Navigation Links
Progesterone Won't Shield Women Against Alzheimer's
Date:11/29/2007

Mouse study shows no benefit for the female hormone

THURSDAY, Nov. 29 (HealthDay News) -- There's no evidence that progesterone -- which is often given with estrogen in hormone replacement therapy -- offers women any protection against Alzheimer's disease, U.S. researchers say.

They conducted tests on female mice genetically engineered to develop an Alzheimer's-like disease to come to this conclusion.

Treatment with estrogen blocked the Alzheimer's-like symptoms in the mice, while treatment with progesterone did not. In fact, when the mice were given both hormones, progesterone appeared to block estrogen's main benefit -- preventing the buildup of beta amyloid protein in the brain, a key factor in Alzheimer's.

The researchers, led by gerontologist Christian Pike of the University of Southern California, did find that progesterone seemed to inhibit tau hyperphosphorylation, another chemical process implicated in Alzheimer's.

The study appears in this week's issue of the Journal of Neuroscience.

Previous research suggested that estrogen offers women some protection against Alzheimer's disease. The authors of this new study wanted to determine if the same might be true of progesterone.

The findings may provide guidance for the design of human trials examining hormone therapy and Alzheimer's, Pike said. Future studies may need to focus on both the dosage and formulations of progestins (synthetic versions of progesterone given to humans), as well as the starting age for hormone therapy, he noted.

More information

The U.S. National Institute on Aging discusses whether Alzheimer's can be prevented.



-- Robert Preidt



SOURCE: University of Southern California, news release, Nov. 27, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Vaginal progesterone gel may improve infant outcomes and...
2. Alvarado Hospital Files Countersuit Against Blue Shield
3. BlueCare(R) Family Plan, a HUSKY Health Plan from Anthem Blue Cross and Blue Shield in Connecticut, Raises Awareness, Funds and Diapers for New Haven Diaper Bank
4. Blue Cross Blue Shield of Michigan Corrects News Story about Drug Coverage Announcement
5. Karen Vigil Named Senior Vice President and Chief Executive Officer, Blue Shield of Californias Individual, Small Group, and Government Business Unit
6. Highmark Blue Cross Blue Shield Introduces New Health Plan Comparison Tool for Consumers
7. Highmark Blue Shield Introduces New Health Plan Comparison Tool for Consumers
8. Blue Cross and Blue Shield Initiatives Recognized for Increasing Patient Safety and Efficiency
9. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
10. Blue Cross Blue Shield of Michigan Offers New Approach to Customer Group Wellness
11. Blue Cross and Blue Shield Association Holds Forum to Explore Patient Safety and Healthcare Quality Initiatives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... 2016 , ... On Dec. 2, 2016, CURE® magazine will host the 4th ... 2016 MPN Heroes—eight individuals who have made a difference in the field of rare ... of care, demonstrating leadership within the MPN community and/or a commitment to individual patients. ...
(Date:12/2/2016)... ... , ... Advanced Inc., a leading provider of travel therapy and travel nursing ... as Advanced Inc.’s Chief Financial Officer, effective December 1, 2016. Jason previously served as ... operational leadership experience to Advanced Inc. He began his career in finance at Ernst ...
(Date:12/2/2016)... ... December 02, 2016 , ... The annual time frame to change ... Election Period), is ending December 7th. Currently-enrolled Medicare beneficiaries who are looking to switch ... plan (Part D) need to make changes during this period order for their new ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet’s newest campaign, ... standing as living proof that attitude and determination can combine into the most ... spike around the holidays. This campaign will offer patients a new-found hope, by ...
(Date:12/2/2016)... ... 2016 , ... Mediaplanet is proud to announce the launch ... innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping patients and physicians ... years in the last 3 decades,” says Dr. Valentine Fuster, a world-renowned cardiologist. ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... held the largest share in the ECG Cables And ... demand for remote monitoring ECG devices. On the other hand, ... to witness the highest growth rate during the forecast period. ... Dickinson and Company (U.S.), Medtronic plc ( Ireland ... and Mindray Medical International Limited ( China ), ...
(Date:12/2/2016)... , Dec 2, 2016 Research and Markets ... Share, Development, Growth and Demand Forecast to 2022" report to their ... , , ... $6 billion in 2015, and it is expected to grow at a ... is expected to witness faster growth during the forecast period, a CAGR ...
(Date:12/2/2016)... SAN FRANCISCO , Dec. 2, 2016  PipelineRx, ... clinical telepharmacy, will be offering demonstrations of its ... American Society of Health-System Pharmacists 2016 Midyear Clinical ... Las Vegas . With nearly 300 hospital ... telepharmacy services and technology designed to dramatically improve ...
Breaking Medicine Technology: