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Princeton scientists discover mechanism involved in breast cancer's spread to bone
Date:2/3/2011

the near future.

According to Kang, there are few drugs currently available to relieve symptoms associated with bone metastases, and none is able to completely stop the cancer. If Kang's findings lead to a drug that can halt or slow this process, it could affect the 200,000 patients that the NCI estimates are diagnosed every year with breast cancer. It might work for some other cancer patients as well, Kang said.

Sloan-Kettering's Bromberg said Kang's recent discovery "underlies the importance of targeting the environmental milieu" in which disease develops, in this case the activity of the Notch signaling pathway and specific interactions between cancer cells and the specialized cells that break down and rebuild bone.


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Contact: Emily Aronson
earonson@princeton.edu
609-258-5733
Princeton University
Source:Eurekalert  

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