Navigation Links
Previous pulmonary disease linked to increased lung cancer risk in large study
Date:8/14/2014

Links between a number of common respiratory diseases and an increased risk of developing lung cancer have been found in a large pooled analysis of seven studies involving more than 25,000 individuals.

"Associations between various respiratory diseases and lung cancer have been shown in earlier studies, but few of these studies considered multiple respiratory diseases simultaneously," said researcher Ann Olsson, PhD, of the International Agency for Research in Cancer in Lyon, France. "In our pooled analysis of seven case-control studies involving more than 12,500 cases and 14,900 controls, we found associations between lung cancer and chronic bronchitis, emphysema, and pneumonia, with a greater increased lung cancer risk among subjects with all three of these conditions."

The findings were published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Data on five previous respiratory diseases (chronic bronchitis, emphysema, tuberculosis, pneumonia, and asthma) were collected by self-report. Statistical analyses were adjusted for study center, age, employment in an occupation with an excess risk of lung cancer, level of education and detailed smoking habits.

Pneumonia and chronic bronchitis were the most frequently reported previous respiratory diseases. In analyses adjusting for other respiratory diseases and smoking, chronic bronchitis and emphysema were positively associated with lung cancer, with odds ratios among men of 1.33 (95% CI 1.20-1.48) for bronchitis and 1.50 (95% CI 1.21-1.87) for emphysema. A positive association was also found between pneumonia diagnosed two or fewer years prior and lung cancer (OR=3.31; CI 2.33-4.70 for men), Asthma had an inverse association with lung cancer risk, and no association was found between tuberculosis and lung cancer.

Patients with co-occurring chronic bronchitis, emphysema and pneumonia had a higher risk of lung cancer than those with chronic bronchitis only. There was no association between chronic bronchitis and lung cancer among patients with co-occurring asthma or tuberculosis.

"The variations in the associations between lung cancer and different patterns of previous respiratory diseases that we observed in our study may indicate differences in the underlying etiological mechanisms," said Dr. Olsson. "Better understanding of these associations may help guide the type and frequency of clinical surveillance needed for patients with each of these diseases."


'/>"/>
Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Diagnostic yield of colonoscopy for melena after nondiagnostic upper endoscopy is lower than previously reported
2. Blacks, Hispanics Have Higher Colon Polyp Risk Than Previously Thought
3. Cancer may require simpler genetic mutations than previously thought
4. HIV superinfection in Uganda may be more common than previously thought, study finds
5. Genome-wide analysis shows previously undetected abnormalities in parents of affected children
6. Benefits of HIV drugs rise -- but less than previously believed, Penn study shows
7. HIV suppression not as good as previously thought, largest study of viral-load blood tests show
8. Survival rates for premature babies in high-level NICUs are better than previously reported
9. The aging brain is more malleable than previously believed
10. Physicians at Pain Care Bring Hope to Hundreds of Pain Management Patients Who Previously Had None Through Use of a New Procedure Called Spinal Cord Stimulation
11. Previous studies on toxic effects of BPA couldnt be reproduced
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... ... financial consultation services from offices located in South Lyon, Dewitt, Williamston, East Lansing, ... a basketball coach who needs treatment for a brain tumor. , Jason Bauer ...
(Date:12/7/2016)... NY (PRWEB) , ... December 07, 2016 , ... A. ... business owners and families throughout the Five Boroughs, is launching a charity drive to ... works to continue the traditions and spirit of marines and Navy FMF Corpsmen. Working ...
(Date:12/7/2016)... ... December 07, 2016 , ... Delete® - Tattoo Removal and Laser Salon ... Party Season. Save Up To 33% Off Botox® and Juvederm® Products Now Through December ... Valley with Delightful Deals on Botox® and Juvederm® just in time for ...
(Date:12/7/2016)... CINCINNATI, Ohio (PRWEB) , ... December 07, 2016 ... ... winner in the 2016 BOC Business Brilliance Awards under the Best New Product ... inception and results achieved through user experience. , BOC Global Events & Training ...
(Date:12/7/2016)... ... December 07, 2016 , ... “Walking With God: Inspirational Lessons from ... inspire the reader to be aware of God's direction in their lives. “Walking With ... Smith, retired teacher and active church leader. , Sanford says, “I enjoy ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... 7,2016  Based on its recent analysis ... & Sullivan recognizes Nemaura Pharma Limited with ... for Enabling Technology Leadership. Nemaura Pharma,s transdermal ... traditional drug delivery technologies, especially in delivering ... delivery technologies, Memspatch and Micropatch respectively, facilitate ...
(Date:12/7/2016)... , Dec. 7, 2016  Lannett Company, Inc. (NYSE: ... BMO Capital Markets 2016 Prescription for Success Healthcare Conference on December ... in New York City . In ... at the Guggenheim Securities 4 th Annual Boston Healthcare Conference ... ...
(Date:12/6/2016)... Dec. 6, 2016 Radioisotopes are radioactive isotopes ... produced either by using nuclear research reactor or by ... of alpha, beta or gamma when changed to a ... in Nuclear medicine, specifically in medical diagnostics. In this ... about a human body,s functioning. Radiotherapy is also used ...
Breaking Medicine Technology: