Navigation Links
Previous pulmonary disease linked to increased lung cancer risk in large study
Date:8/14/2014

Links between a number of common respiratory diseases and an increased risk of developing lung cancer have been found in a large pooled analysis of seven studies involving more than 25,000 individuals.

"Associations between various respiratory diseases and lung cancer have been shown in earlier studies, but few of these studies considered multiple respiratory diseases simultaneously," said researcher Ann Olsson, PhD, of the International Agency for Research in Cancer in Lyon, France. "In our pooled analysis of seven case-control studies involving more than 12,500 cases and 14,900 controls, we found associations between lung cancer and chronic bronchitis, emphysema, and pneumonia, with a greater increased lung cancer risk among subjects with all three of these conditions."

The findings were published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Data on five previous respiratory diseases (chronic bronchitis, emphysema, tuberculosis, pneumonia, and asthma) were collected by self-report. Statistical analyses were adjusted for study center, age, employment in an occupation with an excess risk of lung cancer, level of education and detailed smoking habits.

Pneumonia and chronic bronchitis were the most frequently reported previous respiratory diseases. In analyses adjusting for other respiratory diseases and smoking, chronic bronchitis and emphysema were positively associated with lung cancer, with odds ratios among men of 1.33 (95% CI 1.20-1.48) for bronchitis and 1.50 (95% CI 1.21-1.87) for emphysema. A positive association was also found between pneumonia diagnosed two or fewer years prior and lung cancer (OR=3.31; CI 2.33-4.70 for men), Asthma had an inverse association with lung cancer risk, and no association was found between tuberculosis and lung cancer.

Patients with co-occurring chronic bronchitis, emphysema and pneumonia had a higher risk of lung cancer than those with chronic bronchitis only. There was no association between chronic bronchitis and lung cancer among patients with co-occurring asthma or tuberculosis.

"The variations in the associations between lung cancer and different patterns of previous respiratory diseases that we observed in our study may indicate differences in the underlying etiological mechanisms," said Dr. Olsson. "Better understanding of these associations may help guide the type and frequency of clinical surveillance needed for patients with each of these diseases."


'/>"/>
Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Diagnostic yield of colonoscopy for melena after nondiagnostic upper endoscopy is lower than previously reported
2. Blacks, Hispanics Have Higher Colon Polyp Risk Than Previously Thought
3. Cancer may require simpler genetic mutations than previously thought
4. HIV superinfection in Uganda may be more common than previously thought, study finds
5. Genome-wide analysis shows previously undetected abnormalities in parents of affected children
6. Benefits of HIV drugs rise -- but less than previously believed, Penn study shows
7. HIV suppression not as good as previously thought, largest study of viral-load blood tests show
8. Survival rates for premature babies in high-level NICUs are better than previously reported
9. The aging brain is more malleable than previously believed
10. Physicians at Pain Care Bring Hope to Hundreds of Pain Management Patients Who Previously Had None Through Use of a New Procedure Called Spinal Cord Stimulation
11. Previous studies on toxic effects of BPA couldnt be reproduced
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... On ... as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle ... honor of the city’s history as home to some of the world’s leading providers ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand ... project," said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s ... within Final Cut Pro X . Simply select a ProHand generator and drag ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... Forecast to 2022" report to their offering. ... the patients with kidney failure, it replaces the function of ... patient,s blood and thus the treatment helps to keep the ... balance. Increasing number of ESRD patients & ...
Breaking Medicine Technology: