Navigation Links
Professor Develops Blood Test for Alzheimer’s Disease Risk
Date:7/29/2014

Pomona, California (PRWEB) July 29, 2014

A team of scientists, led by Western University of Health Sciences Professor Doug Ethell, PhD, has developed a blood test for Alzheimer’s disease risk that may lead to earlier detection and the development of Alzheimer’s disease interventions, according to an article published July 29, 2014.

“Alzheimer’s disease is a puzzle, and this study represents one of several pieces that have locked into place for us over the past couple of years,” Ethell said.

The study, “Women with the Alzheimer's risk marker ApoE4 lose Aß-specific CD4+ T cells 10-20 years before men,” describes how the new test gauges the immune responses to a component of brain plaques associated with the disease. Carriers of the Alzheimer’s risk factor ApoE4 showed an earlier decline in this response than non-carriers, by about a decade.

Women showed an earlier decline than men, which is consistent with a 2.5-fold higher risk of Alzheimer’s disease. Women who carried ApoE4 showed the earliest decline of any group, with a precipitous drop found between the ages of 45 and 52, when menopause typically begins.

Aß-specific CD4+ T cells have a central role in regulating adaptive immune responses to antigens, and have been shown to reduce AD pathology in mouse models. As these cells may facilitate endogenous mechanisms that counter AD, an evaluation of their abundance before and during AD provides important insights, according to the study.

“It’s very exciting because it changes the way we think about this disease, and opens the door to some interesting possibilities,” Ethell said.

The assay may provide an early indicator of changes that precede Alzheimer’s disease by a decade or more by quantifying Aß-specific CD4+ T cells in human blood. This assay, called CD4see, could accelerate clinical testing of new Alzheimer’s disease interventions that require an early biomarker.

“Our
'/>"/>

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2

Related medicine news :

1. Louisiana Tech University professor earns NSF Early Career Development grant
2. Clemson professor awarded nearly $600,000 4-year grant to study language of plants
3. Louisiana Tech biomedical engineering professor earns recognition, funding for research
4. Women professorships low in some Scandinavian universities due to sexism
5. President Obama names SF State math professor a top young scientist
6. From textbook to flexbook: Professor uses new collaborative tool in the classroom
7. IHME professor named first health measurement winner of prestigious innovation award
8. Guys, take note: Male birth control pill may be ready soon, says Texas A&M professor
9. UBC professor wins Canadas top pharmaceutical research award
10. Huddersfield professors ground-breaking research shows just how well the 2012 Games were run
11. Grove Professor receives $1.5MM to study breast cancer therapies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... (PRWEB) March 03, 2015 Human ... that it’s offering a new master health insurance plan ... its clients with a group platform removing potential cost ... Master Health Plan has been in effect since January ... clients with much need medical cost savings. , The ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 Sponsors of ... have an abundance of significant proposed changes to sift ... and preliminary 2016 Call Letter released Feb. 20. The ... they will vary considerably with the type and location ... to analyze and comment on them before CMS issues ...
(Date:3/3/2015)... IL (PRWEB) March 03, 2015 ISI ... solutions, will be sponsoring the 2015 Cisco Geekfest in ... to bring Cisco’s partners together to discuss the overall ... agenda is a dynamic keynote address from Martin Roesh, ... Group. The event will also include two days ...
(Date:3/3/2015)... NY (PRWEB) March 03, 2015 ... high-quality, clinically-based care management programs and a member ... the appointment of Julie O’Brien as President. O’Brien ... Chief Operating Officer. In her new role, she ... for all aspects of AMM’s call center operations, ...
(Date:3/3/2015)... HealthCarePoint (HCP) , the ... today that it has completed development of the ... Standards Consortium (CDISC). HCP will continue to provide ... training and certifications globally. HCP’s in-kind services will ... as well as development of dynamic identification for ...
Breaking Medicine News(10 mins):Health News:HCBR Group Offers Master Healthcare Plan through Humana 2Health News:March 12 Webinar to Analyze Implications of CMS’s ’45-Day Notice’ and 2016 Call Letter for MA and Part D Plans 2Health News:ISI Telemanagement Solutions, Inc. to Sponsor 2015 Cisco Geekfest 2Health News:Julie O'Brien Named President of AliCare Medical Management 2Health News:Julie O'Brien Named President of AliCare Medical Management 3Health News:HealthCarePoint Completes CDISC BlueCloud Transnational Commerce Through In-kind Donations 2Health News:HealthCarePoint Completes CDISC BlueCloud Transnational Commerce Through In-kind Donations 3
... DENVER, Feb. 4 The American Board ... Simulations, using Medical,Simulation Corporation,s (MSC) SimSuite(R) technology, ... This is the first time ABIM is,incorporating ... evaluate,physician competence., SimSuite technology replicates a ...
... clinical nomogram tool, the Sunnybrook Prostate Cancer Risk Calculator ... for prostate cancer is available online to help ... their primary care physician. A nomogram is a ... risk factors using a table and chart format. , ...
... Washington, D.C. More than half a million women ... United States, use natural family planning methods developed by ... of these women and thousands of others use CycleBeads ... women manage their fertility to plan or prevent pregnancy. ...
... The Burden of Rheumatoid Arthritis and Patient Access to ... (Sweden), the University of Lund (Sweden) and the Medical ... cost in rheumatoid arthritis results from patients having to ... The study has just been published online in a ...
... Sunrise Senior Living Communities Provide Insight ... into Their 50+-year Relationships, MCLEAN, Va., Feb. 4 ... providers of senior living services with,more than 450 communities worldwide, shared ... married 50+ years and spent more than,five decades of special Valentine,s ...
... 4 The American Academy of,Pediatrics (AAP) and its ... its World Cancer Day initiative Monday, February 4,to promote ... safe level of tobacco smoke exposure," said Renee R.,Jenkins, ... no safe way,to smoke around children. Smoking in another ...
Cached Medicine News:Health News:Medical Simulation Corporation and the American Board of Internal Medicine Introduce New Simulation for Physician Assessment and Evaluation 2Health News:Online tool supports more dialogue on prostate cancer risk 2Health News:CycleBeads help women manage their fertility 2Health News:Rheumatoid arthritis sends many into early retirement 2Health News:Secrets to Long-Lasting Marriages Revealed in Senior Survey 2Health News:Secrets to Long-Lasting Marriages Revealed in Senior Survey 3Health News:AAP Calls for Smoke-Free Environments for World Cancer Day 2
(Date:3/3/2015)... , March 3, 2015  Cannabis Science, Inc. ... of cannabis-based medicine, today announced two important developments: It ... multiple global product launches, and CEO Raymond C. ... Chicago HR Examiner. In the article, Dabney ... about leading a company in an industry that is ...
(Date:3/3/2015)... 2015  Tru-D SmartUVC will exhibit the cutting-edge ... Registered Nurses, Surgical Conference and Expo 2015 in ... Safety Awareness Week March 7 through 11. AORN ... practice and professional development. Photo ... http://photos.prnewswire.com/prnh/20150302/178998LOGO   Tru-D SmartUVC,s UV ...
(Date:3/3/2015)... Research and Markets ( http://www.researchandmarkets.com/research/tvmk72/the_generic_drugs ... new report "The Generic Drugs Market: 2015 ... to their offering. , ... intended to be interchangeable with an innovator product, ... innovator company and marketed after the expiry date ...
Breaking Medicine Technology:CBIS Momentum Continues: Company Opens Call Center In Preparation For New Product Releases & CEO Shares His 'Impressive And Insightful' Views With Columnist 2CBIS Momentum Continues: Company Opens Call Center In Preparation For New Product Releases & CEO Shares His 'Impressive And Insightful' Views With Columnist 3CBIS Momentum Continues: Company Opens Call Center In Preparation For New Product Releases & CEO Shares His 'Impressive And Insightful' Views With Columnist 4CBIS Momentum Continues: Company Opens Call Center In Preparation For New Product Releases & CEO Shares His 'Impressive And Insightful' Views With Columnist 5Tru-D SmartUVC to Exhibit Most Effective UV Disinfection Robot at AORN Surgical Conference and Expo 2015 2Tru-D SmartUVC to Exhibit Most Effective UV Disinfection Robot at AORN Surgical Conference and Expo 2015 3Generic Drugs a $350 Billion Opportunity According to 'The Generic Drugs Market: 2015-2030 - Opportunities, Challenges, Strategies & Forecasts' 2Generic Drugs a $350 Billion Opportunity According to 'The Generic Drugs Market: 2015-2030 - Opportunities, Challenges, Strategies & Forecasts' 3Generic Drugs a $350 Billion Opportunity According to 'The Generic Drugs Market: 2015-2030 - Opportunities, Challenges, Strategies & Forecasts' 4Generic Drugs a $350 Billion Opportunity According to 'The Generic Drugs Market: 2015-2030 - Opportunities, Challenges, Strategies & Forecasts' 5Generic Drugs a $350 Billion Opportunity According to 'The Generic Drugs Market: 2015-2030 - Opportunities, Challenges, Strategies & Forecasts' 6
... CARSON CITY, Nev., April 11, 2011 Rapid ... announced today that their wholly owned subsidiary, Medical ... legal channels to begin cultivation and growing of medical ... of the Company,s business will significantly increase revenue and ...
... GREENVILLE, S.C., April 11, 2011 KEMET Corporation ... of tantalum, ceramic, aluminum, film, paper and electrolytic ... (TSM) Series capacitors. The TSM Series is targeted ... space in the computer, consumer/gaming, medical, military/aerospace, telecommunications ...
Cached Medicine Technology:Rapid Fire Marketing: Medical Cannabis Management Cleared for Medical Cannabis Cultivation 2KEMET Introduces Tantalum Stacked Capacitors 2KEMET Introduces Tantalum Stacked Capacitors 3