Navigation Links
Primary androgen deprivation therapy ineffective for most men with early prostate cancer
Date:3/17/2014

WASHINGTON A study of more than 15,000 men with early stage prostate cancer finds that those who received androgen deprivation as their primary treatment instead of surgery or radiation did not live any longer than those who received no treatment.

The research team, led by scientists at Georgetown Lombardi Comprehensive Cancer Center, say that the risks of serious adverse events associated with the treatment which has been linked to impaired cognition, heart disease, diabetes and other disorders "mitigates against any clinical or policy rationale for use of primary androgen deprivation therapy in these men."

The findings, reported Monday in the Journal of Clinical Oncology, draw from cancer registries linked with extensive electronic medical records in three, large integrated health plans. The men included in the study had prostate cancer that had not spread beyond the organ (localized) and did not have surgery or radiation therapy, considered curative treatment.

Androgen deprivation therapy suppresses the production of testosterone, the male hormone said to fuel growth of prostate cancer. The therapy improves survival when given with radiation for later stages of disease, and is considered the standard of care for men who have metastatic prostate cancer. Effectiveness of primary androgen deprivation therapy (PADT) has not been established.

"This study is the most comprehensive study on the effectiveness of PADT for men who forgo radiation and surgery for their localized prostate cancer, and it tells us there is no strong reason to use it in most patients," says the study's lead investigator, Arnold Potosky, PhD, a professor of oncology and director of health services research at Georgetown Lombardi. "We found only a small survival benefit for primary androgen deprivation therapy compared to no therapy in men diagnosed with higher-risk localized prostate cancer."

Use of primary androgen deprivation therapy for early stage prosta
'/>"/>

Contact: Karen Teber
km463@georgetown.edu
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Rural primary care physicians are committed to professionalism, quality improvement
2. New study shows core factors and strategies to turn primary care practices into PCMHs
3. Katie Johnson, Author of Red Flags for Primary Teachers, Works with Fifth Graders to Investigate Their VIsion Problems When Reading
4. Live Primary Care CME (Continuing Medical Education) Faculty and Agenda Announced for Presidents' Week Conference in February 2014 to Be Held in Maui, Hawaii
5. Sunflower Medical Group Opens New Heartland Primary Care Location in Lenexa with Urgent Care Clinic
6. Center for Primary Care Celebrates 20th Anniversary
7. Primary care key to management of patients with HIV infection
8. Expanding primary care capacity by reducing inefficiency
9. Red Flags for Primary Teachers, Katie Johnson's Book about Children's Vision, Wins in The Great Midwest Book Festival Contest
10. Anxiety help comes, eventually, via primary care
11. Physician shortage could be cut by new primary care models, study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... (PRWEB) January 22, 2015 The federal court ... the U.S. District Court, Southern District of West Virginia has ... in that proceeding’s first bellwether trial. In an Order dated ... new trial after finding that C.R. Bard had not proven ...
(Date:1/22/2015)... 2015 For over 20 years, Dr. David Cruz ... Vista area has treated just about every type of injury ... And for those same twenty-plus years, the team at ... injuries with the best possible doctor. With the combined ...
(Date:1/22/2015)... January 23, 2015 Recently, Weddingshe.com has added ... and has announced its highest annual revenues in the past ... its popular glamorous wedding dresses. , According to the sales ... wedding dress promotions for them in 2015. This point can ...
(Date:1/22/2015)... York, NY (PRWEB) January 22, 2015 As ... of overall health care gains momentum worldwide, Rev. Eric ... HealthCare Chaplaincy Network (HCCN), will be the keynote ... spiritual care in Israel’s public health system. , The conference, ...
(Date:1/22/2015)... 22, 2015 State Forestry Institute of ... system with support from GEOSYSTEMS, a dedicated Hexagon Geospatial ... will leverage Hexagon Geospatial’s ERDAS APOLLO for ... well as point clouds and documents. This effort will ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
... Sept. 14 People,s United,Financial (Nasdaq: PBCT ) ... Klein, had undergone surgery to address a recurrence of,cancer ... surgery. He reported,in an e-mail to all employees that ... bank in early October. He stated that he is ...
... by Putting on Their Walking Shoes -, ... sedentary lifestyles by participating in the American,Heart Association ... other healthy habits in the workplace. AstraZeneca employees ... participate in,today,s Philadelphia Start! Heart Walk at Citizens ...
... lifelong dependence on insulin injections, researchers say , FRIDAY, ... gene can cause permanent neonatal diabetes, say American and ... in 21 people from 16 families. , Permanent neonatal ... infants and leads to lifelong dependence on insulin injections. ...
... Sept. 14 Saturday,September 15, will mark the first ... patient advocacy group, will be holding a,special Chicagoland cookout ... be food, outdoor games and other fun at North ... volunteer Greg Vandeventer will run,the combination awareness event, fundraiser ...
... MCLEAN, Va., Sept. 14 As part of USA ... USA",25- week charity program that highlights a different charity each ... and continued each Friday as USA TODAY,thanked America for its ... USA TODAY has selected 25 charities and has celebrated,the work ...
... than 90 EMS completions in past 10 years at the huge ... ... 13 Texas Aviation Services, an,industry leader in helicopter and aircraft ... offerings to,airborne EMS helicopter operators and hospital customers. On the eve ...
Cached Medicine News:Health News:AstraZeneca Joins Local Walking Movement 2Health News:AstraZeneca Joins Local Walking Movement 3Health News:AstraZeneca Joins Local Walking Movement 4Health News:Gene Mutations May Cause Rare Neonatal Diabetes 2Health News:Chicagoland Psoriasis Event Saturday Will Celebrate First National Short Sleeve Day 2Health News:USA TODAY Concludes 'Spirit of the USA' Charity Program as Part of Newspaper's 25th Anniversary Celebration 2Health News:USA TODAY Concludes 'Spirit of the USA' Charity Program as Part of Newspaper's 25th Anniversary Celebration 3Health News:Texas Aviation Services: Over 20 Years of Creating 'Flying Emergency Rooms' for Airborne EMS Customers in US and Latin America 2
(Date:1/23/2015)... Ala. , Jan. 23, 2015 Gem Pharmaceuticals ... patients have been enrolled into the Company,s Phase 2 ... and safety of Gem,s lead compound, GPX-150 (an investigational ... advanced or metastatic disease. Logo - ...
(Date:1/23/2015)... Jan. 23, 2015 Tianyin Pharmaceutical Inc. (NYSE Amex: ... in the development and sale of patented biopharmaceutical medicine, ... pharmaceutical ingredients (API) today announced the business and development ... 1. Following the September 2014 JCM application ...
(Date:1/22/2015)... BOULDER, Colo. , Jan. 22, 2015  BiOptix is ... Klakamp as Vice President of Chemistry and Biochemistry. Scott ... Takeda Pharmaceuticals, AstraZeneca Pharmaceuticals, and Amgen throughout the course ... and development. "Scott is a nationally recognized ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2
... Md. , April 27 The U.S. Food and Drug Administration ... and persistent asthma in certain adults. , ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ) , , ... Bronchial Thermoplasty System is intended for patients ages 18 and older whose severe ...
... (NYSE: CFN ) today announced plans to release third quarter results for ... on the New York Stock Exchange. , , ... will host a webcast and conference call on May 6 at ... results for its third quarter, ended on March 31, 2010 . To access ...
Cached Medicine Technology:FDA Approves New Device for Adults with Severe and Persistent Asthma 2FDA Approves New Device for Adults with Severe and Persistent Asthma 3CareFusion Will Host an Earnings Conference Call on May 6 to Discuss the Results for the Third Quarter of Fiscal 2010 2
VascoScrew is a low profile unipolar pacing lead with a fixed screw for permanent pacing. Due to latest technologies, VascoScrew 6/60 M is compatible to all pacemaker-cavities with the size of IS-1 (...
VascoScrew is a low profile unipolar pacing lead with a fixed screw for permanent pacing. Due to latest technologies, VascoScrew 6/60 M is compatible to all pacemaker-cavities with the size of IS-1 (...
The VascoTip J 9/60 PU is a unipolar tined, J-preformed permanent pacing lead. Due to advanced technology, VascoTip J 9/60 PU M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm),...
Steroid-eluting, epicardial pacing leads...
Medicine Products: