Navigation Links
Previously unknown immune cell may help those with Crohn's and colitis
Date:11/3/2008

The tonsils and lymphoid tissues in the intestinal tract that help protect the body from external pathogens are the home base of a rare immune cell newly identified by researchers at Washington University School of Medicine in St. Louis. The researchers indicate that the immune cells could have a therapeutic role in inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

Their report will appear in an upcoming issue of the journal Nature and is currently available through advanced online publication.

"These cells have an anti-inflammatory effect," says the article's lead author Marina Cella, M.D., research associate professor of pathology and immunology. "In the gut, we have beneficial bacteria, and it's important that the body does not recognize them as something detrimental and start an inflammatory reaction, which could ultimately promote tissue damage and inflammatory or autoimmune diseases such as IBD. The cells we've discovered are important for keeping such harmful inflammatory processes in check."

The cells are a type of natural killer (NK) cells, which are white blood cells classically known to eliminate tumor cells and cells infected by viruses. Because of their killer tendencies, NK cells are carefully controlled and don't act until they receive the right signal.

Some of the signals that activate the newly discovered cells are the same signals that turn on a different immune cell with strong inflammatory properties that can promote cell death and tissue damage if chronically active. But the anti-inflammatory cells, termed NK-22 cells, that the Washington University researchers discovered have the opposite effect they promote cell proliferation and wound healing.

"That finding suggests that these cells play a role in maintaining a balance in the immune system between inflammatory processes and anti-inflammatory processes," says coauthor Jason Mills, M.D., Ph.D., assistant p
'/>"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Brain cells work differently than previously thought
2. Bristol-Myers Squibb Finalizes Settlement of Previously Disclosed Federal Investigation into Pricing, Sales and Marketing Practices
3. New transfusion rules restrict donations from previously pregnant women
4. Z Trim Holdings Reports Restatement of Previously Issued Financial Statements; Amends Bylaws
5. CDC Reports Prevalence of Worms Transmitted by Dogs and Cats to Humans is Higher Than Previously Understood
6. China Sky One Medical Completes Previously Announced Amendment to 2006 Form 10KSB
7. Symmetry Medical Provides Update of Previously Disclosed Accounting Review at Sheffield, UK Operating Unit
8. More functional DNA in genome than previously thought
9. The Ensign Group, Inc. Acquires Assets of Three Previously Leased Facilities
10. HealthSouth Announces Final Agreement on Previously Disclosed Settlement with Federal Government
11. China Sky One Medical Completes Previously Announced Amendments to Form 10QSB for the Second and Third Quarters of 2006
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... kind, Rice University researchers have mapped how information flows ... become metastatic. The research reveals a common pattern in ... and form new tumors. Researchers say the commonality may ... the genetic switches that cancer must flip to form ... two of the main players in cancer metastasis. , ...
(Date:10/31/2014)... Colorado (PRWEB) October 31, 2014 Daily Gossip ... method is actually described as the fastest fat loss program ... in less than a month. , There is no wonder ... loss eBook of all time. The new nutrition and workout ... nutrition and fitness expert. , According to the author ...
(Date:10/31/2014)... 2014 With all the preparations families ... feels they may overlook one critical area – the ... concentration, school performance and even behavior. Typical children’s vision ... identify progressive vision problems, and to address this challenge, ... new initiative: The Awesome Eyes Student Vision Program. ...
(Date:10/31/2014)... may make it hard for you to remember simple things, ... house keys, a small study suggests. Tests on 18 ... called spatial memory -- was impaired when sleep apnea disrupted ... sleep weren,t affected. REM sleep is the deepest level of ... the first time that sleep apnea, an increasingly common medical ...
(Date:10/31/2014)... four older Americans say that either they or a ... according to the latest issue of The Gerontological Society ... ( PP&AR ), which goes on to show that ... to honor patients, end-of-life health care wishes. , This ... and Options ," features 12 articles that present new ...
Breaking Medicine News(10 mins):Health News:Decoding the emergence of metastatic cancer stem cells 2Health News:Decoding the emergence of metastatic cancer stem cells 3Health News:Xtreme Fat Loss Diet Review Reveals How to Transform Your Body in 25 Days 2Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 2Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 3Health News:Sleep Apnea May Steal Some of Your Memory: Study 2Health News:Advance directives can benefit patients, families, and health care system 2
... The nation,s theater owners were asked today by the head of a major Hollywood studio to have healthier snacks at their concession stands in addition to their ... ... ... ...
... eight times more likely to die, study finds , MONDAY, March ... hip are five to eight times more likely to die in ... Belgian researchers has found. , And, while the death rate after ... the break, it never returns to the death rate seen in ...
... of Medicine (BUSM) believe teaching the subject of unhealthy ... training and can be done within existing teaching venues. ... Medical Education , represent a national model for addressing ... use can be serious and chronic and despite its ...
... March 15 The HIMSS Electronic Health ... on two major regulations that implement healthcare IT incentive ... 2009 (ARRA).  One comment addressed the Office of the ... (IFR) on EHR certification criteria and standards.  The other ...
... mouse study suggests , MONDAY, March 15 (HealthDay News) ... a major role in regulating blood pressure, but a ... could also be key, at least after menopause begins. ... to have female chromosomes (XX) and females to have ...
... Mouse study suggests treatment aimed at immune system could work ... cells may one day be a viable treatment for people ... published online in the March 15-19 early edition of the ... its idea from the field of organ transplantation, where multipotent ...
Cached Medicine News:Health News:Movie Theaters Asked to Offer Healthier Snacks at Concession Stands 2Health News:Movie Theaters Asked to Offer Healthier Snacks at Concession Stands 3Health News:Movie Theaters Asked to Offer Healthier Snacks at Concession Stands 4Health News:Movie Theaters Asked to Offer Healthier Snacks at Concession Stands 5Health News:Movie Theaters Asked to Offer Healthier Snacks at Concession Stands 6Health News:Risk of Death Persists After a Hip Fracture 2Health News:Risk of Death Persists After a Hip Fracture 3Health News:Researchers recommend curriculum on unhealthy substance use 2Health News:HIMSS Electronic Health Record Association Responds to Proposed Meaningful Use and Certification Rules 2Health News:HIMSS Electronic Health Record Association Responds to Proposed Meaningful Use and Certification Rules 3Health News:HIMSS Electronic Health Record Association Responds to Proposed Meaningful Use and Certification Rules 4Health News:HIMSS Electronic Health Record Association Responds to Proposed Meaningful Use and Certification Rules 5Health News:Women's Chromosomes May Affect Blood Pressure 2Health News:Stem Cells Might One Day Treat Severe Asthma 2
(Date:10/31/2014)... -- Australian biopharmaceutical company Specialised Therapeutics Australia (STA) is pleased ... combination with gemcitabine, will be reimbursed via the Pharmaceutical ... from 1 November. In ... most common cause of cancer mortality. Pancreatic cancer ... lowest 5-year survival of all common cancers at 5.2%. ...
(Date:10/31/2014)... -- Oramed Pharmaceuticals Inc. (NASDAQCM: ORMP)( ... the development of oral drug delivery systems, announces ... to discuss the clinical results from its Phase ... oral insulin capsules, to treat type 1 diabetes ... Eastern time. Shareholders and other interested ...
(Date:10/31/2014)... -- Today, Analysts Review released its research ... Bristol-Myers Squibb Co. (NYSE: BMY ), UnitedHealth ... (NYSE: SNY ) and Actavis plc (NYSE: ... publication. To reserve complementary membership, limited openings are available ... Reports ,On October 23, 2014, Celgene Corporation (Celgene) reported ...
Breaking Medicine Technology:Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 2Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 3Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 4Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 5Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 6Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 7Specialised Therapeutics Australia Announces Breakthrough Cancer Drug Abraxane(R) to be PBS Listed for Metastatic Pancreatic Cancer 8Oramed to Report Key Top Line Results from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed to Report Key Top Line Results from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 2Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 3Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 4Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 5Financial Results, Acquisition Agreement, and Legal Issue Update - Research Reports on Celgene, Bristol-Myers, UnitedHealth, Sanofi and Actavis 6
... BOZEMAN, Mont., May 01, 2007 /PRNewswire/ -- ... with their influenza virus-like particles (VLPs),induced heterosubtypic ... data were presented by Dr. Joel Haynes, ... Tenth Annual Conference on,Vaccine Research sponsored by ...
... 3, 2007 - Insmed Inc.,(Nasdaq:INSM) today announced positive ... company's drug, IPLEX(TM), in,patients with myotonic muscular dystrophy ... conducted at,the University of Rochester School of Medicine ... doses of IPLEX up to 1,mg/kg/day in six ...
Cached Medicine Technology:LigoCyte Pharmaceuticals Presents Data Showing Heterosubtypic,Protection Against Influenza Challenge With Virus-Like Particle,Immunization 2Insmed Announces Promising Results From IPLEX Phase II Myotonic,Muscular Dystrophy Clinical Study 2Insmed Announces Promising Results From IPLEX Phase II Myotonic,Muscular Dystrophy Clinical Study 3Insmed Announces Promising Results From IPLEX Phase II Myotonic,Muscular Dystrophy Clinical Study 4
... the solid, tested XiIIIPlus platform, the ... an unprecedented level of on-demand printing ... as unique features such as XML ... automatic calibration, flexible inlay positioning, multiple ...
... Built on the solid, tested ... offers an unprecedented level of on-demand ... well as unique features such as ... systems, automatic calibration, flexible inlay positioning, ...
... is ideal for applications that ... labels, such as tracking printed ... and identifying small products. The ... ensures text, graphics and bar ...
... The 105SL is the ... S Series™, and its also ... and processing capacity with rugged ... on a proven platform, the ...
Medicine Products: