Navigation Links
Procedure developed at Yale creates new bone
Date:2/14/2008

A new technique that combines bone marrow removal and injection of a hormone helps promote rapid formation of new bone at targeted locations in the body, it was reported by Yale School of Medicine this month in Tissue Engineering.

"This could radically change the way patients are currently treated for weakened or fractured hips, vertebrae and acute traumatic long bone fractures," said senior author Agns Vignery, associate professor of orthopedics.

She said currently available treatment requires surgery and artificial materials and often results in imperfect outcomes. "The ideal approach would be to create new bone where it is needed and at a faster rate," Vignery said.

The study in mice was done in collaboration with Unigene Laboratories, Inc. It evaluated the effect of bone marrow removal from particular sites followed by daily injections of anabolic agents such as parathyroid hormone (PTH).

The procedure creates new bone tissue that appears structurally and biologically normal and that endows the targeted bone with improved biomechanical properties at a rate and extent that would not be achievable by anabolic therapy alone, Vignery said.

"We have shown that it is the synergistic effect of mechanical marrow ablation and PTH that allows for this new bone to fill the marrow cavity," she said.

She said additional studies are underway that extend the results of this work in other animals and that will determine whether the newly formed bone can be preserved over a long period of time.


'/>"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
Source:Eurekalert

Page: 1

Related medicine news :

1. UK junior doctors gaining less experience of common procedures
2. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
3. Eligard(R) six-month formulation successfully completes European approval procedure
4. Smoking can harm the long-term effects of some oral surgery procedures
5. Photo: Kyphon and the X-STOP(R) IPD(R) Procedure to be Featured on American Health Radio on Monday, September 24, 2007
6. Study Shows Cosmetic Surgery on the Rise as Safety and Efficacy of Procedures Increase
7. New Device for Clearing Blocked Arteries in the Legs Receives FDA Clearance for Peripheral Use - Procedures Performed Across the US Within First 48 Hours
8. Orthopedic Development Corporations TruFUSE(R) Procedure Tops 1,750 Patients in First Year
9. Decrease in the use of radiotherapy procedures for the treatment of cancer in hospitals
10. Prominent Farmington Plastic Surgeon Uses Two New Non-Surgical Procedures to Tighten Skin and Remove Fat
11. UI researchers seek to ease childrens pain during medical procedures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... 30, 2014 One of the most recent ... the gluten-free diet. Originally meant for sufferers of gluten intolerance ... for people who are looking to get healthier by simply ... is this kind of information erroneous, it also exposes those ... because of a drastic change in their food consumption habits. ...
(Date:8/30/2014)... Removecomplaints.net, a well-known name in the world ... offer guarantee of results with its complaint removal services. ... of its tremendous track record. The company has successfully ... the world and received recommendation letters from many of ... being asked about the announcement, a senior management executive ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 Ms. Meriwether’s striking ... She certainly has an impressive resume to boost. ... USA in 2012. However, she’s also a two time ... student. Nana trained for the 2008 Olympics and played ... USA website, “This six-foot beauty from Potomac, Maryland is a ...
(Date:8/30/2014)... 30, 2014 McLeod's Sunset Park Auto ... repair shop with strong ties to the community celebrates sixty ... to announce they have been chosen by The Tampa ... auto repair. , Tim McLeod’s father, Norris (most know ... years ago. Although his son, Tim runs the day to ...
(Date:8/30/2014)... As 500 Zoloft lawsuits pending ligation contend the ... mothers, Wright & Schulte LLC recently learned of a remand ... remand in the Zoloft lawsuits was granted to ... involved in one SSRI lawsuit filed jointly under ... defect lawsuit sent back to the Missouri state court in ...
Breaking Medicine News(10 mins):Health News:“What is Gluten: Three Things You Need to Know Before Adopting a Gluten-Free Diet” Reveals What Readers Need to Know About the Benefits of a Strict Gluten Diet - Vinamy 2Health News:Removecomplaints.net Announces Guaranteed Complaints Removal Services 2Health News:NJ Top Dentists Announces Cover Model for the Healthy Living: Top Dentists Issue 2Health News:McLeod's Sunset Park Auto Service Celebrates 60 Years Honored with Best of South Tampa 2Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 2Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 3Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 4Health News:Group of Plaintiffs in Zoloft Lawsuit Alleging SSRI Caused Birth Defect Are Granted Remand 5
... HILLS, Calif., June 11 The Jonsson Cancer,Center ... raising,private funds for highest priority cancer research, hosts ... 21, at the Beverly Wilshire Hotel. FOX,Broadcasting Company ... Humanitarian Award. Jimmy Kimmel hosts the event and ...
... LAUREL, N.J., June 11 MedQuist Inc.,(Pink Sheets: MEDQ.PK). ... the District of New Jersey dismissed the South Broward ... and good cause shown,within 60 days, to reopen the ... in the process of informing the court that the ...
... Institute of Allergy and Infectious Diseases (NIAID), part of the ... George W. Bush with the Presidential Medal of Freedom at ... , The White House noted today that Dr. Fauci ... knowledge. His efforts to advance our understanding and treatment of ...
... PLAINS, NY Experts from throughout the United States will ... the growing crisis of preterm birth. , The conference, ... RADM, USPHS and the Eunice Kennedy Shriver National Institute of ... 16 and 17 in Rockville, MD. It is a ...
... While consumers are increasing demand for pork produced ... such conditions carry bacteria and parasites associated with ... A comparison of swine raised in antibiotic-free and ... outdoors without antibiotics had higher rates of three ...
... some into remission, study says , , WEDNESDAY, June ... golimumab to weekly doses of methotrexate helped most ... into remission, two new studies show. , The ... biologic therapy drug, were scheduled to be presented ...
Cached Medicine News:Health News:American Idol Winner David Cook to Perform at and Jimmy Kimmel to Host Jonsson Cancer Center Foundation's 'Taste for a Cure' on June 21 2Health News:MedQuist Announces Dismissal of South Broward Litigation and Appointment of New Interim President & CEO 2Health News:MedQuist Announces Dismissal of South Broward Litigation and Appointment of New Interim President & CEO 3Health News:MedQuist Announces Dismissal of South Broward Litigation and Appointment of New Interim President & CEO 4Health News:Experts to develop national response to growing crisis of premature birth 2Health News:Pigs raised without antibiotics more likely to carry bacteria, parasites 2Health News:Pigs raised without antibiotics more likely to carry bacteria, parasites 3Health News:Pigs raised without antibiotics more likely to carry bacteria, parasites 4Health News:Golimumab Eases Rheumatoid Arthritis Symptoms 2
(Date:8/29/2014)... Md. , Aug. 29, 2014  United Therapeutics ... the U.S. District Court for the District of ... favor in the company,s case against Sandoz, Inc. regarding ... Peter Sheridan ruled that U.S. Patent No. ... and enjoined Sandoz from marketing its generic product until ...
(Date:8/29/2014)... 2014 /PRNewswire-iReach/ -- ChemImage will present a workshop focused ... Zealand Forensic Science Society,s 22 nd International ... Adelaide, Australia .  Forensic Scientists will be ... hyperspectral imaging can bring to examination procedures. ... of Product Development at ChemImage, will host a ...
(Date:8/29/2014)... British Columbia and MENLO PARK, ... DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" "the ... fiscal year-end financial statements.  The Company recently changed its ... facilitate an application to list its common stock on ... DelMar,s financial statements as filed with the ...
Breaking Medicine Technology:District Court Decision Received In Remodulin Patent Case 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5
... , Aug. 4 /PRNewswire-Asia-FirstCall/ -- American Oriental,Bioengineering, Inc. (NYSE: ... to improving health through the development, manufacture and,commercialization of a broad range ... to release second quarter 2010,financial results on Monday, August 9, 2010 ... , , ...
... SHENZHEN, China , Aug. 4 ... NPD ) ("Nepstar" or "the Company"), the largest ... of directly operated stores,today announced that the State Administration of ... the amount of RMB25.5 million ,( US$3.8 million ) ...
Cached Medicine Technology:American Oriental Bioengineering to Report Second Quarter 2010 Financial Results on August 9, 2010 2China Nepstar Chain Drugstore Reports One-time Non-recurring Penalty Payment 2China Nepstar Chain Drugstore Reports One-time Non-recurring Penalty Payment 3China Nepstar Chain Drugstore Reports One-time Non-recurring Penalty Payment 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: