Navigation Links
Procedure developed at Yale creates new bone
Date:2/14/2008

A new technique that combines bone marrow removal and injection of a hormone helps promote rapid formation of new bone at targeted locations in the body, it was reported by Yale School of Medicine this month in Tissue Engineering.

"This could radically change the way patients are currently treated for weakened or fractured hips, vertebrae and acute traumatic long bone fractures," said senior author Agns Vignery, associate professor of orthopedics.

She said currently available treatment requires surgery and artificial materials and often results in imperfect outcomes. "The ideal approach would be to create new bone where it is needed and at a faster rate," Vignery said.

The study in mice was done in collaboration with Unigene Laboratories, Inc. It evaluated the effect of bone marrow removal from particular sites followed by daily injections of anabolic agents such as parathyroid hormone (PTH).

The procedure creates new bone tissue that appears structurally and biologically normal and that endows the targeted bone with improved biomechanical properties at a rate and extent that would not be achievable by anabolic therapy alone, Vignery said.

"We have shown that it is the synergistic effect of mechanical marrow ablation and PTH that allows for this new bone to fill the marrow cavity," she said.

She said additional studies are underway that extend the results of this work in other animals and that will determine whether the newly formed bone can be preserved over a long period of time.


'/>"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
Source:Eurekalert

Page: 1

Related medicine news :

1. UK junior doctors gaining less experience of common procedures
2. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
3. Eligard(R) six-month formulation successfully completes European approval procedure
4. Smoking can harm the long-term effects of some oral surgery procedures
5. Photo: Kyphon and the X-STOP(R) IPD(R) Procedure to be Featured on American Health Radio on Monday, September 24, 2007
6. Study Shows Cosmetic Surgery on the Rise as Safety and Efficacy of Procedures Increase
7. New Device for Clearing Blocked Arteries in the Legs Receives FDA Clearance for Peripheral Use - Procedures Performed Across the US Within First 48 Hours
8. Orthopedic Development Corporations TruFUSE(R) Procedure Tops 1,750 Patients in First Year
9. Decrease in the use of radiotherapy procedures for the treatment of cancer in hospitals
10. Prominent Farmington Plastic Surgeon Uses Two New Non-Surgical Procedures to Tighten Skin and Remove Fat
11. UI researchers seek to ease childrens pain during medical procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 2017 , ... PurhealthRX , a leading Health and Nutrition Company, is ... to full spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing ... easily incorporated into liquid products, while reducing costs to end users. , The team ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... 2017  True Health, a leader in integrated ... during National Breast Cancer Awareness month to educate ... Research recently published ... more than 10 million American women are at ... or BRCA2 and have not had testing. These mutations ...
(Date:10/10/2017)... 10, 2017   West Pharmaceutical Services, Inc. ... injectable drug administration, today shared the results of a ... improving the intradermal administration of polio vaccines. The study ... in May 2017 by Dr. Ondrej Mach , ... Health Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... SEOUL, South Korea , Oct. 4, 2017 /PRNewswire/ ... launched its next-generation CPR training aide "cprCUBE" on Kickstarter. ... of chest compression during cardiac arrests with better efficiency ... patient-mannequins. It also offers real-time feedback on efficacy of ... The crowdfunding campaign has a goal to raise ...
Breaking Medicine Technology: