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Princeton study reveals the brain's mysterious switchboard operator
Date:8/17/2012

A mysterious region deep in the human brain could be where we sort through the onslaught of stimuli from the outside world and focus on the information most important to our behavior and survival, Princeton University researchers have found.

The researchers report in the journal Science that an area of our brain called the pulvinar regulates communication between clusters of brain cells as our brain focuses on the people and objects that need our attention. Like a switchboard operator, the pulvinar makes sure that separate areas of the visual cortex which processes visual information are communicating about the same external information, explained lead author Yuri Saalmann, an associate research scholar in the Princeton Neuroscience Institute (PNI). Without guidance from the pulvinar, an important observation such as an oncoming bus as one is crossing the street could get lost in a jumble of other stimuli.

Saalmann said these findings on how the brain transmits information could lead to new ways of understanding and treating attention-related disorders, such as attention deficit hyperactivity disorder (ADHD) and schizophrenia. Saalmann worked with senior researcher Sabine Kastner, a professor in the Department of Psychology and the Princeton Neuroscience Institute; and PNI researchers Xin Li, a research assistant; Mark Pinsk, a professional specialist; and Liang Wang, a postdoctoral research associate.

[Images can be seen at http://www.princeton.edu/main/news/archive/S34/52/20C50. To obtain high-res images, contact Princeton science writer Morgan Kelly, (609) 258-5729, mgnkelly@princeton.edu]

The researchers developed a new technique to trace direct communication between clusters of neurons in the visual cortex and the pulvinar. The team produced neural connection maps using magnetic reso
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Contact: Morgan Kelly
mgnkelly@princeton.edu
609-258-5729
Princeton University
Source:Eurekalert  

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Princeton study reveals the brain's mysterious switchboard operator
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