAID Director Anthony S. Fauci, M.D. The advancement of SQ109 to a clinical candidate, he says, demonstrates the key role that public-private partnerships can play in developing new interventions to improve public health.

SQ109 was discovered by NIAID scientists in 1999 and developed with grant and contract support from NIAID and contributions by the National Cancer Institute/NIAID Inter-Institute Program for the Development of AIDS-related Therapeutics. NIAID licensed the SQ109 technology to Sequella in March 2006 under a Cooperative Research and Development Agreement.


'/>"/>

Contact: NIAID News and Public Information Branch
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Page: 1

Related medicine news :

1. PCR emerging as a promising technique for Diagnosing Urinary Tuberculosis
2. Experimental treatment for Ebola Virus Shows promising results in mice
3. Promising Treatment for Diabetes
4. A promising treatment for wart removal
5. Hepatitis shots is promising
6. Life after Bypass not so Promising for Women.
7. Promising cure for West Nile Virus
8. Deadly Diarrhoea Vaccine – Trail Results Promising
9. Novartis MS Drug Shows Promising Results
10. Sunitinib a Promising Agent for Treatment of Renal Cell Cancer
11. Research Ethics Requirements Compromising Quality of Health Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... Your brain structure could help predict how willing you are ... at Yale University found those with greater volume in a ... be more likely to engage in risky behavior than people ... funded by the U.S. National Institute on Aging, involved two ... Northeast. The researchers sought to determine how brain structure influences ...
(Date:9/19/2014)... 2014 The Alliance for Bangladesh ... the National Fire Protection Association (NFPA), a recognized ... today in a Memorandum of Understanding signed by ... and other stakeholders with information, guidance and access ... health and safety of workers in ready-made garment ...
(Date:9/19/2014)... IRVINE, CA (PRWEB) September 19, 2014 In ... has been an active part of the project’s social ... this movement, which aims to re-define the perception of beauty ... Beauty Project began as an idea by Shelly Baer and ... showed disabled women as sexy and beautiful. Ginny Dixon, Wendy ...
(Date:9/19/2014)... Famous Vancouver company, Pro Ace Heating and Mechanical ... a one-stop-solution for heating, air conditioning, plumbing and electrical ... has achieved this status by providing a complete package ... are many companies that provide these services separately, it ... can offer all of these services together to clients. ...
(Date:9/19/2014)... 2014) Shahram Majidi, M.D., a second-year resident ... Washington University School of Medicine and Health Sciences, ... Association to study the presence of diffuse brain ... (ICH). , "According to epidemiological studies, intracerebral hemorrhage ... strokes, but is the least treatable form of ...
Breaking Medicine News(10 mins):Health News:Brain Structure Might Help Predict Risky Behavior 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 3Health News:OC Healthcare Agency StudioPMG Partners with The Raw Beauty Project ™ NYC 2014 2Health News:Pro Ace Now Provides Heating, Air Conditioning, Plumbing & Electrical Services under One Roof 2Health News:GW researcher receives grant to study brain swelling following bleeding in the brain 2
... also available in <A HREF="http://www.eurekalert.org/pub_releases_ml/2008-08/aaft-t080108.php,">German . , , If ... might change, but they don,t immediately pull off one ... third leg. With some molecules, however, the situation is ... with seven atoms. In a charged state, the atoms ...
... a popular nutritional supplement renowned for enhancing athletic ... outcomes in patients with chronic obstructive pulmonary disease ... placebo-controlled, double-blind study provided the most powerful evidence ... supplementation was negligible at best among these patients. ...
... have had self-inflicted DIY disasters. More than half a million people have ... ... Cardiff, UK (PRWEB) August 1, 2008 -- Nearly six million (5,904,000) UK ... leading insurance price comparison site., , , , ,Research from Confused.com found ...
... year, Omega Institute will host an important conference at its Rhinebeck ... to explore the latest research and development in treating and living ... ... 2008 -- For the second consecutive year, Omega Institute will ...
... research shows that cannabinoid cell surface receptor CB1 plays ... in the Aug. 1 edition of the journal ... pain and nausea, elevating mood and stimulating appetite by ... of signaling molecules. It now may serve as a ...
... Senate, House Members Demonstrate Strong, Bipartisan Leadership in,Helping ... Medicare Funding for Care of,America,s Seniors, WASHINGTON, ... and the Alliance for Quality Nursing Home Care ... proposed Medicare,cuts, crediting a number of key Republican ...
Cached Medicine News:Health News:Nano sculptures in gold 2Health News:Nano sculptures in gold 3Health News:Nano sculptures in gold 4Health News:No substitute for hard work: Creatine supplementation does not improve exercise outcomes in COPD 2Health News:DIY Disasters Cost the Average Brit 669.58, Says Confused.com* 2Health News:DIY Disasters Cost the Average Brit 669.58, Says Confused.com* 3Health News:Omega to Hold Conference: Autism Through the Life Span II 2Health News:Omega to Hold Conference: Autism Through the Life Span II 3Health News:Turned-off cannabinoid receptor turns on colorectal tumor growth 2Health News:Turned-off cannabinoid receptor turns on colorectal tumor growth 3Health News:AHCA-Alliance Praise Bush Administration for Reversing Planned Medicare Cuts, Protecting Seniors 2
(Date:9/19/2014)... CHICAGO , Sept. 19, 2014  4WEB Medical ... of 3D-printed foot and ankle osteotomy implants on ... and Ankle Society annual meeting in Chicago ... for all of a surgeon,s osteotomy needs with 74 size ... wedge systems had smaller offerings of only 15 to 18 ...
(Date:9/19/2014)... , Sept. 19, 2014 Merck (NYSE: MRK ... and Canada , is teaming with celebrity ... Diabetes: Logra Tus Metas , an educational program encouraging Hispanics with ... -- a key treatment goal to help reduce the risk of ... are at a higher risk for developing type 2 diabetes ...
(Date:9/19/2014)... 2014  Diplomat, the nation,s largest independent specialty pharmacy, ... to the Board of Directors on September 15, 2014. ... serve as chair of the Audit Committee. ... financial, compliance and operating experience in the health care ... chief financial officer, chief operating officer and secretary of ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5David Dreyer Appointed to Diplomat Board of Directors 2
TC-98 elisa strip reader. Reads, calculates, and prints results for up to 12 wells in about 30 seconds. Single point calibration. Multi-point calibration....
Lab-Incubator/Shaker....
... designed to give reliable performance for all mixing ... button, power supply socket and fuse holder are ... The speed knob is located on the bottom ... a minimum 950 rpm to a maximum of ...
Microplate incubator shaker used in a variety of immunoassay and research procedures requiring microplates....
Medicine Products: