Navigation Links
Progesterone Won't Shield Women Against Alzheimer's
Date:11/29/2007

Mouse study shows no benefit for the female hormone

THURSDAY, Nov. 29 (HealthDay News) -- There's no evidence that progesterone -- which is often given with estrogen in hormone replacement therapy -- offers women any protection against Alzheimer's disease, U.S. researchers say.

They conducted tests on female mice genetically engineered to develop an Alzheimer's-like disease to come to this conclusion.

Treatment with estrogen blocked the Alzheimer's-like symptoms in the mice, while treatment with progesterone did not. In fact, when the mice were given both hormones, progesterone appeared to block estrogen's main benefit -- preventing the buildup of beta amyloid protein in the brain, a key factor in Alzheimer's.

The researchers, led by gerontologist Christian Pike of the University of Southern California, did find that progesterone seemed to inhibit tau hyperphosphorylation, another chemical process implicated in Alzheimer's.

The study appears in this week's issue of the Journal of Neuroscience.

Previous research suggested that estrogen offers women some protection against Alzheimer's disease. The authors of this new study wanted to determine if the same might be true of progesterone.

The findings may provide guidance for the design of human trials examining hormone therapy and Alzheimer's, Pike said. Future studies may need to focus on both the dosage and formulations of progestins (synthetic versions of progesterone given to humans), as well as the starting age for hormone therapy, he noted.

More information

The U.S. National Institute on Aging discusses whether Alzheimer's can be prevented.



-- Robert Preidt



SOURCE: University of Southern California, news release, Nov. 27, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Vaginal progesterone gel may improve infant outcomes and...
2. Alvarado Hospital Files Countersuit Against Blue Shield
3. BlueCare(R) Family Plan, a HUSKY Health Plan from Anthem Blue Cross and Blue Shield in Connecticut, Raises Awareness, Funds and Diapers for New Haven Diaper Bank
4. Blue Cross Blue Shield of Michigan Corrects News Story about Drug Coverage Announcement
5. Karen Vigil Named Senior Vice President and Chief Executive Officer, Blue Shield of Californias Individual, Small Group, and Government Business Unit
6. Highmark Blue Cross Blue Shield Introduces New Health Plan Comparison Tool for Consumers
7. Highmark Blue Shield Introduces New Health Plan Comparison Tool for Consumers
8. Blue Cross and Blue Shield Initiatives Recognized for Increasing Patient Safety and Efficiency
9. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
10. Blue Cross Blue Shield of Michigan Offers New Approach to Customer Group Wellness
11. Blue Cross and Blue Shield Association Holds Forum to Explore Patient Safety and Healthcare Quality Initiatives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... , ... May 24, 2017 , ... ... implants in Bayside, NY, who have now spent 10 years as clinical instructors ... York University (NYU) College of Dentistry. Through the program, private practitioners receive cutting-edge ...
(Date:5/24/2017)... NV (PRWEB) , ... May 24, 2017 , ... ... NV, recently completed Course II of the HP3 (High-Performance Periodontal Practice) continuing education ... to learning the latest advancements in his field by attending numerous CE courses ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... offering holistic pediatric dentistry options for its patients on Long Island, New York. ... entire physical well being, and is one of the biggest trends in dentistry ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... sleep diagnostics sensors, announced today it had completed the first phase of building ... of domestic and rest of world (ROW) authorized dealers specializing in polysomnography accessories. ...
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... ... in North Carolina have remained steady since 2009, according to a Workers Compensation ... , The study Monitoring the North Carolina System: CompScope™ Benchmarks, 17th Edition ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... 2017 Global Health Intelligence (GHI), the ... , published its 2017 ranking of the Best-Equipped ... extensive data analysis from GHI,s hospitals database for Latin ... the region. The GHI database covers 86% of the hospitals ... 130 data points for each institution in key areas such ...
(Date:5/10/2017)... Ill. , May 10, 2017 Radiology ... today; unfortunately its costs have also spiraled to the ... being sent to radiology than ever before as the ... diagnosis.  For a patient with lower back pain an ... no anatomical reason for pain, resulting in entirely different ...
(Date:5/9/2017)... Ind. , May 9, 2017 Zimmer ... leader in musculoskeletal healthcare, today announced it has earned ... Employers of 2017" list. The Company was ranked among ... of Large Employers and Healthcare Equipment and Services. ... employers based on an anonymous, independent survey of over ...
Breaking Medicine Technology: