Navigation Links
Promising advances in islet cell transplants for diabetes
Date:6/9/2008

University of Illinois at Chicago researchers have modified the procedure for islet cell transplantation and achieved insulin independence in diabetes patients with fewer but better-functioning pancreatic islet cells.

The study results are published in the June issue of the American Journal of Transplantation.

UIC is one of only a few centers worldwide able to achieve reproducible and consistent insulin independence in severe type 1 diabetes patients.

In the UIC study, 10 patients with diabetes received between one and three islet cell transplants and were followed for 15 months.

Four received the Edmonton protocol, developed at the University of Alberta, which uses a combination of two immunosuppressants and a monoclonal antibody drug, daclizumab.

Six patients received the UIC protocol -- a combination of etanercept (an anti-inflammatory drug developed to treat rheumatoid arthritis) and exenatide (a drug approved for use in type 2 diabetes to improve glucose control) -- and the Edmonton regimen.

The new procedure allowed patients to get off insulin after a single transplant versus the two to four transplants that were needed using the older protocol, said Dr. Jos Oberholzer, director of cell and pancreas transplantation at UIC and lead author of the study.

All patients in the study achieved insulin independence, but those who received the UIC protocol required fewer than half the number of islets as those who were treated under the Edmonton protocol.

The four patients who received the Edmonton protocol needed either two or three sequential islet cell transplants to achieve insulin-independence.

The six patients who were treated using the UIC protocol initially achieved insulin-independence after only one islet transplant. Two of these patients required a second islet cell transplant, and one resumed insulin five months after the second transplant due to other complication
'/>"/>

Contact: Sherri McGinnis Gonzalez
smcginn@uic.edu
312-996-8277
University of Illinois at Chicago
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Promising drug combination may help those with ocular melanoma that has spread
2. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
3. Molecule Promising Against Huntingtons Disease
4. Computerized training of working memory is a promising therapeutic strategy in ADHD
5. Baicalin might be a promising therapeutic tool for severe acute pancreatitis
6. Initial Evaluation of New Nucleus Removal Device Provides Promising Results
7. Promising new TB drug given special status by US and European regulators
8. New Drug Promising Against Tough-to-Treat Kidney Cancer
9. Einstein scientists treat cancer as an infectious disease -- with promising results
10. Thomson Scientific Publishes its Third Quarter Issue of the Ones to Watch Reviewing the Most Promising Drugs in the Pharmaceutical Pipeline
11. Protalix BioTherapeutics prGCD Named One of the Five Most Promising Drugs Entering Phase III Trials by Thomson Scientific
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... the clinical indicators most strongly associated with concussion is ... evidence-based guidelines for concussion diagnosis, prognosis, and treatment, according ... , official journal of the Congress ... Lippincott Williams & Wilkins , a part of ... on analysis of the best available research data, a ...
(Date:7/10/2014)... just as tempting as full-fat equivalents could be ... into how proteins can replace fats without affecting ... the Engineering and Physical Sciences Research Council (EPSRC), ... of Edinburgh has produced modified proteins that easily ... the behaviour of fats during food manufacture. The ...
(Date:7/9/2014)... that sudden, acute episodes of low back pain are ... air pressure, wind direction and precipitation. Findings published in ... the American College of Rheumatology (ACR), indicate that the ... wind speed or wind gusts, but was not clinically ... (WHO) nearly everyone experiences low back pain at some ...
(Date:7/9/2014)... in almost all types of cancer sends the protein ... fuel a tumour,s uncontrolled growth, new research suggests. , ... a molecular trigger responsible for ratcheting up activity of ... makes the building blocks cancer cells need to keep ... called SREBP, controls the flow of messages to the ...
(Date:7/9/2014)... found that fecal transplantation is effective and safe for ... is the result of a study led by Colleen ... Gastrointestinal Medicine at The Women,s Medicine Collaborative. The study ... of print in the American Journal of Gastroenterology ... diff , has increased to epidemic proportions over the ...
Breaking Medicine News(10 mins):Health News:What's a concussion? Review identifies four evidence-based indicators 2Health News:What's a concussion? Review identifies four evidence-based indicators 3Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2Health News:Low back pain? Don't blame the weather 2Health News:Signal may send cancer's cellular factories into overdrive 2Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2
... confirms that impotence is a risk factor for heart ... suffering from both cardiovascular disease and erectile dysfunction are ... and death, a new study finds. , Moreover, treatments ... so the German researchers concluded that erectile dysfunction is ...
... ... between the corporate and academic worlds in the medical device industry. , ... (PRWEB) March 15, 2010 -- The First Annual ... Hosted by the Biomedical Engineering Society @ San Jose State University, this event will take ...
... ... at Children,s Memorial Hospital may be able to identify infants at high risk ... 48 hours after birth. The medical device making this possible is called the Pea ... fast, non-invasive mechanism to measure newborn body fat. , ...
... Reno , Salt Lake City , and Denver in May are set to help employers improve hearing conservation efforts and prevent noise-induced hearing loss among their workers. , ... , ... ... ...
... The Greater San Antonio Chamber of Commerce and ... at a luncheon on March 31st who have made ... part of the 2010 Women,s Opportunity Week (WOW), Ford Motor Company ... McClendon ( Texas State Representative, District 120 ), ...
... NEW YORK , March 15 Expectant mothers ... pregnancy experience thanks to the new Prenatal Yoga for Partners ... organic baby and toddler food company. One of the only products ... and founder Shazi Visram and her husband, Joe ...
Cached Medicine News:Health News:Erectile Dysfunction Plus Heart Disease Raises Death Risk 2Health News:Erectile Dysfunction Plus Heart Disease Raises Death Risk 3Health News:First Annual Bay Area Biomedical Device Conference to be Held at San Jose State University 2Health News:First Annual Bay Area Biomedical Device Conference to be Held at San Jose State University 3Health News:Study to Identify Infants at High Risk for Developing Obesity 2Health News:Study to Identify Infants at High Risk for Developing Obesity 3Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 2Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 3Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 4Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 5Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 6Health News:Free Seminars to Help Employers Prevent Noise-Induced Hearing Loss Among Workers Set for Phoenix, Reno, Salt Lake City, Denver in May 7Health News:San Antonio Chamber Honors Women Business, Community Leaders 2Health News:San Antonio Chamber Honors Women Business, Community Leaders 3Health News:San Antonio Chamber Honors Women Business, Community Leaders 4Health News:HAPPYBABY Unveils Partners Prenatal Instructional Yoga DVD 2Health News:HAPPYBABY Unveils Partners Prenatal Instructional Yoga DVD 3Health News:HAPPYBABY Unveils Partners Prenatal Instructional Yoga DVD 4
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Insulin Pump ... http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining strong acceptance ...
(Date:1/15/2014)... CAMBRIDGE, Mass. , Jan. 15, 2014  Zafgen, ... the unmet needs of severely obese patients, today ... of beloranib, a selective inhibitor of methionine aminopeptidase ... a severe form of genetic obesity.  These results ...
(Date:1/14/2014)... , Jan. 14, 2014 The Brandeis Medical Center, led ... a premier and affordable laser tattoo removal experience with ... Brandeis, focus is in providing high quality cosmetic services with cutting ... " Southern California has seen a ...
Breaking Medicine Technology:Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... 7, 2011 EntreMed, Inc. (Nasdaq: ENMD ... treatment of cancer, today announced that Selected Value Therapeutics ... an exclusive license to develop and commercialize EntreMed,s Phase ... of its territories.  EntreMed retains development and commercialization rights ...
... June 7, 2011 Topaz Pharmaceuticals Inc., a privately ... Food and Drug Administration (FDA) accepted for filing the ... topical cream as a treatment for head lice infestations ... represents the transition of the Company from the development ...
Cached Medicine Technology:Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 2Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 3Selected Value Therapeutics Exercises Right to Develop and Commercialize ENMD-2076 in China 4Topaz Pharmaceuticals Announces New Drug Application for the Treatment of Head Lice Accepted by FDA 2Topaz Pharmaceuticals Announces New Drug Application for the Treatment of Head Lice Accepted by FDA 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: