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Procedure Lowers 'Hunger Hormone' to Help Obese Lose Weight
Date:3/7/2013

his procedure is a type of gastric artery embolization that has been used for years to treat bleeding in the intestines and reduce side effects from chemotherapy for advanced liver cancer.

Whether there will be complications down the line or whether patients will gain the weight back, as many do after other weight-loss surgery, isn't clear, Kipshidze said.

"Who knows with this procedure whether patients will gain the weight back? I cannot tell you; I don't know what is going to happen," he said.

That answer is the key to whether this procedure will be a viable alternative to other types of weight-loss surgery, another expert said.

"The question is, will this thing work in a lot of people over a long period of time, and what's the complication rate and what's the mortality with it," said Dr. Stephen Green, associate chairman of the department of cardiology at North Shore University Hospital in Manhasset, N.Y.

"If this works, it would be fantastic -- it would be a game changer," he said. "But this is not ready for prime time."

Kipshidze is planning larger clinical trials where some patients -- including some with diabetes -- will undergo the procedure while others will have a sham procedure. In all, they will need to include about 30 patients to be sure the procedure is safe and effective, he said. The procedure is also being refined with new equipment and techniques.

More information

For more about obesity, visit the U.S. National Library of Medicine.

SOURCES: Nicholas Kipshidze, M.D., Ph.D., New York Cardiovascular Research, New York City, and physician-in-chief and general director, Republican Hospital, Tbilisi, Georgia; Stephen Green, M.D., associate chairman, department of cardiology, North Shore University Hospital, Manhasset, N.Y; David Katz, M.D., M.P.H., director, Yale University Prevention Research Cen
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