Navigation Links
Progesterone Won't Shield Women Against Alzheimer's
Date:11/29/2007

Mouse study shows no benefit for the female hormone

THURSDAY, Nov. 29 (HealthDay News) -- There's no evidence that progesterone -- which is often given with estrogen in hormone replacement therapy -- offers women any protection against Alzheimer's disease, U.S. researchers say.

They conducted tests on female mice genetically engineered to develop an Alzheimer's-like disease to come to this conclusion.

Treatment with estrogen blocked the Alzheimer's-like symptoms in the mice, while treatment with progesterone did not. In fact, when the mice were given both hormones, progesterone appeared to block estrogen's main benefit -- preventing the buildup of beta amyloid protein in the brain, a key factor in Alzheimer's.

The researchers, led by gerontologist Christian Pike of the University of Southern California, did find that progesterone seemed to inhibit tau hyperphosphorylation, another chemical process implicated in Alzheimer's.

The study appears in this week's issue of the Journal of Neuroscience.

Previous research suggested that estrogen offers women some protection against Alzheimer's disease. The authors of this new study wanted to determine if the same might be true of progesterone.

The findings may provide guidance for the design of human trials examining hormone therapy and Alzheimer's, Pike said. Future studies may need to focus on both the dosage and formulations of progestins (synthetic versions of progesterone given to humans), as well as the starting age for hormone therapy, he noted.

More information

The U.S. National Institute on Aging discusses whether Alzheimer's can be prevented.



-- Robert Preidt



SOURCE: University of Southern California, news release, Nov. 27, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Vaginal progesterone gel may improve infant outcomes and...
2. Alvarado Hospital Files Countersuit Against Blue Shield
3. BlueCare(R) Family Plan, a HUSKY Health Plan from Anthem Blue Cross and Blue Shield in Connecticut, Raises Awareness, Funds and Diapers for New Haven Diaper Bank
4. Blue Cross Blue Shield of Michigan Corrects News Story about Drug Coverage Announcement
5. Karen Vigil Named Senior Vice President and Chief Executive Officer, Blue Shield of Californias Individual, Small Group, and Government Business Unit
6. Highmark Blue Cross Blue Shield Introduces New Health Plan Comparison Tool for Consumers
7. Highmark Blue Shield Introduces New Health Plan Comparison Tool for Consumers
8. Blue Cross and Blue Shield Initiatives Recognized for Increasing Patient Safety and Efficiency
9. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
10. Blue Cross Blue Shield of Michigan Offers New Approach to Customer Group Wellness
11. Blue Cross and Blue Shield Association Holds Forum to Explore Patient Safety and Healthcare Quality Initiatives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... ... , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, Texas, has ... solve problems and pleads with world leaders to be more open about positive changes. Yisrayl ... He says there is a peaceful and positive way to solve all; yes, all issues, ...
(Date:7/21/2017)... ... 21, 2017 , ... “Kids aren't born knowing how to regulate their emotions ... Tucker, Founder of St. Louis-based positive education company Generation Mindful. To help with that ... July 21st. , The kit uses colorful, engaging and educational illustrations and games ...
(Date:7/21/2017)... TORONTO, ONTARIO, CANADA (PRWEB) , ... July 21, ... ... with over 80% follow-up at 10 years, researchers from the Multicenter Orthopaedics Outcome ... knee-related quality of life a decade after surgery, though activity levels decline over ...
(Date:7/20/2017)... Viejo, CA (PRWEB) , ... July 20, 2017 , ... ... when placed between two clips in the FCPX timeline. This effect isolates horizontal and ... transition in this package contains either a rotating or flipping animation and can be ...
(Date:7/20/2017)... July 20, 2017 (PRWEB) , ... ... ... Technologies, a global provider of enterprise-grade IT operations analytics and application performance ... of one of world’s largest healthcare services providers. , According to Peter ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... 2017  BDI Group subsidiary Pathway Purchasing Network, ... organization serving specialty pharmacies, home infusion companies and ... significant, value-added member programs designed to help organizations ... and improve access and affordability for patients who ... Pathway has worked ...
(Date:7/6/2017)... -- ThriveRx, the nutrition division of Diplomat Specialty Infusion Group, is celebrating ... support. To celebrate its anniversary, ThriveRx recently launched a redesigned ... look with improved organization to create the best user experience for consumers ... ... "We,ve made several great strides throughout ...
(Date:7/5/2017)... July 5, 2017 Pace Analytical, a company of over 2,000 employees ... they have acquired ESC Lab Sciences, further solidifying their position as the top ... . ... President and CEO of Pace Analytical ... Sciences out of Mt Juliet, TN , enhances Pace Analytical,s ...
Breaking Medicine Technology: