Navigation Links
Previous Cancer May Up Melanoma Risk
Date:12/19/2011

MONDAY, Dec. 19 (HealthDay News) -- A new study finds that cancer survivors are at increased risk for cutaneous melanoma, one of the most aggressive forms of skin cancer. The highest risk is among those previously diagnosed with melanoma.

Cutaneous melanoma is the fifth most commonly diagnosed cancer in U.S. men and the seventh most commonly diagnosed cancer in U.S. women. Incidence of the cancer is increasing, and death rates from the disease have decreased little, despite survival gains for other types of cancer, according to background information in the study.

Ultraviolet radiation exposure is the greatest risk factor for cutaneous melanoma, but race and genetics also influence the risk.

In this study, researchers analyzed data from about 70,800 U.S. patients who were diagnosed with cutaneous melanoma as a first primary cancer (median age of 54 at time of diagnosis) and 6,353 patients who were diagnosed with cutaneous melanoma (average age of 70 at time of diagnosis) after surviving a previous cancer.

Patients with a previous melanoma diagnosis were more likely to develop cutaneous melanoma, said Geoffrey B. Yang, a medical student at Case Western Reserve School of Medicine, in Cleveland, and colleagues.

Among patients younger than 45 at first cancer diagnosis, 777 developed cutaneous melanoma. Those at significantly higher risk included those previously diagnosed with cutaneous melanoma or other skin cancers, Kaposi sarcoma, breast cancer or lymphoma.

Among patients who were 45 or older at first cancer diagnosis, the risk of developing cutaneous melanoma was much higher among those previously diagnosed with cutaneous melanoma or other skin cancers, ocular melanoma, breast cancer, prostate cancer, lymphoma and leukemia.

"Characteristics associated with better survival in both (groups) included female sex, age younger than 45 years at melanoma diagnosis, being married, being white vs. black, decreasing Breslow depth [how deeply tumor cells have invaded], lack of tumor ulceration, no nodal involvement, and absence of metastases [the spread of cancer from the primary tumor to other locations in the body]," the researchers wrote in a journal news release.

The results suggest the need for continued skin surveillance in melanoma survivors, they concluded.

The study appears in the December issue of the journal Archives of Dermatology.

Dr. Michele Green, a dermatologist at Lenox Hill Hospital in New York City, said that people tend to think of melanoma "as 'lightening doesn't strike twice,' but unfortunately, there are both genetic and environmental reasons which make this a faulty comparison. A history of malignant melanoma makes you at an increased risk for a second primary melanoma and [you] definitely need constant monitoring.

"This risk remains elevated for over 15 years. This was a very important study which illustrated what I have seen in private practice over the past 20 years," she added.

More information

The U.S. National Cancer Institute has more about melanoma and other skin cancers.

-- Robert Preidt

SOURCE: Michele Green, M.D., dermatologist, Lenox Hill Hospital, New York City; JAMA/Archives journals, news release, Dec. 19, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Pig-induced pluripotent stem cells may be safer than previously thought
2. MS May Take a Different Pathway Than Previously Thought
3. Post-traumatic stress risk to police officers lower than previously thought
4. Incidence of non-fatal pediatric firearm injuries in the US higher than previously estimated
5. Study finds consumers may have more control over health costs than previously thought
6. Previous Infant Death Linked to Raised Risk of Stillbirth
7. Risk of autism among younger siblings of a child with autism much greater than previously reported
8. Review of 700,000 women reveals factors affecting vaginal birth after previous cesarean
9. YERVOY (ipilimumab) approved for the treatment of previously treated advanced melanoma in the EU
10. Previous cancer history increases chances of clotting disorders after knee surgery, study suggests
11. Barretts esophagus carries lower risk of malignancy than previously reported
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Previous Cancer May Up Melanoma Risk
(Date:6/27/2016)... ... , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best Buy Eyeglasses, ... the United States and Canada wear eyeglasses. Once considered to be a purely functional ... a fashion statement. Even celebrities use glasses as a way of creating an iconic ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Pixel Film Studios ... X. , "Film editors can give their videos a whole new perspective by using ... - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 Different ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women ... diagnosed with endometriosis. These women need a treatment plan to not only alleviate ... that can help for preservation of fertility and ultimately achieving a pregnancy. The ...
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
Breaking Medicine Technology: