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Product Shifts are Occurring in the Renal Anemia and Bone and Mineral Metabolism Markets According to the Most Recent TreatmentTrends(R): US Nephrology Report from BioTrends Research Group
Date:4/27/2009

o each have approximately 36% market share. In both the dialysis and CKD markets, Nephrologists project increases in the use of Renvela and Shire's Fosrenol primarily at the expense of PhosLo and Renagel.

The use of Nutritional Vitamin D is on the rise, particularly among CKD Stage 3 and 4 patients, where Nephrologists report approximately 35% of patients are treated with these agents. Despite this increase, treatment prevalence with Active Vitamin D has remained stable across all patient groups compared to the same period last year. Abbott's Zemplar continues to hold the position of market leader among hemodialysis patients, and in a shift from the same quarter last year when calcitriol was the market leader in CKD, Zemplar now holds that position. Nephrologists report that barriers to increased use of both Zemplar and Genzyme's Hectorol in CKD center around reimbursement and incidences of hypercalcemia and hyperphosphatemia. Amgen's Sensipar continues to be used in less than one third of dialysis patients, although Nephrologists continue to project significant increases in the next three months.

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SOURCE BioTrends Research Group, Inc.
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