Navigation Links
Primate Immune System Differences Identified
Date:12/17/2010

FRIDAY, Dec. 17 (HealthDay News) -- Differences in immune signaling pathways among various species may explain why humans are more susceptible than other primates to certain infectious diseases, researchers say.

For example, when it comes to the progression of HIV to AIDS or severe complications from hepatitis B, it has been found that humans are more sensitive than chimpanzees to the serious effects of these viral infections, noted Luis B. Barreiro of the University of Chicago and colleagues.

In the new study, published in the Dec. 16 online edition of the journal PLoS Genetics, Barreiro's team conducted the first genome-wide comparison of genes regulated by the innate immune system in humans, chimpanzees and rhesus macaques. In order to identify functional differences in their immune pathways, the researchers stimulated immune cells from each of the three primate species.

The core response needed to fight any invading pathogen was similar in all three species. But there were differences in how the immune system fought off certain viral and microbial infections. This likely reflects rapid adaptation cycles between specific hosts and viruses, the study authors said.

One particularly interesting finding was that many HIV-interacting genes responded uniquely in chimpanzees, which may help explain why chimpanzees do not routinely develop AIDS after being infected with HIV, the study authors noted in a news release from the journal's publisher.

The researchers also found that human immune responses were particularly enriched for genes involved in cell death and cancer biology.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about the immune system.

-- Robert Preidt

SOURCE: PLoS Genetics, news release, Dec. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. BUAV Exposes Shocking Role Played by Laos in the International Trade in Primates for Research
2. UCSF team finds new source of immune cells during pregnancy
3. Vaccine boosts your immune system
4. UCSF fountain of youth pill could restore aging immune system
5. 2009 H1N1 vaccine safe and induces robust immune response in people with asthma
6. Over-reactive immune system kills young adults during pandemic flu
7. Research Finds Not All HIV Affects Immune System Same Way
8. Toxins from Staph Bacteria Disrupt Immune System
9. Too Much Hygiene May Affect Immune System, Study Suggests
10. New study reveals how cannabis suppresses immune functions
11. BUSM investigates cellular mechanisms leading to immune response in airway epithelium
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Primate Immune System Differences Identified
(Date:6/24/2016)... ... 2016 , ... To succeed under value-based payments, healthcare providers ... how to move forward, given the need to sustain current operations. PYA has ... an organization’s specific needs. , PYA Principal Martie Ross states, “Healthcare providers want ...
(Date:6/24/2016)... Brooklyn, New York (PRWEB) , ... June 24, 2016 , ... ... medical marijuana patients optimize the ingestion of their medication by matching users with high ... allows users to compare pieces with no commitment. , Inhale was founded by two ...
(Date:6/24/2016)... ... ... Dr. Seema Daulat, a native Texan and University of Texas at Austin ... July 13, 2016. , Dr. Daulat earned her Doctorate of Medicine (MD) at The ... the Agape Clinic serving Dallas’ underprivileged community. , Following medical school, Dr. Daulat completed ...
(Date:6/23/2016)... Los Angeles, CA (PRWEB) , ... June 23, 2016 , ... ... being conducted that may expose a possible link between head and neck cancer in ... individuals participating in the study were evaluated based on whether they had gum disease, ...
(Date:6/23/2016)... ... ... The Mechille Wilson Agency, a Texas-based insurance company that provides coverage to hundreds ... a charity drive to assist a student to be chosen from the local area. ... be presented to the chosen student to help with the growing costs of tuition, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Bracket , a leading clinical ... generation clinical outcomes platform, Bracket eCOA (SM) 6.0, at ... 26 – 30, 2016 in Philadelphia , ... Outcome Assessment product of its kind to fully integrate with ... Bracket eCOA 6.0 is a flexible platform for electronic clinical ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... 2016 Revolutionary technology includes multi-speaker ... , industry leaders in advanced audiology and hearing aid ... Opn ™, the world,s first internet connected hearing aid ... devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) ... of ,world firsts,: , TwinLink™ - the ...
Breaking Medicine Technology: