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Prometheus Announces Co-Pay Assistance Savings Program for LOTRONEX(R) (alosteron HCl) Tablets
Date:9/9/2009

mented to help reduce risks of serious gastrointestinal adverse events. Information about the Prescribing Program for Lotronex is available by calling 888.423.5227 or visiting www.Lotronex.com. Please see the accompanying complete prescribing information, including Boxed Warning, for LOTRONEX at www.Lotronex.com/PDF/us_lotronex.pdf.

About IBS

According to the National Institute of Diabetes and Digestive and Kidney Diseases, in 2007, almost 60 million, or 20%, of the U.S. population had symptoms of IBS, making it one of the most common disorders diagnosed by physicians. At least twice as many women as men are affected by IBS, of which more than 35% have IBS-D.(3,4) IBS is characterized most commonly by cramping, abdominal pain, bloating, constipation and diarrhea. Although it significantly impairs health-related quality of life, many people suffer from IBS for years before being properly diagnosed and treated.

About Prometheus

Prometheus Laboratories Inc. is a specialty pharmaceutical and diagnostic company committed to developing and commercializing novel pharmaceutical and diagnostic products to help physicians individualize patient care. Prometheus is a leader in applying the principles of personalized medicine to the diagnosis and treatment of gastrointestinal diseases and intends to apply these principles to oncology. Its strategy includes the marketing and delivery of pharmaceutical products complemented by proprietary, high-value diagnostic testing services. By integrating pharmaceutical products and diagnostic testing services, Prometheus believes it can address the full continuum of care, thereby providing physicians with a comprehensive solution to treat chronic diseases. Prometheus' corporate offices are located
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