Navigation Links
Primary Tumors Fuel Growth of Cancer Cells
Date:6/12/2008

Finding suggests interception of this signal may thwart metastases, study says

THURSDAY, June 12 (HealthDay News) -- Primary tumors can fuel the growth of stray cancer cells elsewhere in the body, say researchers at the Massachusetts Institute of Technology.

In experiments with mice, the MIT team found that primary tumors derived from human breast cancers seem to promote the growth of distant cancers by mobilizing bone marrow cells, which then feed the growth of the secondary tumors.

The secretion of a substance called osteopontin by the primary tumor is an important part of this process, said the researchers, who noted that osteopontin is present at elevated levels in women with metastatic breast cancer.

While the researchers found that the primary tumor somehow disturbs the make-up of bone marrow, they don't know exactly how that occurs. They also know that osteopontin does not act alone in this process.

The findings, published in the June 13 issue of Cell, may lead to new cancer treatments.

"If metastases depend on stimulation by primary tumors, interception of the signal through neutralizing antibodies," may prevent the spread of cancer, researcher Robert Weinberg said in a prepared statement. "That's still speculative, but it's an interesting idea to ponder."

He noted that current treatments don't specifically target metastases, which causes the vast majority of cancer deaths.

The findings may also prove important for the pre-clinical study of cancers.

"The ability of instigating tumors to foster the growth of a human colon tumor surgical specimen underscores the power of systemic instigation," Weinberg and colleagues wrote. "Indeed, to our knowledge, methods to expedite the growth of human tumor surgical specimens in vivo have not been previously described. These results suggest that the presently described procedure can be used to study aspects of huma
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Primary snoring in children impacts cardiovascular functioning
2. Primary care visits reduce hospital utilization among Medicare beneficiaries at the end of life
3. Aflac to be Primary Sponsor of Carl Edwards and the No. 99 Ford Fusion
4. Can pathological techniques help identify primary colorectal signet ring cell carcinoma?
5. ACP says major system reforms needed to improve the state of primary care medicine in the US
6. Patient Centered Primary Care Collaborative Releases New Guidelines for Health Care Purchasers
7. Providence Saint Joseph Medical Named LA Countys Third Primary Stroke Center
8. Cardinal Health, ClearCount Medical Solutions Sign Primary Distribution Agreement for RFID-Enabled Sponge Counting, Detection System
9. One-Third of U.S. Primary Care Physicians and Cardiologists Do Not Currently Prescribe Treatment to Meet HDL Cholesterol Targets as Recommended By National Guidelines
10. ‘15by2015’ - A Campaign to Strengthen Primary Healthcare Around the World
11. An efficient response in primary care would reduce the use of hospitals by elderly people
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... Patients who undergo radiation for a hematologic cancer ... but the disease is likely to differ in some ... Surviving Mesothelioma has just posted the details of this ... read it now. , Scientists from China, the ... who had both a hematologic cancer (like lymphoma or ...
(Date:4/18/2015)... More than 2000 styles of newly designed prom ... online store carrying celebrity inspired special occasion dresses. With ... perfect dresses for their prom. For those who are ... TheCelebrityDresses.com would be an ideal choice. , "We ... inspired by the most loved styles seen at this ...
(Date:4/18/2015)... 18, 2015 “ ArcAngel ” was featured ... a look at the latest and coolest applications ... the host of AppWatch and technology expert, conducted the app ... safety app. , In a turbulent world, people may ... 911 should always be their first move, but some situations ...
(Date:4/17/2015)... (PRWEB) April 18, 2015 Heritage Woods ... begin its Supportive Living Week Celebration on April 20 ... having a healthy mind, body and soul. , The ... McLeansboro, Illinois, serves older adults of all incomes, including ... their independence. , Supportive Living Week is observed every ...
(Date:4/17/2015)... ERGO-Pedic Products, LLC, which produces therapeutic ... products to help a broader range of people plagued ... the second most common visitors to doctors. , “The ... to help relieve sitting pain. Then, only a couple ... happy customers later, we began getting questions from those ...
Breaking Medicine News(10 mins):Health News:New Study Examines Relationship Between Radiation for Hematologic Cancers and Development of Mesothelioma, According to Surviving Mesothelioma 2Health News:Prom Dresses 2015 on Sale at TheCelebrityDresses.com 2Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Seat Cushion Company Credits Customer Driven Design For Two New Products 2
... second leading cause of hospitalization of elderly patients. In many ... complete decline in the patient,s health, setting off a long ... published in the April 2010 issue of The Journal ... person,s pre-surgical health classificationas determined by the American Society of ...
... ... Says Empire Blue Cross Puts Stockholders Ahead of Community Healthcare. As Other Health ... ... said today that its contract with Empire Blue Cross Blue Shield expired at midnight ...
... in Hong Kong and South Korea released results from ... transplantation (LDLT). A single paired exchange, performed by ... success. The Korean team reported 16 donor exchanges ... of this novel approach to organ transplantation appear in ...
... ... in real-time a key differentiator , ... Marlborough, MA (PRWEB) April 1, 2010 -- LogMatrix, a provider of log management, threat ... is currently using the LogMatrix LogCenter solution to capture and report on over 2 billion ...
... a world first study of its kind, 161 postnatal ... two separate groups to test the effect of a ... The experimental group received an eight-week "Mother and Baby" ... physiotherapist combined with parenting education. In the ...
... fibers before age 36 raises women,s odds of developing cancer, ... exposure to chemicals and pollutants before a woman is in ... after menopause, a new study has found. , The study ... they were between the ages of 50 and 75, and ...
Cached Medicine News:Health News:Hip surgery success partially predicted by number of other existing conditions 2Health News:Community Hospital Group Contract Expires With Major Health Plan Insurer 2Health News:Community Hospital Group Contract Expires With Major Health Plan Insurer 3Health News:Living donor exchange poses new option for liver transplantation 2Health News:LogMatrix Log Management Solution Easily Supports Customer's Extreme Scalability and Data Retrieval Requirements 2Health News:New mums beat the blues and increase wellbeing with physio exercise, study reveals 2Health News:Workplace Chemicals May Boost Breast Cancer Risk 2
(Date:4/17/2015)... ADELAIDE, Australia , April 17, 2015 ... the discovery and development of innovative therapeutics for the ... system, today announced the presentation of data from three ... American Association for Cancer Research (AACR) 106 th ... Philadelphia, PA USA. ...
(Date:4/16/2015)... , April 16, 2015  Hologic, Inc. ... cervical cancer screening study i published on-line ... peer-reviewed journal of the American Cancer Society. ... and the University of Pittsburgh Medical Center, supports current consensus ... recommend that women 30-65 years of age be ...
(Date:4/16/2015)... , April 16, 2015  Diplomat Pharmacy, Inc. ... Shannon Beltrand to their senior leadership team as ... be responsible for securing and properly monitoring Diplomat,s data, ... both internally and externally. Additionally, she will play key ... "We are very excited to have someone ...
Breaking Medicine Technology:Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 2Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 3Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 4Diplomat Names Shannon M. Beltrand as New CISO 2
... BioZip Suture Anchor is a unique double loaded ... is made from Poly-L Lactic Acid (PLLA) and ... are attached to the suture ends for open ... repairs. The trocar tip inserter allows insertion with ...
... LactoSorb copolymer is an absorbable ... L-Lactic acid and 18% glycolic acid. ... such as 100% poly-L-lactic acid (PLLA) ... copolymer is substantially amorphous (without crystallinity), ...
... is an absorbable co-polymer synthesized from ... 18% glycolic acid. Unlike the homopolymers ... poly-L-lactic acid (PLLA) or 100% poly-glycolic ... amorphous (without crystallinity), meaning that its ...
... The USS Sports Medicine™ POLYSORB™ Soft Tissue Anchor ... to attach soft tissue to bone using sutures. ... prepared hole in the bone, and is used ... are made of a resorbable copolymer, derived from ...
Medicine Products: