Navigation Links
Promising advances in islet cell transplants for diabetes
Date:6/9/2008

University of Illinois at Chicago researchers have modified the procedure for islet cell transplantation and achieved insulin independence in diabetes patients with fewer but better-functioning pancreatic islet cells.

The study results are published in the June issue of the American Journal of Transplantation.

UIC is one of only a few centers worldwide able to achieve reproducible and consistent insulin independence in severe type 1 diabetes patients.

In the UIC study, 10 patients with diabetes received between one and three islet cell transplants and were followed for 15 months.

Four received the Edmonton protocol, developed at the University of Alberta, which uses a combination of two immunosuppressants and a monoclonal antibody drug, daclizumab.

Six patients received the UIC protocol -- a combination of etanercept (an anti-inflammatory drug developed to treat rheumatoid arthritis) and exenatide (a drug approved for use in type 2 diabetes to improve glucose control) -- and the Edmonton regimen.

The new procedure allowed patients to get off insulin after a single transplant versus the two to four transplants that were needed using the older protocol, said Dr. Jos Oberholzer, director of cell and pancreas transplantation at UIC and lead author of the study.

All patients in the study achieved insulin independence, but those who received the UIC protocol required fewer than half the number of islets as those who were treated under the Edmonton protocol.

The four patients who received the Edmonton protocol needed either two or three sequential islet cell transplants to achieve insulin-independence.

The six patients who were treated using the UIC protocol initially achieved insulin-independence after only one islet transplant. Two of these patients required a second islet cell transplant, and one resumed insulin five months after the second transplant due to other complication
'/>"/>

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Promising drug combination may help those with ocular melanoma that has spread
2. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
3. Molecule Promising Against Huntingtons Disease
4. Computerized training of working memory is a promising therapeutic strategy in ADHD
5. Baicalin might be a promising therapeutic tool for severe acute pancreatitis
6. Initial Evaluation of New Nucleus Removal Device Provides Promising Results
7. Promising new TB drug given special status by US and European regulators
8. New Drug Promising Against Tough-to-Treat Kidney Cancer
9. Einstein scientists treat cancer as an infectious disease -- with promising results
10. Thomson Scientific Publishes its Third Quarter Issue of the Ones to Watch Reviewing the Most Promising Drugs in the Pharmaceutical Pipeline
11. Protalix BioTherapeutics prGCD Named One of the Five Most Promising Drugs Entering Phase III Trials by Thomson Scientific
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2015)... As one of only 30 Illinois companies to ... Achievement and Recognition Program (SHARP) certification, Essentra Specialty ... Illinois Department of Labor to host this special event. ... by the Occupational Safety and Health Administration’s (“OSHA”) Onsite ... meet or exceed all of the necessary regulations and ...
(Date:5/2/2015)... ProText Kinetic 2 is a set of ... Pro X. ProText Kinetic 2 features 40 animation ... Pro X . Easily create interactive text videos without ... ProText Kinetic 2. , Using ProText Kinetic is as easy ... Kinetic presets in the FCPX timeline. Playback the default ...
(Date:5/2/2015)... 2015 On Tuesday April 7th, the ... gathered to celebrate improvements in patient care. In 2014 ... (RVHP), had zero acquired ventilator associated infections, zero central ... ELCH was also recently named a Top Performer by ... ELCH credited the teamwork of staff from all departments ...
(Date:5/2/2015)... success that Veatch Dental Consulting has had over the years, ... Shields to the team. With Neida and Alex on board, ... working with dentists to ensure their success. , Neida Miranda ... She was certified as dental assistant from Texas State Technical ... the importance of oral hygiene to patients, Neida was moved ...
(Date:5/1/2015)... May 01, 2015 Jusuru International has ... the successful repositioning of its flagship nutritional supplement, Liquid ... with a new name, new logo, new packaging, new ... Awards are designed to identify and promote programs that ... , “DSA congratulates Jusuru International for their outstanding ...
Breaking Medicine News(10 mins):Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:Veatch Dental Consulting Services Welcomes New Team Members 2Health News:Jusuru International Receives 2015 DSA Ethos Award 2Health News:Jusuru International Receives 2015 DSA Ethos Award 3Health News:Jusuru International Receives 2015 DSA Ethos Award 4Health News:Jusuru International Receives 2015 DSA Ethos Award 5
... has received a $76 million grant from the Bill & ... young child nutrition in developing countries in Africa and Asia. ... increase rates of exclusive breastfeeding and improve complementary feeding for ... die and millions more are permanently disabled as a result ...
... Association of Community Bankers encourage you to report for Spring ... Derby EPHRATA, Pa., March 5 Batter Up! It,s time ... the ballpark! The Pennsylvania Breast Cancer Coalition (PBCC) and the ... to bring a Home Run Derby event to each of ...
... say, , , THURSDAY, March 5 (HealthDay News) -- If you,re ... handle that third glass of wine as well as you ... , Older adults who are social drinkers can become impaired ... realize it, University of Kentucky researchers report. , Most ...
... New Rochelle, NY, March 5, 2009Serious flaws in a ... C reduce the effectiveness of chemotherapeutic drugs in the ... of Alternative and Complementary Therapies , a journal ... This report is available free online at ...
... LLC Revolutionizes the Future of Bruise TreatmentMANDEVILLE, La., March ... announce the launch of Bruise Relief(TM), a topical skin ... at CVS stores and other fine drug retailers nationwide.Bruise ... and is designed to super-hydrate the skin to help ...
... 5 Phoenix Health Systems, a national provider ... process solutions, announced today its Total Security Program ... healthcare organizations a comprehensive suite of security services ... the organization,s security operations. The Program goes ...
Cached Medicine News:Health News:AED Receives Gates Foundation Grant to Improve Nutrition and Reduce Deaths Among Young Children in Developing Countries 2Health News:Take A Swing Against Breast Cancer! 2Health News:Older Adults Get Drunk Faster Than Younger Drinkers 2Health News:Older Adults Get Drunk Faster Than Younger Drinkers 3Health News:Support for adjunctive vitamin C treatment in cancer 2Health News:Say Goodbye to Unsightly Bruises and Skin Discolorations with Bruise Relief(TM) 2Health News:Phoenix Health Systems Launches Total Security Program for the Healthcare Industry 2
(Date:5/1/2015)... Calif., May 1, 2015 Pharmacyclics, Inc. (the ... for the quarter ended March 31, 2015, as well ... AbbVie Inc., no conference call will be held. ... quarter ended March 31, 2015 increased to $206 million ... 2014. , Worldwide IMBRUVICA ® (ibrutinib) net ...
(Date:5/1/2015)... -- Semler Scientific, Inc. (Nasdaq: SMLR ), an ... markets products that assist healthcare providers in monitoring patients ... the first quarter ended March 31, 2015. ... continued progress with year over year growth of 44% ... said Doug Murphy-Chutorian , M.D., chief executive officer ...
(Date:5/1/2015)... May 1, 2015  AcelRx Pharmaceuticals, Inc. (Nasdaq: ACRX ... and commercialization of innovative therapies for the treatment of ... E. Morris , chief financial officer  will be participating ... are as follows: Mizuho Third Annual Healthcare ... Omni Berkshire Place, New York ...
Breaking Medicine Technology:Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 2Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 3Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 4Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 5Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 6Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 7Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 8Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 9Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 10Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 11Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 12Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 13Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 14Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 15Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 16Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 17Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 18Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 19Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 20Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 21Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 22Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 23Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 24Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 25Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 26Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 27Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 28Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 29Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 30Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 31Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 32Pharmacyclics Reports First Quarter 2015 Financial Results and Provides Business Updates 33Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4
... 21, 2012 As communities in the United States gather ... Pharma, LLC,s SyNAPSe® clinical trial reaches an important enrollment milestone. ... in March to raise awareness for the need for better ... than 75 clinical trials in the past 20 years, no ...
... Faruqi, LLP, a leading national securities law firm, ... Inc. ("ZELTIQ" or the "Company") (NASDAQ: ZLTQ).    ... Faruqi & Faruqi is investigating allegations that ZELTIQ ... information about the delayed sale of Company products ...
Cached Medicine Technology:BHR Pharma's SyNAPSe® Trial Reaches Important Enrollment Milestone on Brain Injury Awareness Day 2BHR Pharma's SyNAPSe® Trial Reaches Important Enrollment Milestone on Brain Injury Awareness Day 3Faruqi & Faruqi, LLP Announces Investigation of ZELTIQ Aesthetics, Inc. 2
... two groups of flexible lighting products. The ... in three different sizes 5", 10", and ... of the light). These lights are for ... needed., ,The second group of flexible ...
... toggle switches at off (center position) , Double Burst ... .75 s; repeats every 10 s , Twitch: 1 ... 50 Hz (50 pulses/s) or 100 Hz (100 pulses/s) ... s; repeats every 10 s) , Output Current: Adjustable ...
... Modes of Operation: , Standby: All toggle switches ... s (1 pulse/s); 10 s (1 pulses/10 s) ... Hz (100 pulses/s) , Train-Of-Four: Single (4 pulses/2 ... s) , Output Current: Adjustable from 0-70 mA(HI ...
... Modes of Operation: , Double Burst : 2 ... , Twitch: 1 s (1 pulse/s) , Tetanus: ... , Train-Of-Four: Single (4 pulses/2 s) , Output ... Square Wave Monophasic pulses (200-us duration) , Indicators: Battery ...
Medicine Products: