Navigation Links
Primate Immune System Differences Identified
Date:12/17/2010

FRIDAY, Dec. 17 (HealthDay News) -- Differences in immune signaling pathways among various species may explain why humans are more susceptible than other primates to certain infectious diseases, researchers say.

For example, when it comes to the progression of HIV to AIDS or severe complications from hepatitis B, it has been found that humans are more sensitive than chimpanzees to the serious effects of these viral infections, noted Luis B. Barreiro of the University of Chicago and colleagues.

In the new study, published in the Dec. 16 online edition of the journal PLoS Genetics, Barreiro's team conducted the first genome-wide comparison of genes regulated by the innate immune system in humans, chimpanzees and rhesus macaques. In order to identify functional differences in their immune pathways, the researchers stimulated immune cells from each of the three primate species.

The core response needed to fight any invading pathogen was similar in all three species. But there were differences in how the immune system fought off certain viral and microbial infections. This likely reflects rapid adaptation cycles between specific hosts and viruses, the study authors said.

One particularly interesting finding was that many HIV-interacting genes responded uniquely in chimpanzees, which may help explain why chimpanzees do not routinely develop AIDS after being infected with HIV, the study authors noted in a news release from the journal's publisher.

The researchers also found that human immune responses were particularly enriched for genes involved in cell death and cancer biology.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about the immune system.

-- Robert Preidt

SOURCE: PLoS Genetics, news release, Dec. 16, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. BUAV Exposes Shocking Role Played by Laos in the International Trade in Primates for Research
2. UCSF team finds new source of immune cells during pregnancy
3. Vaccine boosts your immune system
4. UCSF fountain of youth pill could restore aging immune system
5. 2009 H1N1 vaccine safe and induces robust immune response in people with asthma
6. Over-reactive immune system kills young adults during pandemic flu
7. Research Finds Not All HIV Affects Immune System Same Way
8. Toxins from Staph Bacteria Disrupt Immune System
9. Too Much Hygiene May Affect Immune System, Study Suggests
10. New study reveals how cannabis suppresses immune functions
11. BUSM investigates cellular mechanisms leading to immune response in airway epithelium
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Primate Immune System Differences Identified
(Date:5/2/2016)... ... ... It has just been announced Jack Uldrich, renowned futurist and ... of May. , Uldrich is the author of 11 books and a regular guest ... the Science Channel’s FutureScape and Discovery Channel’s Inside Out. , Known the world over ...
(Date:5/2/2016)... ... May 02, 2016 , ... As directed by its board of ... issues its full support to allow certified nurse practitioners (CNP) to practice to the ... worked under such supervision for three years and 3,600 hours. , In addition, HAP ...
(Date:5/2/2016)... ... ... Eating Recovery Center’s Insight Behavioral Health Center (ERC Insight) , a ... eating disorder program under a new name: Eating Recovery Center, Chicago (ERC Chicago). ERC ... , To celebrate, ERC Chicago will host a ribbon-cutting ceremony and open house on ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... for the 2016 Main Residency Match® (“the Match”), the system through which U.S. ... teaching institutions. A record-high 30,750 positions were placed in the 2016 Match, and ...
(Date:5/2/2016)... ... , ... East Los Angeles dentist , Dr. Ramin Assili, is now ... receive any dental extraction treatment for $40 off the regular price. This promotion cannot ... lower price, patients can more easily afford extractions to eliminate teeth that are damaged ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016  The blood testing market in ... Kalorama Information and The Freedonia Group in a recent ... testing.  The healthcare research firm said that ... collection stations and in improving testing at the provincial ... Blood Testing Market in China , ...
(Date:4/28/2016)... -- , Net Sales of $1.90 billion represent an ... year period, and an increase of 1.2% on an adjusted ... the first quarter were $0.52 reported, a decrease of 47.5% ... of 29.9% over the prior year period , The ... 2016 Zimmer Biomet Holdings, Inc. (NYSE and SIX: ...
(Date:4/28/2016)... 28, 2016 Oramed Pharmaceuticals Inc. (NASDAQ: ... company focused on the development of oral drug delivery systems, ... PIONEERS 2016 conference, presented by Joseph Gunnar & ... New York . Nadav Kidron , CEO ... Presentation Details:   PIONEERS 2016, ...
Breaking Medicine Technology: