Navigation Links
Promising Therapy for Prostate Cancer
Date:6/22/2009

Experimental drug beat back inoperable cancer in two patients, study claims

MONDAY, June 22 (HealthDay News) -- An experimental drug therapy appears to have helped destroy allegedly inoperable prostate cancer in two patients in a clinical trial.

Use of the immunotherapeutic agent MDX-010, or ipilimumab, in combination with standard hormone and radiation treatments helped eliminate the aggressive tumors, which had already spread into the patients' abdominal areas, according to a report from Mayo Clinic researchers that appears in Discovery's Edge, the Mayo Clinic's online research magazine. Both patients are now considered cancer-free.

"The tumors had shrunk dramatically," co-investigator Dr. Michael Blute, a Mayo urologist and surgeon who operated on both patients, said in a Mayo Clinic news release. "I had never seen anything like this before. I had a hard time finding the cancer. At one point, the pathologist [who was working during surgery] asked if we were sending him samples from the same patient."

Ipilimumab is an antibody that appears to greatly magnify the cancer-killing action of androgen ablation, a hormone therapy that helps shrink prostate cancer by eliminating testosterone from the body. Following the additional treatment, the patients showed steady decreases in their prostate-specific antigen (PSA) counts, a test used to detect prostate cancer, and were deemed eligible for surgery. After surgery, one patient underwent additional radiation therapy.

"This is one of the Holy Grails of prostate cancer research," clinical trial leader Dr. Eugene Kwon, a Mayo Clinic urologist, said of the antibody therapy in the same news release.

The team plans more research into how ipilimumab works and how to optimize its use.

More information

The American Cancer Society has more about prostate cancer.



-- Kevin McKeever



SOURCE: Mayo Clinic, news release, June 19, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Promising drug combination may help those with ocular melanoma that has spread
2. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
3. Molecule Promising Against Huntingtons Disease
4. Computerized training of working memory is a promising therapeutic strategy in ADHD
5. Baicalin might be a promising therapeutic tool for severe acute pancreatitis
6. Initial Evaluation of New Nucleus Removal Device Provides Promising Results
7. Promising new TB drug given special status by US and European regulators
8. New Drug Promising Against Tough-to-Treat Kidney Cancer
9. Einstein scientists treat cancer as an infectious disease -- with promising results
10. Thomson Scientific Publishes its Third Quarter Issue of the Ones to Watch Reviewing the Most Promising Drugs in the Pharmaceutical Pipeline
11. Protalix BioTherapeutics prGCD Named One of the Five Most Promising Drugs Entering Phase III Trials by Thomson Scientific
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Promising Therapy for Prostate Cancer
(Date:2/12/2016)... ... 2016 , ... The law firm of Morrow, Morrow, Ryan & Bassett is ... these scholarships is to encourage applicants to pursue a degree in their field of ... parishes. , “We have available jobs in St. Landry and Evangeline Parishes that ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... — 1:30 p.m. – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination ... cycle of pharmaceutical products, garnering increased attention from all stakeholders in the development ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... announced that nominations have closed for the ISE Southeast Awards 2016. Finalists and ... announced at the ISE® Southeast Executive Forum and Awards Gala on March 15, ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fisher House Foundation Chairman and CEO Kenneth Fisher ... Military Support Alliance president Scott Bensing, and Peggy Kearns Director, VA Southern Nevada Healthcare ... System. This will be the first Fisher House in Nevada, and will provide ...
(Date:2/12/2016)... ... February 12, 2016 , ... Erlanger Agency has announced a new partnership in ... latest campaign focuses on the fight against breast cancer, fundraising for a local woman ... here . , Carmen is a loving single mother of two boys who also ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Stem cells are primitive cells found in all multi-cellular ... to differentiate into mature cell types Stem cells are ... embryonic stem cells were derived from embryos in 1981, ... culturing of embryonic stem cells from non-human primates occurred ... As a result of these discoveries, stem cells can ...
(Date:2/11/2016)... 2016  Kindred Biosciences, Inc. (NASDAQ: KIN ), ... lives of pets, today announced the submission to FDA ... Drug Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive ... Zimeta for the control of pyrexia (fever) in horses ... --> --> The Chemistry, Manufacturing, and ...
(Date:2/11/2016)...   Health 2.0 , the premiere showcase and ... today " 10 Year Global Retrospective ", a platform ... past ten years.   --> ... has served as the preeminent thought-leader in the health ... technologies, companies, innovators, and patient-activists through an array of ...
Breaking Medicine Technology: